INTRODUCTION
Tetrafluorobenzyl bromide (TFBB), by virtue of presence of 5 fluorine atoms, is a strong electrophile and hence readily combines with nucleophiles. This property results in its extensive usage in derivatization gas chromatography. Commercially, PFBB is applied to make the corresponding alcohol and chloride.
Manufacture
The product is manufactured by allylic bromination of pentafluorotoluene.
| Synonyms | (Bromomethyl)pentafluorobenzene alpha-Bromo-pentafluorotoluene |
| CAS no. | 1765-40-8 |
| EINECS no. | 217-182-4 |
| Molecular formula | C7H2BrF5 |
| Molecular weight | 260.99 |
| Structure |  |
Applications in Synthesis and Analytics
The heavily substituted aromatic is a building block for fluorinated chemicals.
In analytical laboratories, it finds extensive applications as a preferred derivatization agent in capillary gas chromatography and EC-GC.
Applications in Intermediates
| PFBB is a KRM for the synthesis of the following intermediates: |
|---|
| Pentafluorobenzyl chloride |
| Pentafluorobenzyl alcohol |
| Pentafluorobenzyl esters of organic acids |
| 2,3,4,5,6-Pentafluorophenylacetonitrile |
| (Pentafluorophenyl)acetic acid |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Clear colorless to yellow liquid |
| Purity | % | Min 98.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
25 kg drum.
REACH Status
Not registered yet.
ExSyn offers pentafluorobenzyl bromide on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
L-Phenylalanine (L-Phe) is an essential and proteinogenic amino acid that helps build proteins and produces brain chemicals like dopamine and norepinephrine. L-Phenylalanine is one of the 20 standard amino acids that form long chains called polypeptides (proteins).The body cannot produce it, so it must be obtained through diet or supplements.
L-carnitine Hydrochloride is a water soluble, stable salt form of L- Carnitine. It is a naturally occurring amino acid derivative. It is often used as a dietary supplement due to its role in energy production and fat metabolism.
Dimenhydrinate is an antihistamine drug commonly used to prevent and treat motion sickness, nausea, and vertigo. It is a combination of diphenhydramine and 8-chlorotheophylline, where the latter reduces the sedative effects of diphenhydramine. It is available in tablet, liquid, and injectable forms under various brand names.
o-Nitrophenyl Disulfide is a chemical compound used in organic chemistry and biochemistry. It is a disulfide derivative where two o-nitrophenyl groups are connected by a disulfide bond (-S-S-) It is used in various organic synthesis reactions, as a reagent in the preparation of thiol-reactive compounds, in pharmaceutical research and laboratory applications.
Tetrasodium pyrophosphate (TSPP) anhydrous is a white, crystalline or granular inorganic compound, soluble in water but insoluble in alcohol. TSPP is widely used in food, industrial, and cleaning applications due to its sequestrant, dispersing, buffering, and emulsifying properties.
Potassium sodium tartrate commonly known as Rochelle salt, is a double salt of tartaric acid. It is a white crystalline solid that is highly soluble in water. This compound is well known for its piezoelectric properties and has been historically used in various scientific and industrial applications.
Tert-Amyl Alcohol (TAA) also known as 2-Methyl-2-butanol, is a branched-chain alcohol. It is a colorless, flammable liquid with a mild alcoholic odor and moderate water solubility. Due to its unique structural properties, it is widely used as basic organic chemical in synthetic fragrances, pharmaceuticals and pigment industries.
Lithium orotate is a compound consisting of lithium, an alkali metal, and orotic acid, a natural substance involved in nucleic acid metabolism. It is a popular dietary supplement due to its potential neuroprotective and mood-stabilizing effects.
Quinuclidinone Hydrochloride is a derivative of bicyclic amine quinuclidine. The hydrochloride form of quinuclidinone is the salt form, often used for its stability in different reactions. Quinuclidinone Hydrochloride is typically used as an intermediate in the synthesis of various pharmaceuticals and other chemical products.