INTRODUCTION
Caffeine (anhydrous) is a naturally occurring methylxanthine derivative used as a CNS stimulant, to restore mental alertness and wakefulness in patients experiencing fatigue or drowsiness.
Manufacturing
Caffeine anhydrous is made from the seeds and leaves of green coffee plants. The word “anhydrous” means “without water.” After harvesting, caffeine is extracted from the plant matter and dehydrated. This produces a highly concentrated caffeine powder.
| Synonyms | Methyltheobromine 1,3,7-Trimethylxanthine |
| CAS no. | 58-08-2 |
| EINECS no. | 200-362-1 |
| Molecular formula | C8H10N4O2 |
| Molecular weight | 194.19 |
| Structure |  |
Applications
| Caffeine anhydrous is used as stimulant drug in |
|---|
| Food production |
| Beverage such as in coffee, tea, soda drink to stimulate the central nervous |
| Pharmaceutical |
| In Health and Personal care |
|---|
| Caffeine anhydrous is used as Fragrance Ingredient; Skin-Conditioning agent. |
| Primary short-term effects of Caffeine are: |
|---|
| Increasing resting heart rate |
| Psychostimulation |
| Constricting blood vessels |
| Dilating the bronchioles |
| Slightly increasing metabolic rate |
| Increasing urine production and gastric motility |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description | – | A white crystalline powder; sublimes readily |
| Solubility | – | Sparingly soluble in water, freely soluble in boiling water, slightly soluble in ethanol and in ether. It dissolves in concentrated solutions of alkali benzoates or salicylates. |
| Identification A | – | By IR absorption identical with Std. |
| Identification B | – | To Comply |
| Water | % | NMT 0.5 |
| Melting Range | °C | Between 235.0 – 237.5 after drying at 80°C for 4 hours |
| Residue on Ignition | % | NMT 0.1 |
| Arsenic | ppm | NMT 3.0 |
| Heavy Metals | % | NMT 0.001 |
| Readily Carbonizable Substances | – | The solution has no more color than matching Fluid D. |
| Residual solvents | – | To Comply |
| Other Alkaloids | – | No precipitate is formed |
| Chromatographic Purity – Any individual impurity | % | NMT 0.1 |
| Total impurity | % | NMT 0.1 |
| Assay | % | NLT 98.5 & NMT 101.0 on anhydrous basis |
STORAGE
Store in a cool, dry, well-ventilated area.
PACKING
25 kg drum.
REGISTRATION / CERTIFICATION
ISO, FSSAI, HALAL, KOSHER, GMP & US-DMF.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring glycosaminoglycan known for its exceptional ability to retain moisture, along with its viscoelastic and biocompatible properties, making it highly valuable across pharmaceutical, cosmetic, and biomedical applications.
Pyrazinamide is a first-line antitubercular drug used in combination therapy for the treatment of tuberculosis (TB). It is a synthetic pyrazine derivative and acts as a prodrug, which is converted into its active form (pyrazinoic acid) inside Mycobacterium tuberculosis.
6-Bromopyridine-2,3-diamine is a heterocyclic organic compound belonging to the class of substituted pyridines. It is used mainly as an intermediate in pharmaceuticals and agrochemicals.
Magnesium trisilicate is an inorganic compound commonly used in pharmaceutical and gastrointestinal (GI) preparations due to its dual action. It is usually produced as a white, odorless, fine powder. It helps bind toxins or irritants in the gastrointestinal tract and occasionally used in formulations for its stabilizing properties.
Choline salicylate is a salicylate salt formed from choline and salicylic acid. It is a non-steroidal anti-inflammatory agent (NSAID-type compound) mainly used for its analgesic, anti-inflammatory, and mild antiseptic properties. Unlike acetylated salicylates, it is less irritating to the gastric mucosa and is commonly used in topical oral preparations such as gels and mouth paints.
TensyraTM N-10 (Octoxinol 10; tert-octyl phenyl ethoxylate) is a non-ionic surfactant known for its excellent solubilizing and membrane-permeabilizing properties. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.It readily breaks down biological membranes to lyse cells, solubilize proteins, and permeabilize cell membranes for assays.
Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.
Ciclopirox Olamine (CPO) is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.
N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.