Pyrophosphoryl chloride is colourless to pale yellow liquid, reasonably easy to handle. It reacts violently with water & miscible with most organic solvents.
It is used in pharmaceutical and other organic synthesis, as laser materials and electronic components.
Pyrophosphoryl chloride is prepared by reacting dichlorophosphoric acid, or a mixture containing the acid with phosphorus pentachloride in the absence of water.
|Pyrophosphoryl chloride serves as a reductive chlorination reagent used in the synthesis of quetiapine.|
|It acts as a phosphorylating agent involved in nucleoside synthesis.|
|It plays an important role in Vilsmeier formylation and glyoxylation reactions.|
|Diphosphoryl chloride is used in the synthesis of potent and orally bioavailable tricyclic CGRP receptor antagonists.|
|Also used in the synthesis of transition state analogue inhbitors of inosine monophosphate.|
|Characteristics||–||Colorless, smoking, corrosive liquid|
|Specific gravity||–||1.80 – 1.82|
|Assay by Chloride||%||Min 99.0|
|Assay by Acidimetric||%||Min 99.0|
Moisture Sensitive. Air Sensitive. Store under Nitrogen. Ambient temperatures.
40 kg UN approved carboys.
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