INTRODUCTION

(S)-(+)-Glycidyl p-toluenesulphonates is an organic chemical in the class of epoxide and it is a chiral molecule. Its reactivity is due to presence of active epoxide moiety and thus it undergoes various transformation reactions leading to syntheses of chiral intermediates and biologically active products.

Manufacture
The chiral compound is manufactured by the reaction of tosyl chloride with S-glycidol. The resultant ester is treated with a strong base to obtain the desired product.

Synonym(2S)-(+)-Glycidyl tosylate
(S)-Glycidyl tosylate
CAS no.70987-78-9
EINECS no.417-210-7
Molecular formulaC10H12O4S
Molecular weight228.26
Structure
Applications
Enantioselective synthesis of 4-acetyl-3-hydroxymethyl-3,4-dihydro-2H-pyrido [3,3-b] oxazine
In synthesis of 1-O-hexadecyl-2-O-benzyl-sn-glycerol 3-O-p-toluenesuplhonte
As a reagent in production of chiral molecules and chiral intermediates for APIs such as:
# (S)-2-Oxiranylanisole
# S)-2-((3-Chlorophenoxy)methyl)oxirane
As building block for polymers and other materials
In synthesis of peptides, peptidomimetics, and other biological active substances
As an intermediate to synthesize neurochemicals

SPECIFICATIONS

TestUnitSpecification
AppearanceWhite to off-white crystalline powder
Specific rotation, (C=2.75 CHCl3)+17 to +19
LOD%Max 1.0
Melting point°C45.0 – 48.0
Assay by GC%Min 98.0
Enantiomeric excess by HPLCee%Min 99.0

STORAGE
2 to 8 °C

PACKING
25 kg drum

REACH Status
Not registered yet

No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Lycopene
Products in focus · 15/07/2025

Fungal Lycopene is an acyclic carotene belonging to a large group of naturally-occurring pigments known as carotenoids. It contains at least 90% of all-trans-lycopene and minor quantities of 13-cis-lycopene and β- and γ-carotene. It is used as an intermediate in the biosynthetic pathway of β-carotene. Its role in the pharmaceutical and food industries stems from its demonstrated health benefits—such as anticancer and cardiovascular protection—alongside its widespread use as a natural food colorant.

READ MORE
In focus: Methyl Tertiary Butyl Ether (MTBE) High Purity
Products in focus · 08/07/2025

Methyl Tertiary Butyl Ether (MTBE) is a high-purity chemical compound, typically exceeding 99.8% purity, widely valued for its use as a solvent and as an additive in fuels. It finds applications in pharmaceutical manufacturing, agrochemical and polymer production, as well as a solvent in extraction and recrystallization processes.

READ MORE
In focus: Berberine Hydrochloride
Products in focus · 01/07/2025

Berberine Hydrochloride is a yellow isoquinoline alkaloid extracted from various plants such as Berberis aristata, Coptis chinensis (Chinese goldthread), and Hydrastis canadensis (goldenseal). Berberine offered by ExSyn is from Berberis aristata. It is most commonly used in its hydrochloride salt form due to its better solubility and bioavailability. It is widely known for its antimicrobial, anti-inflammatory, and metabolic regulatory properties, and has gained popularity in nutraceutical and pharmaceutical industries.

READ MORE
In focus: Bromobenzene – d5
Products in focus · 24/06/2025

Bromobenzene-d5 is a perdeuterated form of bromobenzene(C6H5Br),  meaning all five hydrogen atoms in the benzene ring are replaced with deuterium (a stable isotope of hydrogen with one proton and one neutron). It is used as a stable isotope labeled compound, primarily in electronics industry, specifically in the production of OLED displays, in research applications, particularly in NMR spectroscopy and as a raw material in organic synthesis.

READ MORE
In focus: 2,2,2-Trifluoroethyl Methacrylate (Stabilized with MEHQ)
Products in focus · 17/06/2025

2,2,2-Trifluoroethyl Methacrylate (TFEMA) is a specialty methacrylate monomer featuring a trifluoromethyl (-CF₃) group. It is a colorless, highly reactive liquid stabilized with MEHQ. This compound is widely used in the synthesis of high-performance fluorinated polymers and TFEMA a valuable component in advanced applications such as protective coatings, optical materials, adhesives, electronics, and biomedical devices.

READ MORE
In focus: Ginkgo Biloba Extract 24%
Products in focus · 10/06/2025

Ginkgo Biloba 24% extract is a standardized herbal formulation derived from the leaves of the Ginkgo biloba tree, one of the oldest living tree species. The “24%” typically refers to the content of flavone glycosides, while the product may also contain 6% terpene lactones. These active constituents are responsible for its medicinal properties.

READ MORE
In focus: 1,3-Dibromopropane
Products in focus · 03/06/2025

1,3-Dibromopropane is an organobromine compound.  A bifunctional alkyl halide, it has two bromine leaving groups that can participate in substitution or elimination reactions. It is widely used as a an intermediate in production of wide range of products including pharmaceuticals, insecticides, quaternary Ammonium compounds, flavouring agents ,fragrances and in polymer chemistry.

READ MORE
In focus: Tributyltin Hydride (Stabilized with BHT)
Products in focus · 27/05/2025

Tributyltin Hydride (TBT-H) stabilized with BHT (butylated hydroxytoluene) is a tin-based organometallic compound commonly used in organic synthesis, especially in radical reactions. It is air-sensitive and decomposes to tributyltin oxide in  presence of oxygen and light. It works by donating a hydrogen radical (H·) to a carbon radical intermediate.

READ MORE
In focus: Sodium Chloro Acetate
Products in focus · 20/05/2025

Sodium chloroacetate (chemical formula: CH₂ClCO₂Na) is a white, crystalline solid that is highly soluble in water and organic solvents like ethanol, chloroform, ether, and benzene. It is the sodium salt of chloroacetic acid and is prepared by treating chloroacetic acid with sodium carbonate

READ MORE