INTRODUCTION
Permethrin is an insecticide in the pyrethroid chemical family. Being a neurotoxic synthetic pyrethroid, it acts on the nervous system of insects. It interferes with sodium channels to disrupt the function of neurons and causes muscles to spasm, culminating in paralysis and death of arthropod. It affects sodium transport across the neuronal membranes in arthropods, thus causing depolarization. It is a mixture of a cis -trans isomer.
As an antiparasitic active ingredient, Permethrin finds an increasing use in veterinary and human medicines. It is used in livestock and pets against external parasites (lice, mites, fleas, flies, ticks, etc.). It acts as a mild repellent. It has a role as a pyrethroid ester insecticide, a pyrethroid ester acaricide, an ecto-parasiticide and a scabicide. It is a member of cyclopropanes and a cyclopropane-carboxylate ester.
| Synonyms | 3- (2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid (3 –phenoxyphenyl)-methyl ester; 3-phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| CAS no. | 52645-53-1 |
| EINECS no. | 258-067-9 |
| Molecular formula | C21H20Cl2O3 |
APPLICATIONS
Permethrin is used in agricultural, textile, food and pharma industries. Some of the key applications where it is used are:
Insecticide
| to protect crops & to kill livestock parasites |
| on structures and buildings, including livestock housing and food-handling establishments. Permethrin can also be used in numerous residential sites, both indoor and outdoor and on pets |
| to prevent insect attack on woollen products |
| in aircraft disinfection |
Insect repellant
| as a personal protective measure, permethrin is applied to clothing. It is a cloth impregnant, notably in mosquito nets and field wear. |
| while permethrin may be marketed as an insect repellent, it doesn’t prevent insects from landing. Instead, it works by incapacitating or killing insects before they can bite. |
| in pet flea preventive collars or treatment (safe for use on dogs but not cats) |
| in timber treatment |
Medicinal
| available for topical use as a cream or lotion |
| used for the treatment and prevention in exposed individuals of head lice |
| used as a medication in the treatment of scabies in humans and animals |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description & Solubility | – | Yellow brownish coloured liquid which may solidify on standing or at lower temperature. Soluble in alcohol (96 % w/v) , Acetone, ether and hydrocarbons (Toluene) |
| Identification by IR | – | IR Spectrum exhibits maxima which are only at the same wave number as those in “Reference Spectrum of Permethrin- Working Standard” / CRS |
| Identification by HPLC | – | Retention time of Permethrin matches with retention time of standard in the assay test |
| Loss on Drying | % | NMT 0.2 |
| Sulphated Ash | % | NMT 0.2 |
| Assay by HPLC (on dried Basis) | % | 98.0 – 101.0 |
| Trans Isomer | % | 73.0 – 77.0 |
| Cis Isomer | % | 23.0 – 27.0 |
PACKAGING OPTIONS
25 Kg HDPE Drums
STORAGE
Store in a sheltered place away from sources of heat and moisture
Permethrin offered by ExSyn is WHO-GMP certified. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Tert-Amyl Alcohol (TAA) also known as 2-Methyl-2-butanol, is a branched-chain alcohol. It is a colorless, flammable liquid with a mild alcoholic odor and moderate water solubility. Due to its unique structural properties, it is widely used as basic organic chemical in synthetic fragrances, pharmaceuticals and pigment industries.
Lithium orotate is a compound consisting of lithium, an alkali metal, and orotic acid, a natural substance involved in nucleic acid metabolism. It is a popular dietary supplement due to its potential neuroprotective and mood-stabilizing effects.
Quinuclidinone Hydrochloride is a derivative of bicyclic amine quinuclidine. The hydrochloride form of quinuclidinone is the salt form, often used for its stability in different reactions. Quinuclidinone Hydrochloride is typically used as an intermediate in the synthesis of various pharmaceuticals and other chemical products.
Potassium benzoate (E212), the potassium salt of benzoic acid, is a food preservative used to prevent the growth of mold, yeast and some bacteria. It works best in low-pH products, below 4.5, where it exists as benzoic acid.
n-Hexyllithium in hexane solution (HxLi) is an organolithium compound primarily used in organic synthesis as a strong base, alkylating agent, and lithiation reagent. It is particularly effective in the deprotonation of weakly acidic compounds. Handling n-Hexyllithium requires strict safety precautions due to its highly reactive nature, particularly due to its sensitivity to moisture, air, and heat.
2,4-Dichlorobenzyl alcohol (DCBA) is a member of the class of Benzyl alcohols in which the hydrogens at positions 2 and 4 are replaced by chlorines.
Its effectiveness against a broad spectrum of pathogens makes it a valuable ingredient in antiseptic products.
Ethylhexylglycerin is typically a clear, colorless liquid used in personal care products, as a preservative and a conditioning agent. It’s approved for use in cosmetics by regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Union (EU).
N-acetylsulfanilyl chloride is a white coloured powder, soluble in organic solvents and slightly soluble in water. It is a versatile chemical compound that has numerous applications in industries, such as Agro and Pharmaceuticals.
Fir Needle Essential Oil is obtained from the fir needles of the Siberian fir tree Abies sibirica, belonging to the plant family of Pinaceae. The oil has a fresh, green, woody, and balsamic fragrance due to which it is generally used as a fragrance ingredient in soaps and perfumes.