4-Methoxypyridine, a molecule with ether function, is a reactive base. Its nitrogen atom is activated by the methoxy group. It renders the molecule active and thus 4-methoxypyrimidine participates in many chemical processes. Its uses are in intermediates, in synthesis of biologically active moieties, and in proteomic research.
Author archives: admin
NEW DRUGS (AMENDMENT) RULES,2022 MANDATES QR CODES FOR ACTIVE PHARMACEUTICAL INGREDIENTS
The amendment makes QR codes mandatory on every active pharmaceutical ingredient. The Amendment Rules will come into force from January 01, 2023.
European Green Deal
On June 22, 2022, the Commission adopted pioneering proposals to restore damaged ecosystems and bring nature back across Europe, from agricultural land and seas, to forests and urban environments. The Commission also proposes to reduce the use and risk of chemical pesticides by 50% by 2030.
Neoadjuvant Dostarlimab is a promising treatment option in locally advanced dMMR rectal cancer
According to New York Times, in a small clinical trial, 18 patients took a drug called Dostarlimab for around six months, and in the end, every one of them saw their tumours disappear.
In focus: Ammonium acetate
Ammonium acetate is a crystalline white solid with a somewhat acetous odour. It is also called the spirit of Mindererus in its aqueous form or Azanium acetate. It is widely used in chemical analysis, in preserving foods, and in pharmaceuticals. It is often used to prepare buffer solutions as it is made up of a weak base and a weak acid combined together.
In focus: 2,6-Lutidine
2,6-Lutidine is a liquid product and a semi-volatile compound naturally abundant in tobacco. Its main applications is as reagent in pharmaceuticals and as a solvent in chemical processes.
In focus: N,N-Dimethylthiocarbamoyl Chloride
Dimethylthiocarbamoyl Chloride is an organosulfur compound, a yellow solid. It is often encountered as a yellow syrup. It is a key reagent in the synthesis of arylthiols via the Newman-Kwart rearrangement.
In focus: Tetrafluorobenzyl bromide
Tetrafluorobenzyl bromide (TFBB), by virtue of presence of 5 fluorine atoms, is a strong electrophile and hence readily combines with nucleophiles. This property results in its extensive usage in derivatization gas chromatography. Commercially, PFBB is applied to make the corresponding alcohol and chloride.
Global recession? Not yet…
As the war in Ukraine and pandemic disruptions continue to wreak havoc on supply chains, stagflation is here to stay – marked by low growth and high inflation for at least the next 12 months.
The pandemic as well as the war in Ukraine have stifled supply of commodities and goods and upended efficient distribution through global supply chains, forcing up prices of everyday goods such as fuel and food.
Roche develops unique PCR tests to detect the monkeypox virus
Roche and its subsidiary TIB Molbiol have developed three unique LightMix® Modular Virus kits in response to recent monkeypox virus concerns. Multiple clusters of the monkeypox virus have been reported within the past two weeks in several European countries and North America, which are regions where the virus is not normally found.
In focus: Withania somnifera (Ashwagandha)
Ashwagandha also known as Withania somnifera, Winter cherry, or Indian Ginseng. Ashwagandha, one of the most valuable herbs in the Ayurvedic medical system dating back more than 3,000 years. Because of its vast area of application, ayurvedic physicians have used it extensively in curing people from their ailments.
In focus: 4-(Dimethylamino)pyridine
4-(Dimethylamino)pyridine (DMAP) is an efficient and versatile acylation catalyst. Besides, it find uses in other chemical reactions as well as in production of APIs, agrochemicals, and intermediates.