INTRODUCTION
Tetrafluorobenzyl bromide (TFBB), by virtue of presence of 5 fluorine atoms, is a strong electrophile and hence readily combines with nucleophiles. This property results in its extensive usage in derivatization gas chromatography. Commercially, PFBB is applied to make the corresponding alcohol and chloride.
Manufacture
The product is manufactured by allylic bromination of pentafluorotoluene.
| Synonyms | (Bromomethyl)pentafluorobenzene alpha-Bromo-pentafluorotoluene |
| CAS no. | 1765-40-8 |
| EINECS no. | 217-182-4 |
| Molecular formula | C7H2BrF5 |
| Molecular weight | 260.99 |
| Structure |  |
Applications in Synthesis and Analytics
The heavily substituted aromatic is a building block for fluorinated chemicals.
In analytical laboratories, it finds extensive applications as a preferred derivatization agent in capillary gas chromatography and EC-GC.
Applications in Intermediates
| PFBB is a KRM for the synthesis of the following intermediates: |
|---|
| Pentafluorobenzyl chloride |
| Pentafluorobenzyl alcohol |
| Pentafluorobenzyl esters of organic acids |
| 2,3,4,5,6-Pentafluorophenylacetonitrile |
| (Pentafluorophenyl)acetic acid |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Clear colorless to yellow liquid |
| Purity | % | Min 98.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
25 kg drum.
REACH Status
Not registered yet.
ExSyn offers pentafluorobenzyl bromide on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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