INTRODUCTION

Methyl magnesium chloride is the simplest of Grignard’s reagents. The neat molecule is sensitive to air and moisture. Therefore, it is offered as solution in THF with variable molarity values. At low temperature, it may crystallize out as THF complex and regain solution form at ambient temperature.

Manufacture
The product is manufactured by reaction of chloromethane with magnesium in anhydrous diethyl ether. The synthesis generally requires presence of an initiator.

SynonymsMethyl (chloro) magnesium
Magnesium carbanide chloride
CAS no.676-58-4
EINECS no.211-629-7
Molecular formulaCH3MgCl
Molecular weight74.79
Structure

Applications

APIs
Ganaxolone, a synthetic neuroactive steroid
Medetomidine, a sedative veterinary
Chlorphenoxamine, an anticholinergic
Clemastine, an antihistamine
Intermediates
Dimethyl magnesium
Tetramethyl lead
Tetramethyl tin
Bis(cyclopentadienyl)dimethyl titanium
Styrallyl alcohol
2,6-Dimethyl-2-heptanol
Dimethyl phenethyl carbinol
Flavors & Fragrances
Hydroxycitronellal, an odorant with floral fragrance
Propenyl guaethol, flavor ingredient with vanilla odor
Others
Selective methylation agent for aldehydes, ketones, and carbonyls in organic syntheses

SPECIFICATIONS

TestUnitSpecification
AppearanceDark brown to grey coloured liquid
MolarityM2.90 – 3.30
Sedimentation%Max 2.0

STORAGE
Stored at ambient temperature under nitrogen blanket

PACKING
190 kg UN approved HDPE drums

REACH Status
Not registered yet

ExSyn offers methyl magnesium chloride on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Sodium Trifluoroacetate
Products in focus · 26/03/2024

Sodium trifluoroacetate is a colorless organic solid belonging to category of fluoro compounds. It acts as a versatile trifluoromethylation agent in chemicals synthesis and is used to produce an array of chemical intermediates.

READ MORE
In Focus : Iodopropynyl butylcarbamate
Products in focus · 19/03/2024

Iodopropynyl butylcarbamate, also known as IPBC, is an antimicrobial ingredient commonly used in cosmetics. It appears as a white, crystalline powder. It is not a paraben; it belongs to a different chemical class called carbamates. It is soluble in both water and oil-based systems. IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology.

READ MORE
In Focus : Stevia Extract (RA-98%)
Products in focus · 12/03/2024

Stevia extract with Rebaudioside A (98%) is one of the sweet tasting steviol glycoside, extracted and purified from Stevia rebaudiana (Bertoni) – a small perennial shrub also known as “Honey leaf”. The leaves of S. rebaudiana contain more than 30 different steviol glycosides, among which stevioside and rebaudioside A are present in the highest levels. It is non-nutritive and tastes approximately 200-300 times sweeter than sucrose.

READ MORE
In Focus: Protoporphyrin IX Dimethyl Ester
Products in focus · 05/03/2024

Protoporphyrin IX dimethyl ester, abbreviated PPMX, is an organic moiety belonging to category porphyrins. On exposure to light, PPMX releases reactive oxygen that can be used to destroy targeted cancer cells and thus it find applications largely in medicines.

READ MORE
In Focus: Cetylpyridinium chloride monohydrate
Products in focus · 28/02/2024

Cetylpyridinium chloride is the chloride salt form of cetylpyridinium, a quaternary ammonium with broad-spectrum antimicrobial activity. Upon topical administration, cetylpyridinium chloride is positively charged and reacts with the negatively charged microbial cell surfaces, thereby destroying the integrity of the cell membrane.

READ MORE
In Focus:N2-isobutyryl-2′-OMe-guanosine
Products in focus · 20/02/2024

N2-Isobutyryl-2′-O-methyl-guanosine (IBG) is a modified nucleoside that has gained significant attention in recent years due to its potential therapeutic and industrial applications. IBG is a derivative of guanosine, a nucleoside that is a building block of RNA and DNA.

READ MORE
In Focus: Trimethylaluminium, 2M in Toluene
Products in focus · 13/02/2024

Trimethylaluminium belongs to class of organometallics. It is a highly reactive chemical and its solution in toluene is normally used to facilitate workability. Its general applications are in cross coupling and carboalumination reactions.

READ MORE
In Focus : Octenidine Dihydrochloride
Products in focus · 06/02/2024

Octenidine dihydrochloride is a cationic surfactant, with a gemini-surfactant structure. Since 1987, it has been used primarily in Europe as an antiseptic prior to medical procedures, including on neonates. It is safe to handle and chemically stable.

READ MORE
In Focus : Allyl Glycidyl Ether
Products in focus · 30/01/2024

Allyl Glycidyl Ether (AGE) is a multifunctional organic intermediate made from epichlorohydrin and allyl chloride and is featured by high functionality and low chlorine content. Since it has an epoxy group and an allyl group, AGE reacts with a wide range of compounds.

READ MORE