1,4-Dibromobutane is a chemical compound from the group of aliphatic, saturated halogenated hydrocarbons. 1,4-Dibromobutane shows similar reactions as the mono-brominated 1-bromobutane, however, in contrast, it is doubly functionalized.

One way of preparing 1,4-Dibromobutane is the double bromination of 1,4-Butanediol.

SynonymsTetramethylene dibromide
1,4-Butylene bromide
CAS no.110-52-1
EINECS no.203-775-5
Molecular formulaC4H8Br2
Molecular weight215.91


1,4-Dibromobutane is used as an intermediate involved in the synthesis of active pharmaceutical ingredient for e.g. Bifemelane an antidepressant and other organic compounds.
Also used in the production of following intermediates:
* 1-(4-Methoxybutyl)hydrazine
* 1,4-Bis(diphenylphosphino)butane
* 4-Phenoxybutanoic acid
* 1,4-Dimethoxybutane
It is used in the investigation of metabolism of two halopropanes such as 1,3-Dichloropropane and 2,2-Dichloropropane.
It acts as a reagent to prepare Diazadioxa oxovanadium(IV) macrocyclic complexes.
It can be used for the alkylation of, for example, organolithium compounds or for the preparation of Grignard compounds.


AppearanceClear colorless to pale yellow liquid
Density (at 25 °C)gm/ml1.82 – 1.83
Water content (by KF)%NMT 0.1
Purity (by GC)%NLT 99.0

Tightly closed. Keep in a well-ventilated place.

250 kg HDPE drum. Also customized packing can be provided as per demand.

REACH Status
Not registered yet.

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