INTRODUCTION
Permethrin is an insecticide in the pyrethroid chemical family. Being a neurotoxic synthetic pyrethroid, it acts on the nervous system of insects. It interferes with sodium channels to disrupt the function of neurons and causes muscles to spasm, culminating in paralysis and death of arthropod. It affects sodium transport across the neuronal membranes in arthropods, thus causing depolarization. It is a mixture of a cis -trans isomer.
As an antiparasitic active ingredient, Permethrin finds an increasing use in veterinary and human medicines. It is used in livestock and pets against external parasites (lice, mites, fleas, flies, ticks, etc.). It acts as a mild repellent. It has a role as a pyrethroid ester insecticide, a pyrethroid ester acaricide, an ecto-parasiticide and a scabicide. It is a member of cyclopropanes and a cyclopropane-carboxylate ester.
| Synonyms | 3- (2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid (3 –phenoxyphenyl)-methyl ester; 3-phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| CAS no. | 52645-53-1 |
| EINECS no. | 258-067-9 |
| Molecular formula | C21H20Cl2O3 |
APPLICATIONS
Permethrin is used in agricultural, textile, food and pharma industries. Some of the key applications where it is used are:
Insecticide
| to protect crops & to kill livestock parasites |
| on structures and buildings, including livestock housing and food-handling establishments. Permethrin can also be used in numerous residential sites, both indoor and outdoor and on pets |
| to prevent insect attack on woollen products |
| in aircraft disinfection |
Insect repellant
| as a personal protective measure, permethrin is applied to clothing. It is a cloth impregnant, notably in mosquito nets and field wear. |
| while permethrin may be marketed as an insect repellent, it doesn’t prevent insects from landing. Instead, it works by incapacitating or killing insects before they can bite. |
| in pet flea preventive collars or treatment (safe for use on dogs but not cats) |
| in timber treatment |
Medicinal
| available for topical use as a cream or lotion |
| used for the treatment and prevention in exposed individuals of head lice |
| used as a medication in the treatment of scabies in humans and animals |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description & Solubility | – | Yellow brownish coloured liquid which may solidify on standing or at lower temperature. Soluble in alcohol (96 % w/v) , Acetone, ether and hydrocarbons (Toluene) |
| Identification by IR | – | IR Spectrum exhibits maxima which are only at the same wave number as those in “Reference Spectrum of Permethrin- Working Standard” / CRS |
| Identification by HPLC | – | Retention time of Permethrin matches with retention time of standard in the assay test |
| Loss on Drying | % | NMT 0.2 |
| Sulphated Ash | % | NMT 0.2 |
| Assay by HPLC (on dried Basis) | % | 98.0 – 101.0 |
| Trans Isomer | % | 73.0 – 77.0 |
| Cis Isomer | % | 23.0 – 27.0 |
PACKAGING OPTIONS
25 Kg HDPE Drums
STORAGE
Store in a sheltered place away from sources of heat and moisture
Permethrin offered by ExSyn is WHO-GMP certified. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
4-Methoxypyridine, a molecule with ether function, is a reactive base. Its nitrogen atom is activated by the methoxy group. It renders the molecule active and thus 4-methoxypyrimidine participates in many chemical processes. Its uses are in intermediates, in synthesis of biologically active moieties, and in proteomic research.
Ammonium acetate is a crystalline white solid with a somewhat acetous odour. It is also called the spirit of Mindererus in its aqueous form or Azanium acetate. It is widely used in chemical analysis, in preserving foods, and in pharmaceuticals. It is often used to prepare buffer solutions as it is made up of a weak base and a weak acid combined together.
2,6-Lutidine is a liquid product and a semi-volatile compound naturally abundant in tobacco. Its main applications is as reagent in pharmaceuticals and as a solvent in chemical processes.
Dimethylthiocarbamoyl Chloride is an organosulfur compound, a yellow solid. It is often encountered as a yellow syrup. It is a key reagent in the synthesis of arylthiols via the Newman-Kwart rearrangement.
Tetrafluorobenzyl bromide (TFBB), by virtue of presence of 5 fluorine atoms, is a strong electrophile and hence readily combines with nucleophiles. This property results in its extensive usage in derivatization gas chromatography. Commercially, PFBB is applied to make the corresponding alcohol and chloride.
Ashwagandha also known as Withania somnifera, Winter cherry, or Indian Ginseng. Ashwagandha, one of the most valuable herbs in the Ayurvedic medical system dating back more than 3,000 years. Because of its vast area of application, ayurvedic physicians have used it extensively in curing people from their ailments.
4-(Dimethylamino)pyridine (DMAP) is an efficient and versatile acylation catalyst. Besides, it find uses in other chemical reactions as well as in production of APIs, agrochemicals, and intermediates.
L-Alpha glycerylphosphorylcholine (alpha-GPC or choline alfoscerate) is a choline-containing phospholipid. When ingested, alpha-GPC is metabolized into choline and glycerol-1-phosphate. Choline is a precursor of acetylcholine, a neurotransmitter involved in memory, attention, and skeletal muscle contraction.
3,3,3-Trifluoropropanol is a colorless liquid that is consumed in manufacture of value-added intermediates. This apart, the halogenated alcohol is also cited to have applications in other industry verticals. It also finds uses in proteomic research and in agrochemicals.