Dimethylthiocarbamoyl Chloride is an organosulfur compound, a yellow solid. It is often encountered as a yellow syrup. It is a key reagent in the synthesis of arylthiols via the Newman-Kwart rearrangement.

Dimethylthiocarbamoyl Chloride is prepared by chlorination of the related tetramethylthiuram disulfide: [Me2NC(S)]2S2 + 3 Cl2 → 2 Me2NC(S)Cl + 2 SCl. ) to give thiuram sulfides [R2NC(S)]2S. With methanethiolate, it gives methyl dimethyldithiocarbamate (Me2NC(S)SMe).

SynonymsDimethylthiocarbamoyl Chloride
N,N-Dimethylcarbamothioic Chloride
CAS no.16420-13-6
EINECS no.240-468-5
Molecular formulaC₃H₆ClNS
Molecular weight123.60


Dimethylthiocarbamoyl chloride is used as an intermediate in the synthesis of pharmaceuticals.
It finds application in chemoselective deoxygenation of pyridine-N-oxides.
It is also used as a starting reagent in the synthesis of dimethylthiocarbamates.


AppearanceYellow coloured solid
Purity%Min 98.0
Melting Point°C40.5 – 43.5
– Di Methyl Carbamoyl Chloride (DMCC)
– Other impurities


Max 1.50
Max 0.50

Store in cool place. Moisture sensitive.

20 kg UN approved HDPE drum.

REACH status
Not registered yet.

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