INTRODUCTION
o-Nitrophenyl Disulfide is a chemical compound used in organic chemistry and biochemistry. It is a disulfide derivative where two o-nitrophenyl groups are connected by a disulfide bond (-S-S-). It is used in various organic synthesis reactions, as a reagent in the preparation of thiol-reactive compounds, in pharmaceutical research and laboratory applications.
Manufacture
Synthesis process typically involves dissolution of o-nitrophenyl mercaptan in an organic solvent such as dichloromethane and subsequently oxidising it using hydrogen peroxide (H2O2) or iodine. Final compound is further purified through recrystallisation.
| Synonyms | Bis(2-nitrophenyl) disulfide; 2-Nitrophenyl Disulfide; 1,2-bis(2-nitrophenyl) disulfane |
| CAS no. | 1155-00-6 |
| EINECS no. | 214-581-5 |
| Molecular formula | C12H8N2O4S2 |
| Molecular weight | 308.33 |
| Structure |  |
Applications
Its applications span across various fields of organic synthesis, biochemistry, and analytical chemistry.
| In Biochemical research to study protein modification and cross-linking of enzyme-substrate interactions or creating enzyme complexes. |
| In disulfide bond formation in proteins. |
| As a Thiol-reacting reagent help researchers analyze protein structure and interactions. |
| In organic synthesis for sulfuration and electrophilic substitution reactions. |
| Used in creation of polymer cross-links. |
| Used in the modification of synthetic rubbers or plastics. |
| In Pharmaceutical and drug discovery research it is used as a precursor in the synthesis of other disulfide-containing molecules. |
| For synthesizing functionalized aromatic compounds. |
| In analytical chemistry used as a probe to study thiol-containing molecules and in UV-Vis spectroscopic studies. |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Yellow solid |
| Purity | % | Min. 98.00 |
STORAGE
Tightly closed and away from sources of ignition and heat.
PACKING
25 Kg HDPE Drums
REACH Status
Not registered
ExSyn offers o-Nitrophenyl Disulfide on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Nikethamide is a synthetic organic compound derived from nicotinic acid (vitamin B₃). It consists of a pyridine ring linked to a diethyl amide functional group and belongs to the class of pyridine amide derivatives.
(2-Methoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide is a stabilized phosphonium salt widely used as an intermediate in organic synthesis. Due to presence of an ester group, the compound generates a stabilized ylide that is particularly useful for synthesizing α, β-unsaturated esters, valuable intermediates in pharmaceuticals, agrochemicals, fragrances, and fine chemicals.
p-tert-Butylphenol (PTBP), is an aromatic organic compound consists of a phenol ring substituted with a tert-butyl group at the para (4-) position, giving it improved thermal stability and hydrophobic properties compared to phenol. PTBP features significant hydrogen bonding capabilities, which enhance its solubility in organic solvents. PTBP is used primarily as an intermediate in the manufacturing of polycarbonate plastics, phenolic resins, and epoxy resins.
Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.
Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate is a fluorinated aliphatic hydroxy ester. The presence of the trifluoromethyl group imparts enhanced metabolic stability, lipophilicity, and unique physicochemical properties compared with non-fluorinated analogues. This compound is primarily used as a synthetic intermediate in pharmaceutical and agrochemical research.
2-Chloro-1,1,1-trimethoxyethane is an organochlorine orthoester compound commonly used as a versatile synthetic intermediate in organic and pharmaceutical chemistry. It is a colorless to pale yellow liquid with good reactivity toward nucleophilic substitution and cyclization reactions, making it valuable in the preparation of heterocyclic and bioactive molecules.
Glycolaldehyde dimer is the cyclic dimeric form of glycolaldehyde, the simplest hydroxyaldehyde. Glycolaldehyde is often supplied as stable dimeric solid, commonly identified as 2,5-dihydroxy-1,4-dioxane.
N,N-Diisopropylethylamine (DIPEA), also known as Hünig’s Base, is a sterically hindered tertiary amine. It is a colorless liquid with a strong amine odor and is widely used as a low nucleophilic organic base in pharmaceutical, agrochemical, and fine chemical synthesis. Due to its bulky structure, DIPEA effectively scavenges acids without participating in unwanted side reactions.
Tris(2,4-di-tert-butylphenyl) phosphite (TDPP) often recognized commercially as Irgafos 168 is a high-performance organophosphorus compound primarily utilized as secondary antioxidant and processing stabilizer. Its characteristic to undergo metallation reaction and provide a cost-effective synthetic processes allows it to be useful in biaryl coupling reactions.