INTRODUCTION
3,5-Dibromo-4-hydroxybenzoic acid is an alkylated aromatic compound with active bromo groups. They enable its multiple usages such as organic synthesis reagent, biological stain, and enzyme inhibitor. The compound is also a key intermediate in production of APIs.
Manufacture
It is manufactured by bromination of 4-hydroxybenzoic acid.
Synonym | Bromoxynylbenzoic acid 3,5-Dibromo-4-hydroxybenzoate |
CAS no. | 3337-62-0 |
EINECS no. | 222-075-0 |
Molecular formula | C7H4Br2O3 |
Molecular weight | 295.91 |
Structure |
Applications
3,5-Dibromo-4-hydroxybenzoic acid is used in synthesis of the following APIs |
---|
Epaminurad, a URAT1 inhibitor |
Benzbromarone, an uricosuric agent |
Intermediates |
---|
3,5-Dibromo-4-((trimethylsilyl)oxy)benzoyl chloride |
3,5-Dibromo-4-hydroxybenzoic acid methyl ester |
Others |
---|
As biological stain |
As fluorescent probe to detect metal ions and proteins |
In drug delivery system |
In inhibition of Cytochrome P450 |
SPECIFICATIONS
Test | Unit | Specification |
---|---|---|
Appearance | – | White to off white crystalline powder |
Identification by proton-NMR | – | Should conform to the structure |
Solubility | – | Soluble in chloroform / DMSO |
Melting point | °C | 271.0 – 274.0 |
Moisture | % | Max 1.0 |
Purity by HPLC | % | Min 98.0 |
STORAGE
Stored at ambient temperature.
PACKING
25 Kg HDPE drum with inner PP bags.
REACH Status
Not registered yet.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Boron trifluoride tetrahydrofuran complex, is a colorless liquid that is commonly used as a colorless liquid that is commonly used as a Lewis acid catalyst in various organic reactions. It has a wide range of applications in the synthesis of pharmaceuticals, polymers, and other organic compounds
Nicotinamide riboside chloride (NRCL) is a unique form of vitamin B3. As a precursor to nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme involved in various cellular processes, it has sparked interest in the realms of aging, metabolism, and overall cellular health.
Tetrachlorvinphos (popularly known as TCVP) is an agrochemical belonging to class of organophosphates. It is a non-systemic insecticide and acaracide having widespread uses in crop protection, public health, and animal hygiene.
Sodium Starch Glycolate (SSG) is a very fine free flowing powder that is white or off white in color and has almost no odor. Its property of insolubility is remarkable, with complete insolubility in most organic solvents, and even in water. It is a sodium salt of carboxyl ether of starch and is appreciated for its stability and binding properties.
3-([Ethyl(3-methylphenyl)amino]methyl) benzenesulfonic acid is an organic sulfonic acid, a white crystalline solid, which is widely used as a catalyst, acidifying agent, and a reagent in organic synthesis.
Sodium trifluoroacetate is a colorless organic solid belonging to category of fluoro compounds. It acts as a versatile trifluoromethylation agent in chemicals synthesis and is used to produce an array of chemical intermediates.
Iodopropynyl butylcarbamate, also known as IPBC, is an antimicrobial ingredient commonly used in cosmetics. It appears as a white, crystalline powder. It is not a paraben; it belongs to a different chemical class called carbamates. It is soluble in both water and oil-based systems. IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology.
Stevia extract with Rebaudioside A (98%) is one of the sweet tasting steviol glycoside, extracted and purified from Stevia rebaudiana (Bertoni) – a small perennial shrub also known as “Honey leaf”. The leaves of S. rebaudiana contain more than 30 different steviol glycosides, among which stevioside and rebaudioside A are present in the highest levels. It is non-nutritive and tastes approximately 200-300 times sweeter than sucrose.
Protoporphyrin IX dimethyl ester, abbreviated PPMX, is an organic moiety belonging to category porphyrins. On exposure to light, PPMX releases reactive oxygen that can be used to destroy targeted cancer cells and thus it find applications largely in medicines.