INTRODUCTION

Acryloyl chloride is an organic liquid from the class of acid chlorides.  It is a toxic and lachrymatic chemical that has a variety of applications in APIs, intermediates and polymers.

Manufacture

It is manufactured by chlorination of acrylic acid by phosphorus oxychloride.

Synonym2-Propenoyl chloride
Acrylic acid chloride
CAS #814-68-6
EINECS #212-399-0
Molecular formulaC3H3ClO
Molecular weight90.51
Structure

Applications

APIS

Poziotinib       (an anti-cancer drug)
Ibrutinib          (also an anti-cancer drug)

Intermediates

1-(2,3-Dihydro-1H-indol-1-yl)-2-propene-1-one
N-Isopropylacrylamide
N-Acryloxysuccinimide
1,4-Diacryloylpiperazine
Dodecyl acrylate

Polymers

Acrylic polymers
Poly(styrene-acryloyl chloride)copolymer
Acrylate-based conducting polymers

Others

Used as building block to introduce acrylic group in organic compounds

SPECIFICATIONS

TestUnitSpecifications
AppearanceColourless to pale yellow liquid
Identification by GCMain peak for sample solution should correspond to that of standard solution
Specific gravity at 30 deg cel1.112 – 1.116
Purity by GC%Min 98.00%
Acrylic acid by GC%Max 1.00%
3-Chloropropionyl chloride by GC%Max 0.50%
Total impurities by GC%Max 2.00%
BHT as stabilizerppmMax 500

STORAGE

Recommended storage temperature :  2° to 8°C

Shipped under temperature-controlled conditions

PACKING

100 kg UN-approved HDPE drum 

REACH Status

Not registered

ExSyn offers acryloyl chloride on commercial scales at refrigerated temperature and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Yttrium oxide
Products in focus · 04/08/2026

Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.

Read More
In focus:Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate
Products in focus · 28/07/2026

Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate is a fluorinated aliphatic hydroxy ester. The presence of the trifluoromethyl group imparts enhanced metabolic stability, lipophilicity, and unique physicochemical properties compared with non-fluorinated analogues. This compound is primarily used as a synthetic intermediate in pharmaceutical and agrochemical research.

Read More
In focus: 2-Chloro-1,1,1- trimethoxyethane
Products in focus · 21/07/2026

2-Chloro-1,1,1-trimethoxyethane is an organochlorine orthoester compound commonly used as a versatile synthetic intermediate in organic and pharmaceutical chemistry. It is a colorless to pale yellow liquid with good reactivity toward nucleophilic substitution and cyclization reactions, making it valuable in the preparation of heterocyclic and bioactive molecules.

Read More
In focus: Glycolaldehyde Dimer
Products in focus · 14/07/2026

Glycolaldehyde dimer is the cyclic dimeric form of glycolaldehyde, the simplest hydroxyaldehyde. Glycolaldehyde is often supplied as stable dimeric solid, commonly identified as 2,5-dihydroxy-1,4-dioxane.

Read More
In focus: N,N Diisopropylethylamine
Products in focus · 07/07/2026

N,N-Diisopropylethylamine (DIPEA), also known as Hünig’s Base, is a sterically hindered tertiary amine. It is a colorless liquid with a strong amine odor and is widely used as a low nucleophilic organic base in pharmaceutical, agrochemical, and fine chemical synthesis. Due to its bulky structure, DIPEA effectively scavenges acids without participating in unwanted side reactions.

Read More
In focus: Tris(2,4-ditert-butylphenyl) Phosphite
Products in focus · 30/06/2026

Tris(2,4-di-tert-butylphenyl) phosphite (TDPP) often recognized commercially as Irgafos 168 is a high-performance organophosphorus compound primarily utilized as secondary antioxidant and processing stabilizer. Its characteristic to undergo metallation reaction and provide a cost-effective synthetic processes allows it to be useful in biaryl coupling reactions.

Read More
In focus: Undecylenic acid, USP
Products in focus · 23/06/2026

Undecylenic acid is an unsaturated fatty acid naturally derived from castor oil. It is a colorless to pale yellow liquid with antifungal and antimicrobial properties. Chemically known as 10-undecenoic acid, it contains an 11-carbon chain with one double bond and is widely used in pharmaceuticals

Read More
In focus: 5-Nitro IsophthalicAcid (5-NIPA)
Products in focus · 16/06/2026

5-Nitro Isophthalic Acid (5-NIPA) is an aromatic organic compound derived from isophthalic acid. The presence of two carboxylic acid groups along with a nitro substituent at the 5-position makes it a valuable intermediate in the manufacture of fine chemicals, pharmaceuticals, dyes, pigments, and advanced materials.

Read More
In focus: Trichloroacetonitrile
Products in focus · 09/06/2026

Trichloroacetonitrile is a halogenated organic compound belonging to nitrile family. Its strong electrophilic character makes it a valuable intermediate in organic synthesis. It readily undergoes hydrolysis, particularly under acidic or basic conditions, yielding trichloroacetamide and related derivatives.

Read More