INTRODUCTION
Dimethyl sulfoxide, popularly knowns by its acronym DMSO, is an organosulfur compound. It is an aprotic polar solvent, a mild oxidant, and a common ligand in co-ordination chemistry. Its versatility lies in the fact that it can dissolve polar as well as non-polar solutes and hence it is a special solvent in organic syntheses. Its utility is further due to its low cost, low toxicity, and stability.
Manufacture
It is manufactured by oxidation of dimethyl sulfide by either oxygen or nitrogen dioxide.
| Synonyms | Dimethyl sulfur oxide Methylsulfinylmethane |
| CAS no. | 67-68-5 |
| EINECS no. | 200-664-3 |
| Molecular formula | C2H6OS |
| Molecular weight | 78.13 |
| Structure |  |
Applications in Medicine
| as a solvent in in vivo and in vitro drug testing |
| used as topical analgesic |
Applications in Pharma
| DMSO is used as a solvent in production of: |
|---|
| Minoxidil, used as an antihypertensive and in dermatological preparations |
| Oxolinic acid, a quinolone antibiotic |
Applications in Intermediates
| It is a preferred solvent to manufacture intermediate products such as: |
|---|
| 1,2-Methylenedioxybenzene from resorcinol |
| 3,4-Methylenedioxyaniline |
| N-Ethyl-3,4-methylenedioxyanilline |
Generic Applications in Organic Syntheses
| DMSO-induced dehydrogenation oxidations such as Swern Oxidation and Pfitzner Moffatt Oxidation |
| Oxygen-adding oxidation such as Komblum Oxidation |
| DMSO acts as source to incorporate methyl, methylsulfonyl, and methylthio groups in substrate molecules |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Crystallization point | °C | Min 18.10 |
| Acid value | mg KOH/g | Max 0.03 |
| Transmittance at 400nm | % | Min 96.0 |
| Refractive Index at 20 °C | – | 1.4775 – 1.4790 |
| Moisture | % | Max 0.1 |
| Purity | % | Min 99.90 |
STORAGE
The product is stored at ambient temperature
PACKING
225 kg MS drum
REACH Status
Not registered yet
ExSyn offers DMSO on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Sodium Decane-1-Sulfonate is a surfactant with a long hydrophobic tail and hydrophilic sulfonate group, used to reduce surface tension and stabilize emulsions. It is commonly used in detergents, personal care products, and chemical formulations to enhance solubility and improve performance.
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. It is a multifunctional Oil-in- Water Emulsifier that is a very versatile and multifunctional non-ionic surfactant used as fragrance builder and fragrance solubilizer,emulsifier in cosmetics and as pharmaceutical aid.
Trifluoroacetic anhydride is an organic liquid that belongs to the category of fluorochemicals. It is an anhydride of trifluoroacetic acid and has uses in APIs, intermediates, and agrochemicals. It is also a building block to introduce trifluoroacetyl group in organic moieties.
Benzene-d6 is a deuterated form of benzene, where hydrogen atoms are replaced by deuterium, making it ideal for use as a solvent in NMR spectroscopy. It is widely employed in chemical, pharmaceutical, and environmental research for isotopic labeling and reaction mechanism studies.
Pyridinium tribromide, an organic solid from the category of heterocyclic halides, is a highly efficient and selective bromination agent in organic syntheses. It is also used in production of APIs and intermediates.
Pyrophosphoryl Tetrachloride is a colorless fuming corrosive liquid .It consists of a pyrophosphate (a molecule with a P-O-P bond) group, where one phosphorus atom is bonded to four chlorine atoms and the other is bonded to three chlorine atoms.
It is a reactive chemical compound and should be handled with care. Commonly used in the synthesis of other phosphorus-containing compounds and as a chlorinating agent in organic chemistry
Trifluoroacetic acid (TFA) is widely used in organic synthesis as a solvent, catalyst, and reagent, owing to its reactivity and stability under adverse conditions. It is considered as one of the most economical fluorinated building blocks.
Acryloyl chloride is an organic liquid from the class of acid chlorides. It is a toxic and lachrymatic chemical that has a variety of applications in APIs, intermediates and polymers.
Triton X-100 is a widely used non-ionic surfactant and emulsifier that effectively solubilizes powders and proteins. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.