INTRODUCTION
Dimethyl sulfoxide, popularly knowns by its acronym DMSO, is an organosulfur compound. It is an aprotic polar solvent, a mild oxidant, and a common ligand in co-ordination chemistry. Its versatility lies in the fact that it can dissolve polar as well as non-polar solutes and hence it is a special solvent in organic syntheses. Its utility is further due to its low cost, low toxicity, and stability.
Manufacture
It is manufactured by oxidation of dimethyl sulfide by either oxygen or nitrogen dioxide.
| Synonyms | Dimethyl sulfur oxide Methylsulfinylmethane |
| CAS no. | 67-68-5 |
| EINECS no. | 200-664-3 |
| Molecular formula | C2H6OS |
| Molecular weight | 78.13 |
| Structure |  |
Applications in Medicine
| as a solvent in in vivo and in vitro drug testing |
| used as topical analgesic |
Applications in Pharma
| DMSO is used as a solvent in production of: |
|---|
| Minoxidil, used as an antihypertensive and in dermatological preparations |
| Oxolinic acid, a quinolone antibiotic |
Applications in Intermediates
| It is a preferred solvent to manufacture intermediate products such as: |
|---|
| 1,2-Methylenedioxybenzene from resorcinol |
| 3,4-Methylenedioxyaniline |
| N-Ethyl-3,4-methylenedioxyanilline |
Generic Applications in Organic Syntheses
| DMSO-induced dehydrogenation oxidations such as Swern Oxidation and Pfitzner Moffatt Oxidation |
| Oxygen-adding oxidation such as Komblum Oxidation |
| DMSO acts as source to incorporate methyl, methylsulfonyl, and methylthio groups in substrate molecules |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Crystallization point | °C | Min 18.10 |
| Acid value | mg KOH/g | Max 0.03 |
| Transmittance at 400nm | % | Min 96.0 |
| Refractive Index at 20 °C | – | 1.4775 – 1.4790 |
| Moisture | % | Max 0.1 |
| Purity | % | Min 99.90 |
STORAGE
The product is stored at ambient temperature
PACKING
225 kg MS drum
REACH Status
Not registered yet
ExSyn offers DMSO on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
L-Alpha glycerylphosphorylcholine (alpha-GPC or choline alfoscerate) is a choline-containing phospholipid. When ingested, alpha-GPC is metabolized into choline and glycerol-1-phosphate. Choline is a precursor of acetylcholine, a neurotransmitter involved in memory, attention, and skeletal muscle contraction.
3,3,3-Trifluoropropanol is a colorless liquid that is consumed in manufacture of value-added intermediates. This apart, the halogenated alcohol is also cited to have applications in other industry verticals. It also finds uses in proteomic research and in agrochemicals.
Calcium Gluconate is the calcium salt of gluconic acid, an oxidation product of glucose, and contains 9.3% calcium, which is about one-third of the calcium in the strength of calcium chloride. It is an ingredient found in a variety of supplements and vitamins and is used to lower potassium in the blood.
2-Amino-6-fluorobenzonitrile is a powder form chemical that has multiple uses ranging from medicine to intermediates to APIs. The structure of the compound depicts that it has an active fluorine atom in o-position to the nitrile group and this renders the molecule reactive. It thus participates in many synthetic processes.
Sodium Alginate is a linear polysaccharide derivative of alginic acid processed from brown algae. The conversion of alginic acid to sodium alginate allows its solubility in water, which assists its extraction. Sodium Alginate is used as a hydrocolloid in various applications such as food manufacturing and pharmaceuticals, as an emulsifier in textiles and cosmetics industries and in dentistry to make molds.
Chromium hydroxide, a gelatinous, polymeric inorganic powder, is amphoteric in nature. It reacts as an acid as well as a base. On heating, it decomposes to chromic oxide. The molecule is largely used in cosmetics and tanning industries.
Magnesium trisilicate is an inorganic compound that is used as a food additive. The additive is frequently used by fast food chains to absorb fatty acids and extract impurities formed while frying edible oils. It has good acid neutralizing properties.
1,3-Dihyrdoxyacetone is a hygroscopic, white powder with a minty odor. It is abundantly found in nature as derivative of starch and is an intermediate product of fructose metabolism. Acronymed as DHA, it is at large used in the cosmetic industry.
3-Chloroperoxybenzoic acid (MCPBA) is a peroxycarboxylic acid. A white solid, it is used widely as an oxidant in organic synthesis. MCPBA is often preferred to other peroxy acids because of its relative ease of handling.