INTRODUCTION

4-Amino-1,2,4-triazole is an organic solid belonging to the heterocyclic category of compounds. By virtue of presence of 3 nitrogen atoms, the molecule is biologically active and thus acts as antimicrobial and antifungal agent.

Manufacture

It is manufactured by Schmidt reaction in which hydrazine reacts with an aromatic nitrile in aqueous solution to form 4-amino-1,2,4-triazole.

Synonym4H-1,2,4-triazol-4-amine
4-Amino-4H-1,2,4-triazole
CAS no.584-13-4
EINECS no.209-533-5
Molecular formulaC2H4N4
Molecular weight84.08
Structure

Applications

APIs
Carvedilol, an antihypertensive drug
Ondansetron, serotonin 5-HT3 receptor antagonist
Intermediates
1-(4-Nitrophenyl)methyl-1,2,4-triazole
4-Amino-1,2,4-triazole HCl
6,8-Dimethyl[1,2,4]triazolo[4,3-b]pyridazine
Agrochemicals
Flucanozole, a fungicide
Others
Preparation of potent, selective, and orally active cyclooxygenase-2 inhibitor
Determination of tryptophan in proteins
In FTIR spectroscopy to distinguish between various N atoms based on their vibrational frequencies

SPECIFICATIONS

TestUnitSpecifications
AppearanceWhite to off-white crystalline, hygroscopic powder
SolubilitySoluble in methanol and water
Melting range°C79  – 87
Moisture%Max 0.50
Assay (on anhydrous basis)% w/wMin 99.00

STORAGE

Stored at ambient temperature

PACKING

40 kg HDPE drum

REACH Status

Not registered

ExSyn offers 4-amino-1,2,4-triazole on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

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