INTRODUCTION
DL-Serine is a racemic mixture of both the D- and L-forms of the amino acid serine, which is a polar, nonessential amino acid. It is an α-amino acid characterized by its hydroxyl-containing side chain, which enables it to take part in numerous biochemical reactions and synthetic processes. It functions as a pivotal intermediate in the biosynthesis of amino acids, including glycine and cysteine, underscoring its essential role in cellular metabolism. Moreover, it constitutes a critical pharmaceutical intermediate for the synthesis of a broad spectrum of therapeutic agents and drug candidates.
Manufacture
It is manufactured via microbial fermentation, typically using corn-derived glucose as the primary carbon source. During fermentation, selected microbial strains convert carbohydrates into L-Serine through enzymatic pathways followed by isolation, purification, and racemization steps to yield DL-Serine. This biotechnological route offers a sustainable and vegan-compatible alternative to traditional chemical synthesis.
| Synonyms | 2-acetamido-3-hydroxypropanoic acid |
| CAS no. | 302-84-1 |
| EINECS no. | 206-130-6 |
| Molecular formula | C3H7NO3 |
| Molecular weight | 105.09 |
| Structure |  |
Applications
DL-Serine finds extensive applications across the pharmaceutical, nutraceutical, cosmetics and chemical industries.
| Pharmaceutical Intermediates | |
| Used as a starting material or intermediate in the synthesis of various amino acids, peptides. | |
| In manufacture of compounds such as glycine, cysteine, and other biologically active molecules. | |
| Serves as a building block in the preparation of chiral drugs and intermediates. | |
| Nutraceuticals & Dietary Supplements | |
| Functions as a nutritional additive in specific formulations aimed at supporting amino acid balance. | |
| In food fortification. | |
| Chemical & Biochemical Research | |
| Widely used as a research reagent and biochemical standard in laboratories. | |
| Serves as a precursor for various synthetic reactions. | |
| Cosmetic & Personal Care Applications | |
| Used in skin-care formulations as a conditioning or hydrating agent due to its amino acid properties. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | White crystals or crystalline powder |
| Identification (By HPLC) | – | Retention time should correspond to WRS under assay test |
| State of solution | % | NLT 98.0 |
| Loss on drying | % | NMT 0.3 |
| Residue on ignition (Sulfated) | % | NMT 0.10 |
| Chloride (Cl) | % | NMT 0.020 |
| Ammonium (NH4) | % | NMT 0.02 |
| Sulfate (SO4) | % | NMT 0.02 |
| Heavy metals (Pb) | ppm | NMT 10 |
| Iron (Fe) | ppm | NMT 10 |
| Arsenic (As2O3) | ppm | NMT 1 |
| Assay | % | 99.0 – 101.0 |
STORAGE & PRECAUTION
Store at ambient conditions
PACKING
25 kg drum
REACH Status
Not registered
ExSyn offers DL-Serine on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Choline salicylate is a salicylate salt formed from choline and salicylic acid. It is a non-steroidal anti-inflammatory agent (NSAID-type compound) mainly used for its analgesic, anti-inflammatory, and mild antiseptic properties. Unlike acetylated salicylates, it is less irritating to the gastric mucosa and is commonly used in topical oral preparations such as gels and mouth paints.
TensyraTM N-10 (Octoxinol 10; tert-octyl phenyl ethoxylate) is a non-ionic surfactant known for its excellent solubilizing and membrane-permeabilizing properties. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.It readily breaks down biological membranes to lyse cells, solubilize proteins, and permeabilize cell membranes for assays.
Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.
Ciclopirox Olamine (CPO) is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.
N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.
Blown Castor Oil (15-17 Poise) is a modified grade of Castor oil. The “15-17 Poise” specification refers to its viscosity range, indicating a medium-viscosity blown oil suitable for industrial applications requiring improved body, tackiness, and elasticity compared to regular castor oil.
Dimethylaminoethanol (DMAE) is a is a tertiary amine that is ethanolamine having two N-methyl substituents. It is clear & colourless to pale yellow liquid with ammoniacal odor. DMAE is stable at room temperature and is completely miscible with water as well as organic solvents such as alcohols and ethers. It decomposes at high temperatures. It is a versatile chemical intermediate primarily used as a curing agent for polyurethane foams and epoxy resins.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.
Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.