INTRODUCTION
2-Mercaptopyridine, a sulfur-containing heterocyclic compound, is a derivative of pyridine with a thiol functional group. This compound has garnered interest in various fields, including organic synthesis, medicinal chemistry, and materials science.
MANUFACTURE
It is synthesized by reacting 2-chloropyridine with thiourea in ethanol and aqueous ammonia. The mixture is heated to reflux, facilitating nucleophilic substitution to form the desired product. After cooling, the product is purified through filtration and recrystallization.
| Synonym | Pyridine-2-thiol, 2-Pyridyl mercaptan; 2- Pyridinethione |
| CAS no. | 2637-34-5 |
| EINECS no. | 220-131-9 |
| Molecular formula | C5H5NS |
| Molecular weight | 111.16 |
| Structure |  |
APPLICATIONS
| • Serves as a building block for the synthesis of various pharmaceutical intermediates and fine chemicals |
| • It is used in reactions involving nucleophilic substitutions and metal coordination |
| • In pest and insect management, it functions as a fungicide and pesticide, helping to crop protection |
| • Demonstrates potential antimicrobial and antioxidant properties, making it a candidate for further pharmacological studies |
| • Utilized in the development of specialty polymers and as a ligand in coordination chemistry |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Yellow Powder |
| Purity | % | Min 98.0 |
STORAGE
Keep in a dry, cool and well-ventilated place. Keep container tightly closed.
PACKING
HDPE drums
REACH Status
Not registered
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