INTRODUCTION

Acryloyl chloride is an organic liquid from the class of acid chlorides.  It is a toxic and lachrymatic chemical that has a variety of applications in APIs, intermediates and polymers.

Manufacture

It is manufactured by chlorination of acrylic acid by phosphorus oxychloride.

Synonym2-Propenoyl chloride
Acrylic acid chloride
CAS #814-68-6
EINECS #212-399-0
Molecular formulaC3H3ClO
Molecular weight90.51
Structure

Applications

APIS

Poziotinib       (an anti-cancer drug)
Ibrutinib          (also an anti-cancer drug)

Intermediates

1-(2,3-Dihydro-1H-indol-1-yl)-2-propene-1-one
N-Isopropylacrylamide
N-Acryloxysuccinimide
1,4-Diacryloylpiperazine
Dodecyl acrylate

Polymers

Acrylic polymers
Poly(styrene-acryloyl chloride)copolymer
Acrylate-based conducting polymers

Others

Used as building block to introduce acrylic group in organic compounds

SPECIFICATIONS

TestUnitSpecifications
Appearance–Colourless to pale yellow liquid
Identification by GC–Main peak for sample solution should correspond to that of standard solution
Specific gravity at 30 deg cel–1.112 – 1.116
Purity by GC%Min 98.00%
Acrylic acid by GC%Max 1.00%
3-Chloropropionyl chloride by GC%Max 0.50%
Total impurities by GC%Max 2.00%
BHT as stabilizerppmMax 500

STORAGE

Recommended storage temperature :  2° to 8°C

Shipped under temperature-controlled conditions

PACKING

100 kg UN-approved HDPE drum 

REACH Status

Not registered

ExSyn offers acryloyl chloride on commercial scales at refrigerated temperature and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Diacetone Alcohol
Products in focus · 29/09/2026

Diacetone Alcohol (DAA) is an aliphatic hydroxy ketone produced through the base-catalysed aldol addition of two acetone molecules. It contains both ketone and tertiary hydroxyl functionalities, offering excellent solvency and chemical reactivity.

As a high-boiling oxygenated solvent and valuable chemical intermediate, DAA finds broad application in paints and coatings, printing inks, adhesives, industrial cleaning, cosmetics, and textiles. It is also used as an intermediate in the production of mesityl oxide and MIBK. (4-methylpentan-2-one).

Read More
In focus: Kojic Acid
Products in focus · 22/09/2026

Kojic acid is a natural fungal metabolite produced through natural fermentation of carbohydrates. It works primarily as a tyrosinase inhibitor, suppressing melanin production to help reduce dark spots and even out skin tone. It also delivers antioxidant benefits, neutralizing free radicals and protecting skin cells from oxidative stress. With its naturally weak acidic profile, kojic acid is a multifunctional ingredient suited for brightening and protective skincare formulations.

Read More
In focus: (S)-Oxetan-2-yl-methanamine
Products in focus · 15/09/2026

(S)-Oxetan-2-yl-methanamine is a chiral oxetane-containing primary amine. The compound features a strained four-membered oxetane ring and an aminomethyl substituent, making it a valuable building block in modern medicinal chemistry. Due to its unique physicochemical properties, including increased polarity and metabolic stability compared with conventional alkyl groups, it is widely employed as an advanced pharmaceutical intermediate in drug discovery and development programs.

Read More
In focus: Guanidine Carbonate
Products in focus · 08/09/2026

Guanidine carbonate is a white, crystalline, water-soluble compound with an alkaline and ionic nature. Composed of guanidinium cations and carbonate anions, it offers chemical stability, buffering capacity, and good formulation compatibility. In textile applications, it is used in formulations and fabric treatments for its thickening, softening, lubricating, anti-static, and flame-retardant properties, contributing to improved fabric finish and performance.

Read More
In focus: Tin(II) sulfide
Products in focus · 01/09/2026

Tin(II) sulfide (SnS) has emerged as a safe and sustainable semiconductor owing to its non-toxicity, low cost, and natural abundance. It has attracted significant interest for solar energy conversion in thin-film photovoltaic devices because of its suitable band gap, which is approximately 1.3 eV in the orthorhombic phase and 1.5-1.7 eV in the cubic phase. In addition to photovoltaic applications, SnS is used in solid-state lubricants, near-infrared detectors, Lithium-ion batteries, and various sensing devices.

Read More
In focus: Nikethamide BP (N,N-Diethylnicotamide)
Products in focus · 25/08/2026

Nikethamide is a synthetic organic compound derived from nicotinic acid (vitamin B₃). It consists of a pyridine ring linked to a diethyl amide functional group and belongs to the class of pyridine amide derivatives.

Read More
In focus: (2-Methoxy-1-methyl-2-oxoethyl)triphenylphosphoniumbromide
Products in focus · 18/08/2026

(2-Methoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide is a stabilized phosphonium salt widely used as an intermediate in organic synthesis. Due to presence of an ester group, the compound generates a stabilized ylide that is particularly useful for synthesizing α, β-unsaturated esters, valuable intermediates in pharmaceuticals, agrochemicals, fragrances, and fine chemicals.

Read More
In focus: p-tert-butylphenol (PTBP)
Products in focus · 11/08/2026

p-tert-Butylphenol (PTBP), is an aromatic organic compound consists of a phenol ring substituted with a tert-butyl group at the para (4-) position, giving it improved thermal stability and hydrophobic properties compared to phenol. PTBP features significant hydrogen bonding capabilities, which enhance its solubility in organic solvents. PTBP is used primarily as an intermediate in the manufacturing of polycarbonate plastics, phenolic resins, and epoxy resins.

Read More
In focus: Yttrium oxide
Products in focus · 04/08/2026

Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.

Read More