INTRODUCTION
PTSA or pTsOH or Tosylic acid (TsOH) is white solid organic compound, that is soluble in water, alcohols, and other polar organic solvents. The group is known as the tosyl group and is often abbreviated as Ts or Tos.
TsOH is about one million times stronger than benzoic acid. It is one of the few strong acids that is solid and hence conveniently weighed. It is available both in crystalline form as well as a solution and has a wide range of applications.
| Synonyms | 4-Methylbenzenesulfonic acid Tosic acid, Tosylic acid PTSA |
| CAS no. | 6192-52-5 (monohydrate) 104-15-4 (hydrous / solution) |
| EINECS no. | 203-180-0 |
| Molecular formula | C7H8SO3.H2O |
| Molecular weight | 190.22 |
| Structure |  |
APPLICATIONS
PTSA is widely used as a catalyst and as an intermediate in a variety of applications such as:
| A catalyst in the synthesis of pharmaceuticals, pesticides, polymerization stabilizer, paint intermediates, cross linking reactions and resin curing agent. It is also a commonly used acid catalyst in organic synthesis. |
| As an intermediate in fine chemicals, dyestuffs & pigments. |
| As a curing agent in thermosetting resin systems, varnishes, acrylic resins, etc. |
| As a hydrotropic coupling agent & a wetting agent in esterification / condensation / acetylation / polymerization / alkylation / hydrolysis / dehydration. |
| It is comparable in strength to mineral acids such as sulphuric acid but is especially suitable for organic reactions where an inorganic, mineral acid could cause charring, oxidation or an unwanted chemical reaction. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance* | – | White crystalline powder |
| Assay on Monohydrate basis | % | Min 98 |
| P-isomer content in the active Material by a) HPLC method b) Others | % – | Min 92 Balance |
| Free Sulphuric Acid | % | Max 0.3 |
| Iron Content | ppm | Max 10.0 |
| Total Moisture | % | Max 11.50 |
| Melting Point | °C | Min 99 |
| Solubility in water | – | 100% soluble, clear solution |
*Note: The international specification of PTSA is white to off white to pink, though the material supplied would be white. However, as the product is highly hygroscopic – due to heat, sunlight and moisture the color may change from white to off white or pinkish in the course of time.
SPECIFICATIONS of 65% solution
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Pale yellow to amber colored liquid |
| Assay (on Anhydrous basis) | % | Min 65.0 |
| Free Sulphuric acid | % | Max 1.0 |
| Specific gravity (at 25°C) | – | 1.22 ± 0.02 |
REACH status
PTSA offered by ExSyn is registered under EU REACH regulation.
STORAGE
The product is stored at ambient temperature.
ExSyn can offer PTSA grades as low as 0.1% free sulfuric acid, resulting in lower corrosion of user’s equipment and can also offer customized specifications if needed.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Acetonitrile (ACN) is a highly polar, volatile, colorless liquid with ethereal odor and is the simplest organic nitrile widely used as a solvent.
The nitrile group constitutes active part of the molecule. It participates in various reactions that lead to number of nitrogen containing organic molecules.
A complex salt of undetermined structure, composed of iron, ammonia and citric acid; there are two types of salts – brown and green – containing different amounts of iron
Trifluoroacetic acid (TFA), is widely used in organic synthesis as a solvent, catalyst and reagent thanks to its reactivity and stability under adverse conditions.
Niacinamide is a naturally occurring nutrient belonging to the pyridine carboxylic acid family. It is an important form of vitamin B3, an essential nutrient that supports many cellular processes and plays an important role in energy metabolism. Animal and refined grain-based products are fortified with Niacinamide.
Polyethylene [PE] wax is derived from ethylene through a process called polymerization. Manufacturers alter the polymerization process to get a product with desired qualities. An interesting feature of these waxes is the ability to be heated and cooled without extensive degradation.
Glycidol is a slightly viscous organic
compound that is characterized by presence of an epoxide in beta- position with respect to the alcoholic hydroxyl group. This renders instability to the compound resulting in a rapid decay. Hence the product is stored and transported under refrigerated conditions.
White Oils are manufactured from highly refined base oils and consist of saturated paraffinic and cycloparaffinic hydrocarbons. The refinement process ensures complete removal of aromatics, sulphur and nitrogen compounds resulting in products that are highly stable over time, besides being hydrophobic, colourless, odourless and tasteless.
A versatile dye used for medicinal applications, now a potential, alternative treatment in SARS-CoV-2 infection complications.
The aromatic is a liquid with a pleasant odor. The active methoxy group attached to a benzene ring renders a high amount of reactivity to the molecule. Worldwide, anisole is commercially produced by methylation of phenol.