INTRODUCTION
The bi-naphthol moiety is a colorless solid. The structure depicts two naphthol rings joined at the respective 1-positions. The presence of two hydroxy groups renders the molecule highly reactive and the product forms a backbone of a variety of value-added chemicals and ligands.
| Synonyms | 1,1’-bi-2-naphthol |
| CAS no. | 602-09-5 |
| EINECS no. | 210-014-0 |
| Molecular formula | C2OH14O2 |
| Structure | (download pdf to view) |
| Molecular weight | 286.32 |
APPLICATIONS
The bi-naphthyl structure serves as an important ligand for asymmetric synthesis in organic chemistry, especially in Diels-Alder reactions, carbonyl addition and reductions.
Some key applications are:
| 2,2’-bis(diphenylphosphino)-1,1’-binaphthyl (BINAP) |
| (S)-Binol by resolution of the mother binol |
| (R)-Binol in the same resolution process |
| Aluminium Lithium bi(binaphthol) (its (R)-enantiomer) |
| (S)-Vanol |
A very recent but path-breaking application of Binol has been in preparation of one of the Covid-19 vaccines being developed and supplied from India.
SPECIFICATIONS
| TEST | UNIT | SPECIFICATION |
|---|---|---|
| Appearance | – | White to off-white powder |
| Identification By IR | – | Conforms to reference spectrum |
| Identification By Proton NMR | – | Conforms to reference spectrum |
| Purity By HPLC | % | NLT 99.0 |
| Moisture | Wt. % | NMT 0.5 |
STORAGE
The product is stored at ambient temperature.
ExSyn offers this compound on commercial scale and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Diacetone Alcohol (DAA) is an aliphatic hydroxy ketone produced through the base-catalysed aldol addition of two acetone molecules. It contains both ketone and tertiary hydroxyl functionalities, offering excellent solvency and chemical reactivity.
As a high-boiling oxygenated solvent and valuable chemical intermediate, DAA finds broad application in paints and coatings, printing inks, adhesives, industrial cleaning, cosmetics, and textiles. It is also used as an intermediate in the production of mesityl oxide and MIBK. (4-methylpentan-2-one).
Kojic acid is a natural fungal metabolite produced through natural fermentation of carbohydrates. It works primarily as a tyrosinase inhibitor, suppressing melanin production to help reduce dark spots and even out skin tone. It also delivers antioxidant benefits, neutralizing free radicals and protecting skin cells from oxidative stress. With its naturally weak acidic profile, kojic acid is a multifunctional ingredient suited for brightening and protective skincare formulations.
(S)-Oxetan-2-yl-methanamine is a chiral oxetane-containing primary amine. The compound features a strained four-membered oxetane ring and an aminomethyl substituent, making it a valuable building block in modern medicinal chemistry. Due to its unique physicochemical properties, including increased polarity and metabolic stability compared with conventional alkyl groups, it is widely employed as an advanced pharmaceutical intermediate in drug discovery and development programs.
Guanidine carbonate is a white, crystalline, water-soluble compound with an alkaline and ionic nature. Composed of guanidinium cations and carbonate anions, it offers chemical stability, buffering capacity, and good formulation compatibility. In textile applications, it is used in formulations and fabric treatments for its thickening, softening, lubricating, anti-static, and flame-retardant properties, contributing to improved fabric finish and performance.
Tin(II) sulfide (SnS) has emerged as a safe and sustainable semiconductor owing to its non-toxicity, low cost, and natural abundance. It has attracted significant interest for solar energy conversion in thin-film photovoltaic devices because of its suitable band gap, which is approximately 1.3 eV in the orthorhombic phase and 1.5-1.7 eV in the cubic phase. In addition to photovoltaic applications, SnS is used in solid-state lubricants, near-infrared detectors, Lithium-ion batteries, and various sensing devices.
Nikethamide is a synthetic organic compound derived from nicotinic acid (vitamin B₃). It consists of a pyridine ring linked to a diethyl amide functional group and belongs to the class of pyridine amide derivatives.
(2-Methoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide is a stabilized phosphonium salt widely used as an intermediate in organic synthesis. Due to presence of an ester group, the compound generates a stabilized ylide that is particularly useful for synthesizing α, β-unsaturated esters, valuable intermediates in pharmaceuticals, agrochemicals, fragrances, and fine chemicals.
p-tert-Butylphenol (PTBP), is an aromatic organic compound consists of a phenol ring substituted with a tert-butyl group at the para (4-) position, giving it improved thermal stability and hydrophobic properties compared to phenol. PTBP features significant hydrogen bonding capabilities, which enhance its solubility in organic solvents. PTBP is used primarily as an intermediate in the manufacturing of polycarbonate plastics, phenolic resins, and epoxy resins.
Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.