INTRODUCTION

Boron trifluoride tetrahydrofuran complex, is a colorless liquid that is commonly used as a colorless liquid that is commonly used as a Lewis acid catalyst in various organic reactions. It has a wide range of applications in the synthesis of pharmaceuticals, polymers, and other organic compounds. The BF3·THF complex is known for its ability to activate nucleophiles and facilitate reactions such as Friedel-Crafts acylation and alkylation. It is also used as a reagent in the preparation of boron-containing compounds. Overall, it plays a crucial role in organic chemistry, providing a versatile tool for the formation of new carbon-carbon and carbon-heteroatom bonds.

SynonymBF3·THF, Boron trifluoride THF complex
CAS no.462-34-0
EINECS no.207-325-9
Molecular formulaBF· THF
Molecular weight139.91
Structure

MANUFACTURE

Boron trifluoride tetrahydrofuran complex is produced by purging of BF3 gas into tetrahydrofuran at controlled rate of temperature & pressure.

APPLICATIONS

Reactant or reagent involved in:
Deoxofluorination of alcohols and carbonyls
Synthesis of Methacrylate-PEG-Methacrylate-boron trifluoride self-doped gel polymer electrolytes
Hydroboration-oxidation of Divinylferrocene
Reagent involved in the synthesis of biologically active molecules such as:
NK-1 receptor antagonists
Complex polyketide natural products
Selective serotonin reuptake inhibitors
Used extensively as a polymerization initiator.

SPECIFICATIONS

TestUnitSpecification
AppearanceClear light brown liquid, darken on storage
Boron Trifluoride Content (By Fluorine)%Min 45.0
Boron Trifluoride Content (By Boron)%Min 45.0
Typical Property
Specific Gravitygm/ml1.25 – 1.27
Note: Not reported on COA

PACKING

35 Liter HDPE Jerrycan and 200 kg MS-HDPE composite drums

STORAGE

Store at room temperature in a well-ventilated place; Keep the container tightly closed.

REACH Status

Not registered.

No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Sodium Hyaluronate Ph. Eur.
Products in focus · 12/05/2026

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring glycosaminoglycan known for its exceptional ability to retain moisture, along with its viscoelastic and biocompatible properties, making it highly valuable across pharmaceutical, cosmetic, and biomedical applications.

READ MORE
In focus: Pyrazinamide Ph. Eur.
Products in focus · 05/05/2026

Pyrazinamide is a first-line antitubercular drug used in combination therapy for the treatment of tuberculosis (TB). It is a synthetic pyrazine derivative and acts as a prodrug, which is converted into its active form (pyrazinoic acid) inside Mycobacterium tuberculosis.

READ MORE
In focus: 6-Bromopyridine-2,3-diamine
Products in focus · 28/04/2026

6-Bromopyridine-2,3-diamine is a heterocyclic organic compound belonging to the class of substituted pyridines. It is used mainly as an intermediate in pharmaceuticals and agrochemicals.

READ MORE
In focus: MagnesiumTrisilicate BP (Trisilicalm)
Products in focus · 21/04/2026

Magnesium trisilicate is an inorganic compound commonly used in pharmaceutical and gastrointestinal (GI) preparations due to its dual action. It is usually produced as a white, odorless, fine powder. It helps bind toxins or irritants in the gastrointestinal tract and occasionally used in formulations for its stabilizing properties.

READ MORE
In focus: Choline Salicylate Solution
Products in focus · 14/04/2026

Choline salicylate is a salicylate salt formed from choline and salicylic acid. It is a non-steroidal anti-inflammatory agent (NSAID-type compound) mainly used for its analgesic, anti-inflammatory, and mild antiseptic properties. Unlike acetylated salicylates, it is less irritating to the gastric mucosa and is commonly used in topical oral preparations such as gels and mouth paints.

READ MORE
In focus: Tensyra™ N-10, (Octoxinol 10, Ph.Eur.)
Products in focus · 07/04/2026

TensyraTM N-10 (Octoxinol 10; tert-octyl phenyl ethoxylate) is a non-ionic surfactant known for its excellent solubilizing and membrane-permeabilizing properties. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.It readily breaks down biological membranes to lyse cells, solubilize proteins, and permeabilize cell membranes for assays.

READ MORE
In focus: Teprenone (Geranylgeranylacetone; GGA)
Products in focus · 31/03/2026

Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.

READ MORE
In focus: Ciclopirox Olamine Ph.Eur.
Products in focus · 24/03/2026

Ciclopirox Olamine (CPO)  is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.

READ MORE
In focus: N,N-Dimethylglycine sodium salt (DMG Na)
Products in focus · 17/03/2026

N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.

READ MORE