INTRODUCTION

Methyl magnesium chloride is the simplest of Grignard’s reagents. The neat molecule is sensitive to air and moisture. Therefore, it is offered as solution in THF with variable molarity values. At low temperature, it may crystallize out as THF complex and regain solution form at ambient temperature.

Manufacture
The product is manufactured by reaction of chloromethane with magnesium in anhydrous diethyl ether. The synthesis generally requires presence of an initiator.

SynonymsMethyl (chloro) magnesium
Magnesium carbanide chloride
CAS no.676-58-4
EINECS no.211-629-7
Molecular formulaCH3MgCl
Molecular weight74.79
Structure

Applications

APIs
Ganaxolone, a synthetic neuroactive steroid
Medetomidine, a sedative veterinary
Chlorphenoxamine, an anticholinergic
Clemastine, an antihistamine
Intermediates
Dimethyl magnesium
Tetramethyl lead
Tetramethyl tin
Bis(cyclopentadienyl)dimethyl titanium
Styrallyl alcohol
2,6-Dimethyl-2-heptanol
Dimethyl phenethyl carbinol
Flavors & Fragrances
Hydroxycitronellal, an odorant with floral fragrance
Propenyl guaethol, flavor ingredient with vanilla odor
Others
Selective methylation agent for aldehydes, ketones, and carbonyls in organic syntheses

SPECIFICATIONS

TestUnitSpecification
AppearanceDark brown to grey coloured liquid
MolarityM2.90 – 3.30
Sedimentation%Max 2.0

STORAGE
Stored at ambient temperature under nitrogen blanket

PACKING
190 kg UN approved HDPE drums

REACH Status
Not registered yet

ExSyn offers methyl magnesium chloride on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

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