INTRODUCTION

Tetrafluorobenzyl bromide (TFBB), by virtue of presence of 5 fluorine atoms, is a strong electrophile and hence readily combines with nucleophiles. This property results in its extensive usage in derivatization gas chromatography.  Commercially, PFBB is applied to make the corresponding alcohol and chloride.

Manufacture
The product is manufactured by allylic bromination of pentafluorotoluene.

Synonyms(Bromomethyl)pentafluorobenzene
alpha-Bromo-pentafluorotoluene
CAS no.1765-40-8
EINECS no.217-182-4
Molecular formulaC7H2BrF5
Molecular weight260.99
Structure

Applications in Synthesis and Analytics

The heavily substituted aromatic is a building block for fluorinated chemicals.
In analytical laboratories, it finds extensive applications as a preferred derivatization agent in capillary gas chromatography and EC-GC.

Applications in Intermediates

PFBB is a KRM for the synthesis of the following intermediates:
Pentafluorobenzyl chloride
Pentafluorobenzyl alcohol
Pentafluorobenzyl esters of organic acids
2,3,4,5,6-Pentafluorophenylacetonitrile
(Pentafluorophenyl)acetic acid

SPECIFICATIONS

TestUnitSpecification
AppearanceClear colorless to yellow liquid
Purity%Min 98.0

STORAGE
The product is stored at ambient temperature.

PACKING
25 kg drum.

REACH Status
Not registered yet.

ExSyn offers pentafluorobenzyl bromide on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Sodium Trifluoroacetate
Products in focus · 26/03/2024

Sodium trifluoroacetate is a colorless organic solid belonging to category of fluoro compounds. It acts as a versatile trifluoromethylation agent in chemicals synthesis and is used to produce an array of chemical intermediates.

READ MORE
In Focus : Iodopropynyl butylcarbamate
Products in focus · 19/03/2024

Iodopropynyl butylcarbamate, also known as IPBC, is an antimicrobial ingredient commonly used in cosmetics. It appears as a white, crystalline powder. It is not a paraben; it belongs to a different chemical class called carbamates. It is soluble in both water and oil-based systems. IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology.

READ MORE
In Focus : Stevia Extract (RA-98%)
Products in focus · 12/03/2024

Stevia extract with Rebaudioside A (98%) is one of the sweet tasting steviol glycoside, extracted and purified from Stevia rebaudiana (Bertoni) – a small perennial shrub also known as “Honey leaf”. The leaves of S. rebaudiana contain more than 30 different steviol glycosides, among which stevioside and rebaudioside A are present in the highest levels. It is non-nutritive and tastes approximately 200-300 times sweeter than sucrose.

READ MORE
In Focus: Protoporphyrin IX Dimethyl Ester
Products in focus · 05/03/2024

Protoporphyrin IX dimethyl ester, abbreviated PPMX, is an organic moiety belonging to category porphyrins. On exposure to light, PPMX releases reactive oxygen that can be used to destroy targeted cancer cells and thus it find applications largely in medicines.

READ MORE
In Focus: Cetylpyridinium chloride monohydrate
Products in focus · 28/02/2024

Cetylpyridinium chloride is the chloride salt form of cetylpyridinium, a quaternary ammonium with broad-spectrum antimicrobial activity. Upon topical administration, cetylpyridinium chloride is positively charged and reacts with the negatively charged microbial cell surfaces, thereby destroying the integrity of the cell membrane.

READ MORE
In Focus:N2-isobutyryl-2′-OMe-guanosine
Products in focus · 20/02/2024

N2-Isobutyryl-2′-O-methyl-guanosine (IBG) is a modified nucleoside that has gained significant attention in recent years due to its potential therapeutic and industrial applications. IBG is a derivative of guanosine, a nucleoside that is a building block of RNA and DNA.

READ MORE
In Focus: Trimethylaluminium, 2M in Toluene
Products in focus · 13/02/2024

Trimethylaluminium belongs to class of organometallics. It is a highly reactive chemical and its solution in toluene is normally used to facilitate workability. Its general applications are in cross coupling and carboalumination reactions.

READ MORE
In Focus : Octenidine Dihydrochloride
Products in focus · 06/02/2024

Octenidine dihydrochloride is a cationic surfactant, with a gemini-surfactant structure. Since 1987, it has been used primarily in Europe as an antiseptic prior to medical procedures, including on neonates. It is safe to handle and chemically stable.

READ MORE
In Focus : Allyl Glycidyl Ether
Products in focus · 30/01/2024

Allyl Glycidyl Ether (AGE) is a multifunctional organic intermediate made from epichlorohydrin and allyl chloride and is featured by high functionality and low chlorine content. Since it has an epoxy group and an allyl group, AGE reacts with a wide range of compounds.

READ MORE