INTRODUCTION
PTSA or pTsOH or Tosylic acid (TsOH) is white solid organic compound, that is soluble in water, alcohols, and other polar organic solvents. The group is known as the tosyl group and is often abbreviated as Ts or Tos.
TsOH is about one million times stronger than benzoic acid. It is one of the few strong acids that is solid and hence conveniently weighed. It is available both in crystalline form as well as a solution and has a wide range of applications.
| Synonyms | 4-Methylbenzenesulfonic acid Tosic acid, Tosylic acid PTSA |
| CAS no. | 6192-52-5 (monohydrate) 104-15-4 (hydrous / solution) |
| EINECS no. | 203-180-0 |
| Molecular formula | C7H8SO3.H2O |
| Molecular weight | 190.22 |
| Structure |  |
APPLICATIONS
PTSA is widely used as a catalyst and as an intermediate in a variety of applications such as:
| A catalyst in the synthesis of pharmaceuticals, pesticides, polymerization stabilizer, paint intermediates, cross linking reactions and resin curing agent. It is also a commonly used acid catalyst in organic synthesis. |
| As an intermediate in fine chemicals, dyestuffs & pigments. |
| As a curing agent in thermosetting resin systems, varnishes, acrylic resins, etc. |
| As a hydrotropic coupling agent & a wetting agent in esterification / condensation / acetylation / polymerization / alkylation / hydrolysis / dehydration. |
| It is comparable in strength to mineral acids such as sulphuric acid but is especially suitable for organic reactions where an inorganic, mineral acid could cause charring, oxidation or an unwanted chemical reaction. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance* | – | White crystalline powder |
| Assay on Monohydrate basis | % | Min 98 |
| P-isomer content in the active Material by a) HPLC method b) Others | % – | Min 92 Balance |
| Free Sulphuric Acid | % | Max 0.3 |
| Iron Content | ppm | Max 10.0 |
| Total Moisture | % | Max 11.50 |
| Melting Point | °C | Min 99 |
| Solubility in water | – | 100% soluble, clear solution |
*Note: The international specification of PTSA is white to off white to pink, though the material supplied would be white. However, as the product is highly hygroscopic – due to heat, sunlight and moisture the color may change from white to off white or pinkish in the course of time.
SPECIFICATIONS of 65% solution
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Pale yellow to amber colored liquid |
| Assay (on Anhydrous basis) | % | Min 65.0 |
| Free Sulphuric acid | % | Max 1.0 |
| Specific gravity (at 25°C) | – | 1.22 ± 0.02 |
REACH status
PTSA offered by ExSyn is registered under EU REACH regulation.
STORAGE
The product is stored at ambient temperature.
ExSyn can offer PTSA grades as low as 0.1% free sulfuric acid, resulting in lower corrosion of user’s equipment and can also offer customized specifications if needed.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Linoleic acid is a polyunsaturated omega-6 fatty acid. It is a colorless liquid that is virtually insoluble in water but soluble in many organic solvents. It typically occurs in nature as a triglyceride (ester of glycerin) rather than as a free fatty acid.
Ethyl Linoleate belongs to the chemical class of fatty acids, which are organic compounds with one or more long hydrocarbon chains. These molecules are characterized by having two carbons atoms with a double bond between them.
2-Picolinic acid, an organic compound, is a derivative of pyridine with a carboxylic acid substituent at the 2-position. It is a white solid that is soluble in water.
2-Phenylethylamine is a water-soluble amine with a fishy odor. It is often referred to simply as “phenethylamine”, but that can also be interpreted as 1-phenylethylamine.
4-Amino-1,2,4-triazole is an organic solid belonging to the heterocyclic category of compounds. By virtue of presence of 3 nitrogen atoms, the molecule is biologically active and thus acts as antimicrobial and antifungal agent.
4’-Cyanoacetophenone is an organic solid. It belongs to cyclic nitriles category. The presence of cyano group makes the compound reactive to form various intermediates and a few APIs. In organics syntheses, it also used as a catalyst.
3- Bromothianisole is a brominated aromatic compound with an active methyl thio group for oxidation. It has many applications in pharmaceutical and biotech industries as an intermediate for the synthesis of various organic compounds
Dichloroacetyl chloride, acronymed DCAC, is an organic solvent that belongs to the category of acid chlorides. Its uses include manufacture of APIs, agrochemicals, and a series of intermediates. It is also applied in synthesis of biologically active compounds.
1-(Difluoromethyl)-4-nitro-1H-pyrazole is a difluoromethyl aromatic compound with an active nitro group for reduction. It is used as an organic synthesis key starting material and intermediate in APIs.