INTRODUCTION
Triphenylphosphine is a common organophosphorus compound that is frequently abbreviated as PPh3 or Ph3P. It is widely used in organic and organometallic compound synthesis because it is an effective reducing agent as well as a neutral ligand. At room temperature, PPh3 crystals are relatively air-stable and colourless.
MANUFACTURE
The industrial synthesis involves the reaction between phosphorus trichloride, chlorobenzene, and sodium.
| Synonym | Triphenylphosphane,Phosphorus triphenyl |
| CAS no. | 603-35-0 |
| EINECS no. | 210-036-0 |
| Molecular formula | C18H15P |
| Molecular weight | 262.29 g/mol |
| Structure |  |
| APPLICATIONS |
|---|
| Triphenylphosphine is used in the synthesis of Chlorambucil, which has been shown to be cytotoxic in breast and pancreatic cancers. |
| It is also used to make -Tocopherol analogues for monitoring antioxidant status. |
| Used in the synthesis of Vitamin D2, Vitamin A, Clindamycin, and other drugs. |
| Also, used in a variety of applications, including sensitizers, heat stabilizers, light stabilizers, antioxidants, flame retardants, antistatic agents, rubber antiozonants, and analytical reagents. |
| The Wittig reaction, which converts aldehydes and ketones to alkenes, was Ph3P’s first significant use in organic synthesis. |
| Triphenylphosphine is also used as a transition metal-ligand in olefin polymerizations and in the Suzuki, Mitsunobu, and Appel reactions. |
| In homogeneous catalysis, triphenylphosphine is a standard ligand. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description | – | A white to off white crystalline powder or flakes |
| Solubility | – | Soluble in toluene |
| Melting range | °C | 78.0 to 83.0 |
| Loss on drying | % w/w | Not more than 0.5 |
| Assay (by chemical) | % | Not less than 99.0 |
PACKING
25 kg HDPE bag.
STORAGE
Store in a dry and well-ventilated place.
REACH
Not registered.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Magnesium trisilicate is an inorganic compound commonly used in pharmaceutical and gastrointestinal (GI) preparations due to its dual action. It is usually produced as a white, odorless, fine powder. It helps bind toxins or irritants in the gastrointestinal tract and occasionally used in formulations for its stabilizing properties.
Choline salicylate is a salicylate salt formed from choline and salicylic acid. It is a non-steroidal anti-inflammatory agent (NSAID-type compound) mainly used for its analgesic, anti-inflammatory, and mild antiseptic properties. Unlike acetylated salicylates, it is less irritating to the gastric mucosa and is commonly used in topical oral preparations such as gels and mouth paints.
TensyraTM N-10 (Octoxinol 10; tert-octyl phenyl ethoxylate) is a non-ionic surfactant known for its excellent solubilizing and membrane-permeabilizing properties. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.It readily breaks down biological membranes to lyse cells, solubilize proteins, and permeabilize cell membranes for assays.
Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.
Ciclopirox Olamine (CPO) is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.
N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.
Blown Castor Oil (15-17 Poise) is a modified grade of Castor oil. The “15-17 Poise” specification refers to its viscosity range, indicating a medium-viscosity blown oil suitable for industrial applications requiring improved body, tackiness, and elasticity compared to regular castor oil.
Dimethylaminoethanol (DMAE) is a is a tertiary amine that is ethanolamine having two N-methyl substituents. It is clear & colourless to pale yellow liquid with ammoniacal odor. DMAE is stable at room temperature and is completely miscible with water as well as organic solvents such as alcohols and ethers. It decomposes at high temperatures. It is a versatile chemical intermediate primarily used as a curing agent for polyurethane foams and epoxy resins.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.