INTRODUCTION
1,3-Dibromopropane is an organobromine compound. A bifunctional alkyl halide, it has two bromine leaving groups that can participate in substitution or elimination reactions. It is widely used as a an intermediate in production of wide range of products including pharmaceuticals, insecticides, quaternary Ammonium compounds, flavouring agents ,fragrances and in polymer chemistry.
MANUFACTURE
1,3-Dibromopropane can be prepared via the free radical addition between allyl bromide and hydrogen bromide.
| Synonyms | Trimethylene dibromide Propane, 1,3-dibromo |
| CAS no. | 109-64-8 |
| EINECS no. | 203-690-3 |
| Molecular formula | C3H6Br2 |
| Molecular weight | 201.89 |
| Structure |  |
APPLICATIONS
1,3-Dibromopropane is useful in variety of chemical syntheses and industrial applications. Here are its main uses:
| Organic Synthesis : As precursor to heterocycles to form three- to five-membered rings for e.g. Aziridines , Pyrrolidines, pyrroles, Epoxides and other cyclic ethers. |
| In nucleophilic substitution reactions. |
| Polymer Chemistry : Used as a cross-linker in the synthesis of certain thermosetting resins or polymeric materials. |
| Intermediate in drug synthesis: To build complex molecules in pharmaceutical research. |
| In Prodrug and delivery systems. |
| Materials Science : Used to introduce functional groups onto surfaces or nanomaterials via covalent bonding. |
| Also used as a laboratory reagent. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance (By Visual) | – | Colourless to slight yellow liquid |
| Density at 20°C | gm /ml | 1.98 |
| Boiling Point | °C | 166.0 -167.0 |
| Moisture Content | % | NMT 0.5 |
| Purity (By GC) | % | NLT 99.0 |
STORAGE & PRECAUTION
Store in cool, dry place out of direct sunlight in tightly sealed containers.
PACKING
250 Kgs UN approved HDPE drums.
REACH Status
Not registered
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