INTRODUCTION
2-Amino-3-methylpyridine is a heterocyclic building block used in organic chemistry to manufacture API’s, intermediates, agro-chemicals, dyes, and fragrances. The chemical reactivity of the molecule is due to presence of two substituents – amino and methyl.
Manufacture
It is manufactured by ring methylation of gamma-picoline using methyl isocyanate, the byproduct being 2-amino-5-methylpyridine The 3-methyl isomer is separated by crystallization.
Synonym | 3-Methyl-2-pyridinamine 2-Amino-gamma-picoline |
CAS no. | 1603-40-3 |
EINECS no. | 216-501-4 |
Molecular formula | C6H8N2 |
Molecular weight | 108.14 |
Structure | ![]() |
Applications
API’s |
---|
Pemirolast (anti-allergic) |
Lumacaftor (treatment of cystic fibrosis) |
Agrochemicals |
---|
Imidacloprid (insecticide) |
Intermediates |
---|
Ethyl 2-aminopyridine-3-carboxylate |
2-Amino-5-bromo-3-methylpyridine |
2-(2,2,2-Trifluoromethoxy)pyridine-3-carboxylic acid |
2-Amino-5-nitropyridine-3-carboxylic acid |
Others |
---|
Used in proteomic research |
In synthesis of nitric oxide synthase inhibitor |
SPECIFICATIONS
Test | Unit | Specification |
---|---|---|
Appearance | – | Clear colorless to pale yellow liquid / semi-solid |
Identification by GC | – | Retention time of the principal peak of sample should match with that of working standard |
Moisture | % w/v | Max 0.50 |
Purity by GC | % | Min 98.00 |
STORAGE
Stored at ambient temperature
PACKING
25 kg UN-approved HDPE drum
REACH Status
Not registered yet
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Magnesium ascorbate is a buffered (non-acidic) form of Vitamin C and a source of the essential mineral Magnesium. This does not contribute to gastric irritation in acid-sensitive persons.
Racemic quinuclidinol is an off-white solid that possesses medicinal properties. It is an alkaloid abundant in nature, especially in Erythroxylum coca. Synthetically manufactured product finds usage in APIs, intermediates, and medicinal chemistry.
Dimethylamine hydrochloride an organic chemical compound from the group of amines, is the simplest secondary aliphatic amine. It is a raw material for organic synthesis and a precursor to several industrially significant compounds.
N-Iodosuccinimide (NIS) is a heterocyclic organic compound. It is iodination and mild oxidation agent. In iodination reactions, NIS is preferred over molecular iodine for the ease of handling.
Thionyl chloride an inorganic compound, is a moderately volatile, colourless to pale yellow liquid with a pungent odour. It is also listed under the Chemical Weapons Convention as it may be used for the production of chemical weapons.
Ferrous Ascorbate is a combination of vitamin C and iron. Ferrum or iron helps to replenish the iron stores in the human body. Ascorbate contains vitamin C that improves iron levels in the body by increasing its absorption from different sources.
Diphenylphosphoryl azide, known as DPPA, is a versatile azidation agent in organic chemistry. Its applications include preparation of organo azides, production of intermediates, synthesis of lactams, and many others.
Ferrozine, chemically 3-(2-Pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine disodium salt, is a water-soluble solid. It is complexometric reagent for detection and estimation of iron.
Sodium thiosulfate is an inorganic compound, typically available as the white or colorless pentahydrate. The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water.