INTRODUCTION
PTSA or pTsOH or Tosylic acid (TsOH) is white solid organic compound, that is soluble in water, alcohols, and other polar organic solvents. The group is known as the tosyl group and is often abbreviated as Ts or Tos.
TsOH is about one million times stronger than benzoic acid. It is one of the few strong acids that is solid and hence conveniently weighed. It is available both in crystalline form as well as a solution and has a wide range of applications.
| Synonyms | 4-Methylbenzenesulfonic acid Tosic acid, Tosylic acid PTSA |
| CAS no. | 6192-52-5 (monohydrate) 104-15-4 (hydrous / solution) |
| EINECS no. | 203-180-0 |
| Molecular formula | C7H8SO3.H2O |
| Molecular weight | 190.22 |
| Structure |  |
APPLICATIONS
PTSA is widely used as a catalyst and as an intermediate in a variety of applications such as:
| A catalyst in the synthesis of pharmaceuticals, pesticides, polymerization stabilizer, paint intermediates, cross linking reactions and resin curing agent. It is also a commonly used acid catalyst in organic synthesis. |
| As an intermediate in fine chemicals, dyestuffs & pigments. |
| As a curing agent in thermosetting resin systems, varnishes, acrylic resins, etc. |
| As a hydrotropic coupling agent & a wetting agent in esterification / condensation / acetylation / polymerization / alkylation / hydrolysis / dehydration. |
| It is comparable in strength to mineral acids such as sulphuric acid but is especially suitable for organic reactions where an inorganic, mineral acid could cause charring, oxidation or an unwanted chemical reaction. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance* | – | White crystalline powder |
| Assay on Monohydrate basis | % | Min 98 |
| P-isomer content in the active Material by a) HPLC method b) Others | % – | Min 92 Balance |
| Free Sulphuric Acid | % | Max 0.3 |
| Iron Content | ppm | Max 10.0 |
| Total Moisture | % | Max 11.50 |
| Melting Point | °C | Min 99 |
| Solubility in water | – | 100% soluble, clear solution |
*Note: The international specification of PTSA is white to off white to pink, though the material supplied would be white. However, as the product is highly hygroscopic – due to heat, sunlight and moisture the color may change from white to off white or pinkish in the course of time.
SPECIFICATIONS of 65% solution
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Pale yellow to amber colored liquid |
| Assay (on Anhydrous basis) | % | Min 65.0 |
| Free Sulphuric acid | % | Max 1.0 |
| Specific gravity (at 25°C) | – | 1.22 ± 0.02 |
REACH status
PTSA offered by ExSyn is registered under EU REACH regulation.
STORAGE
The product is stored at ambient temperature.
ExSyn can offer PTSA grades as low as 0.1% free sulfuric acid, resulting in lower corrosion of user’s equipment and can also offer customized specifications if needed.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Pyrophosphoryl chloride is colourless to pale yellow liquid, reasonably easy to handle. It reacts violently with water & miscible with most organic solvents.
It is used in pharmaceutical and other organic synthesis, as laser materials and electronic components.
Benzilic acid ethyl ester is an oil organic liquid. Its reactivity is attributed to the presence of the hydroxyl group at alpha-position to the carboxylic acid group and hence it participates in various reactions leading to value-added intermediates and APIs.
Bromobenzene, an aryl halide, is a clear, colorless liquid with a pleasant odor. It is soluble in methanol and diethyl ether, and very slightly soluble in cold water.
Dibutyltin laurate is an organotin compound with oily appearance. The lauric acid ester is used in various industrial applications as catalyst.
Pyridine hydrobromide is a white to off-white hygroscopic crystalline solid with melting point/freezing point of 216 °C to 219 °C. It is miscible in water. It used in many chemical synthesis studies.
Chrysanthemic acid is a cyclic organic compound. The product occurs naturally in its ester form in pyrethrum flowers. It is also found as metabolite of pyrenthrins. The acid carries a sweet odor thereby enabling its uses in flavors and is used to synthesize agrochemicals as well.
Propionic Anhydride is a colorless liquid having a pungent odor and high boiling point. It is miscible with most organic solvents. It is soluble in both water and alcohol. It is a widely used reagent in organic synthesis as well as for producing specialty derivatives of cellulose.
2-Cyclohexene-1-one is an organic intermediate used in synthesis of pharmaceuticals, agrochemicals, and fragrances. It is a ketone, or more precisely, an enone.
It is an alkaloid used in the symptomatic relief of pain in attacks of gouty arthritis, pseudogout, sarcodial arthritis, calcific tendinitis and to treat the inflammatory symptoms of Familial Mediterranean Fever.
It appears as odourless or nearly odourless pale yellow needles or powder that darkens on exposure to light.