INTRODUCTION
(S)-(+)-Glycidyl p-toluenesulphonates is an organic chemical in the class of epoxide and it is a chiral molecule. Its reactivity is due to presence of active epoxide moiety and thus it undergoes various transformation reactions leading to syntheses of chiral intermediates and biologically active products.
Manufacture
The chiral compound is manufactured by the reaction of tosyl chloride with S-glycidol. The resultant ester is treated with a strong base to obtain the desired product.
| Synonym | (2S)-(+)-Glycidyl tosylate (S)-Glycidyl tosylate |
| CAS no. | 70987-78-9 |
| EINECS no. | 417-210-7 |
| Molecular formula | C10H12O4S |
| Molecular weight | 228.26 |
| Structure |  |
| Applications |
|---|
| Enantioselective synthesis of 4-acetyl-3-hydroxymethyl-3,4-dihydro-2H-pyrido [3,3-b] oxazine |
| In synthesis of 1-O-hexadecyl-2-O-benzyl-sn-glycerol 3-O-p-toluenesuplhonte |
| As a reagent in production of chiral molecules and chiral intermediates for APIs such as: # (S)-2-Oxiranylanisole # S)-2-((3-Chlorophenoxy)methyl)oxirane |
| As building block for polymers and other materials |
| In synthesis of peptides, peptidomimetics, and other biological active substances |
| As an intermediate to synthesize neurochemicals |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | White to off-white crystalline powder |
| Specific rotation, (C=2.75 CHCl3) | – | +17 to +19 |
| LOD | % | Max 1.0 |
| Melting point | °C | 45.0 – 48.0 |
| Assay by GC | % | Min 98.0 |
| Enantiomeric excess by HPLC | ee% | Min 99.0 |
STORAGE
2 to 8 °C
PACKING
25 kg drum
REACH Status
Not registered yet
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
INTRODUCTION Guanosine 5’-diphosphate disodium salt (GDP·Na2) is a purine nucleoside diphosphate that plays a crucial role in various biochemical processes. It is a nucleoside consisting of the base guanine and the sugar riboseIt has two phosphate groups, which affects its function and interactions with enzymes. It is a salt form where two sodium ions are […]
INTRODUCTION Rheological additives are essential components in paint formulations used to control the flow and viscosity of the paint. Modified rheological additives are advanced formulations of traditional rheological additives. They are designed to offer improved performance, versatility, or specific functional properties in applications like paints, coatings etc. Synonym Alkyl quaternary ammonium bentonite CAS no. 68153-34-4 […]
Curcumin, a compound found in turmeric, is known for its anti-inflammatory and antioxidant properties. Introducing 95% curcumin in both human and animal applications involves understanding its high potency, ensuring effective delivery and absorption
Titanium Dioxide (TiO₂) is one of the most important and widely used white pigments in the world. It’s a versatile compound found in an array of products across various industries. Its exceptional properties make it an essential ingredient in everything from paints and coatings to adhesives and cosmetics. TiO₂ exists in two primary grades: Anatase and Rutile.
Hydriodic acid is a strong acid solution of hydrogen iodide in water at nominal concentrations of 47% and 57%. Its stabilized formulation ensures consistent quality and reliability in various applications. This compound often appears as a colorless to pale yellow liquid with a sharp, pungent odor, characteristic of hydrogen halides.
n-Propylamine, known as propylamine in trade, is a versatile primary amine with a lone pair of electrons on nitrogen atom. It makes the amino group reactive and the amine thus undergoes chiefly nucleophilic substitution reactions with substrate.
Iodine is anon-metallic, dark-grey/purple-black, lustrous, solid element. It is the heaviest and the rarest of stable halogens that can be found on the crust of earth.About fifty percent of all iodine produced and manufactured worldwide is used to form Organoiodine compounds. Iodine is an important element for many health-sustaining processes and essential for human thyroid health.
The product, acronymed Oct-NBE, is an organic compound with a cyclic ring system and a 8-membered hydrophobic chain. The structure renders the chemical special properties leading to its applications in diverse fields.
Nicotine is a hygroscopic, colorless to slight yellow, oily liquid, that is readily soluble in alcohol, ether or light petroleum. It is widely used recreationally as a stimulant and anxiolytic.