INTRODUCTION
Nicotinamide riboside chloride (NRCL) is a unique form of vitamin B3. As a precursor to nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme involved in various cellular processes, it has sparked interest in the realms of aging, metabolism, and overall cellular health.
MANUFACTURE
It is synthesized by reacting nicotinamide and ribose in a controlled environment to obtain nicotinamide riboside which is subsequently converted to its chloride form by reacting it with hydrochloric acid.
| Synonym | 3-(aminocarbonyl)-1-β-D-ribofuranosyl-pyridinium, monochloride |
| CAS no. | 23111-00-4 |
| EINECS no. | 807-820-5 |
| Molecular formula | C11H15ClN2O5 |
| Molecular weight | 290.7 |
| Structure |  |
| APPLICATIONS |
|---|
| It is a form of vitamin B3 (Niacin) and is marketed as a dietary supplement |
| It is being explored for its potential therapeutic applications in pharmaceuticals, including the treatment of metabolic disorders and neuro degenerative diseases |
| It may also find applications in the cosmetics industry for its potential anti-aging properties and skin health benefits |
| It is used as a research tool in scientific studies investigating its effects on metabolism, aging, and various health conditions |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | White to off-white powder |
| Identification by HPLC | – | The retention time should match with the standard |
| Purity | % | ≥ 99.0 |
| Nicotinamide | % | ≤ 1.0 |
| Single unidentified impurity | % | ≤ 0.5 |
| Heavy Metals | ppm | ≤ 20 |
| Residue on ignition | % | ≤ 0.5 |
| Ethanol | ppm | ≤ 5000 |
| Methanol | ppm | ≤ 1000 |
| ACN | ppm | ≤ 100 |
| Water content | % | ≤ 1.0 |
| Loss on drying | % | ≤ 0.5 |
| Assay | % | 98.0-102.0 |
| Aerobic bacterial count | CFU/g | ≤ 750 |
| E. Coli | MPN/g | ≤ 30 |
STORAGE
Store in dry, dark place at temperature between 2 – 8°C, avoid direct sunlight
PACKING
HDPE drums
REACH Status
Not registered
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