INTRODUCTION
Tetrahydrocurcumin (THC) is a colorless hydrogenated product derived from the yellow curcumins, (the biologically active principles from the rhizomes of Curcuma longa), function as efficient antioxidant compounds. THC exhibit many of the same physiologic and pharmacological activities as curcumins and in some systems may exert greater antioxidant activity than curcumins. The superior antioxidant property of THC, combined with the lack of yellow color, render this product useful in achromatic food and cosmetic applications that currently employ conventional synthetic antioxidants.
| Synonyms | Tetrahydrodiferuloylmethane 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione |
| CAS no. | 36062-04-1 |
| EINECS no. | 609-201-3 |
| Molecular formula | C21H24O6 |
| Molecular weight | 372.41 |
| Structure |  |
Applications
Widely used in Dietary Supplements, Nutritional Products & Cosmetics.
| Some key areas |
|---|
| Standardized Hydro curcuminoids have scientifically proven health benefits in various diseases like amyloid protein related diseases, cancer related diseases, multiples sclerosis, multiple myeloma, cystic fibrosis, prion diseases and other autoimmune diseases |
| As anti-oxidants |
| As dyes for imaging |
| As food additive |
| For cosmetic and anti-aging applications to reduce inflammation |
| As skin lightening formulation and against melanoma |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| PHYSICAL | ||
| Description | – | Off White to Cream color powder |
| Identification | – | To comply by HPLC |
| Loss on drying | % w/w | NMT 2.0 |
| Residue on Ignition | % w/w | NMT 2.0 |
| Tapped Bulk density | g/ml | 0.3 – 0.8 |
| Solubility | – | Soluble in Acetone |
| Sieve test (passes through) #40 mesh | % | NLT 90.0 |
| CHEMICAL | ||
| Assay – Content of Hydrocurcuminoids (by HPLC) (on dry basis) | % w/w | NLT 95.0 |
| OTHERS | ||
| Lead (Pb) | ppm | NMT 5.0 (by ICP-OES) |
| Arsenic (As) | ppm | NMT 1.0 (by ICP-OES) |
| Cadmium (Cd) | ppm | NMT 0.3 (by ICP-OES) |
| Mercury (Hg) | ppm | NMT 0.1 (by ICP-OES) |
| Residual Solvents | – | Should comply by ICH/USP |
| Residual Pesticides | – | Should comply by ICH/USP |
STORAGE
The product is stored at ambient temperature.
PACKING
25 kg drum.
FDA status
Facility is registered with US-FDA.
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