INTRODUCTION
Thionyl chloride an inorganic compound, is a moderately volatile, colourless to pale yellow liquid with a pungent odour. It is toxic, reacts with water, and is also listed under the Chemical Weapons Convention as it may be used for the production of chemical weapons.
Manufacture
The major industrial synthesis involves the reaction of sulfur trioxide and sulfur dichloride.
| Synonyms | Thionyl dichloride Sulfinyl chloride Sulfur chloride oxide Sulfur oxychloride Sulfurous dichloride Sulfurous oxychloride |
| CAS no. | 7719-09-7 |
| EINECS no. | 231-748-8 |
| Molecular formula | SOCl2 |
| Molecular weight | 119 |
| Structure | ![]() |
APPLICATIONS
| Here are some important uses of Thionyl chloride. |
|---|
| It is primarily utilised for the manufacturing of iso-carbophos, propargite tetramisole hydrochloride, indomethacin, and vitamin A in the pharmaceutical, pesticide, and dye industries. |
| Chlorination of alcoholic hydroxyl groups, carboxylic acid chlorination, acid anhydride chlorination, and chlorine displacement of organic sulfonic acid or carboxylic acid are all examples of chlorinating agents for organic synthesis. |
| It’s also used to make acyl chloride and pharmaceutical intermediates like tetramisole hydrochloride and synthomycin palmitate. |
| It can also be used as a solvent or a dehydrating agent. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Colourless to pale yellow liquid |
| Odor | – | Suffocating odor |
| Purity | % | Min 99.6 |
| Sulphur Chloride (as SCl2 +S2Cl2) | % | Max 0.1 |
| Sulphuryl Chloride (as SO2Cl2+ SO3) | % | Max 0.1 |
| Sulphur Dioxide (as SO2) | % | Max 0.3 |
| Iron | ppm | Max 0.2 |
| Residue on ignition | % | Max 0.01 |
| Distillation range | °C | 95% distills between 74.0 – 78.0 |
| Specific Gravity (at 20°C) | – | 1.62 – 1.64 |
PACKING
300 kg UN approved drum.
STORAGE
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
REACH Status
Thionyl chloride offered by ExSyn is registered under EU REACH regulations.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring glycosaminoglycan known for its exceptional ability to retain moisture, along with its viscoelastic and biocompatible properties, making it highly valuable across pharmaceutical, cosmetic, and biomedical applications.
Pyrazinamide is a first-line antitubercular drug used in combination therapy for the treatment of tuberculosis (TB). It is a synthetic pyrazine derivative and acts as a prodrug, which is converted into its active form (pyrazinoic acid) inside Mycobacterium tuberculosis.
6-Bromopyridine-2,3-diamine is a heterocyclic organic compound belonging to the class of substituted pyridines. It is used mainly as an intermediate in pharmaceuticals and agrochemicals.
Magnesium trisilicate is an inorganic compound commonly used in pharmaceutical and gastrointestinal (GI) preparations due to its dual action. It is usually produced as a white, odorless, fine powder. It helps bind toxins or irritants in the gastrointestinal tract and occasionally used in formulations for its stabilizing properties.
Choline salicylate is a salicylate salt formed from choline and salicylic acid. It is a non-steroidal anti-inflammatory agent (NSAID-type compound) mainly used for its analgesic, anti-inflammatory, and mild antiseptic properties. Unlike acetylated salicylates, it is less irritating to the gastric mucosa and is commonly used in topical oral preparations such as gels and mouth paints.
TensyraTM N-10 (Octoxinol 10; tert-octyl phenyl ethoxylate) is a non-ionic surfactant known for its excellent solubilizing and membrane-permeabilizing properties. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.It readily breaks down biological membranes to lyse cells, solubilize proteins, and permeabilize cell membranes for assays.
Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.
Ciclopirox Olamine (CPO) is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.
N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.
