INTRODUCTION
Chlorocresol, or 4-chloro-3-methylphenol, also known as p-chloro-m-cresol, is efficacious against various bacteria, yeast and fungi. It appears as a white crystalline solid. It is a potent disinfectant and antiseptic and acts as preservative in cosmetics, medicinal, and personal care products for both humans and animals.
MANUFACTURE
It is prepared by chlorination of m-cresol.
| Synonyms | p-Chlorocresol; 4-chloro-m-cresol; 3-Methyl-4-chlorophenol; PCMC |
| CAS no. | 59-50-7 |
| EINECS no. | 200-431-6 |
| Molecular formula | C7H7ClO |
| Molecular weight | 142.58 |
| Structure |  |
APPLICATIONS
| Chlorocresol is used to prevent infections. |
| It is used as an ingredient in some moisturizers and lotions. |
| Used as non-medicinal ingredient in medicated creams to treat skin irritations, such as eczema and fungi. |
| As preservative in products such as glues, gums, paints, inks, textiles and leather goods. |
| Also, used in various pharmaceutical products to increase shelf life. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description | – | White or almost White, crystalline powder |
| Solubility | – | Very soluble in Ethanol (96%), freely soluble in Ether, Slightly soluble in wáter. It dissolves in Solutions of Alkali hydroxides. |
| Identification | – | A) Blue color develops B) A White precipitate is formed |
| Melting range | °C | Between 63.0 to 66.0 |
| Non-Volatile matter | % | NMT 0.10 |
| Assay by Titrimetry | % | NLT 99.0 & NMT 101.0 |
| *Residual Solvents by GC | ||
| Toluene | ppm | NMT 890 |
| Benzene | ppm | NMT 2 |
PACKING
25 kg UN approved HDPE drum.
STORAGE
Store in closed container in a dry area.
CERTIFICATION
GMP, Kosher, Halal
REACH status
Not registered.
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