INTRODUCTION
PTSA or pTsOH or Tosylic acid (TsOH) is white solid organic compound, that is soluble in water, alcohols, and other polar organic solvents. The group is known as the tosyl group and is often abbreviated as Ts or Tos.
TsOH is about one million times stronger than benzoic acid. It is one of the few strong acids that is solid and hence conveniently weighed. It is available both in crystalline form as well as a solution and has a wide range of applications.
Synonyms | 4-Methylbenzenesulfonic acid Tosic acid, Tosylic acid PTSA |
CAS no. | 6192-52-5 (monohydrate) 104-15-4 (hydrous / solution) |
EINECS no. | 203-180-0 |
Molecular formula | C7H8SO3.H2O |
Molecular weight | 190.22 |
Structure | ![]() |
APPLICATIONS
PTSA is widely used as a catalyst and as an intermediate in a variety of applications such as:
A catalyst in the synthesis of pharmaceuticals, pesticides, polymerization stabilizer, paint intermediates, cross linking reactions and resin curing agent. It is also a commonly used acid catalyst in organic synthesis. |
As an intermediate in fine chemicals, dyestuffs & pigments. |
As a curing agent in thermosetting resin systems, varnishes, acrylic resins, etc. |
As a hydrotropic coupling agent & a wetting agent in esterification / condensation / acetylation / polymerization / alkylation / hydrolysis / dehydration. |
It is comparable in strength to mineral acids such as sulphuric acid but is especially suitable for organic reactions where an inorganic, mineral acid could cause charring, oxidation or an unwanted chemical reaction. |
SPECIFICATIONS
Test | Unit | Specification |
---|---|---|
Appearance* | – | White crystalline powder |
Assay on Monohydrate basis | % | Min 98 |
P-isomer content in the active Material by a) HPLC method b) Others | % – | Min 92 Balance |
Free Sulphuric Acid | % | Max 0.3 |
Iron Content | ppm | Max 10.0 |
Total Moisture | % | Max 11.50 |
Melting Point | °C | Min 99 |
Solubility in water | – | 100% soluble, clear solution |
*Note: The international specification of PTSA is white to off white to pink, though the material supplied would be white. However, as the product is highly hygroscopic – due to heat, sunlight and moisture the color may change from white to off white or pinkish in the course of time.
SPECIFICATIONS of 65% solution
Test | Unit | Specification |
---|---|---|
Appearance | – | Pale yellow to amber colored liquid |
Assay (on Anhydrous basis) | % | Min 65.0 |
Free Sulphuric acid | % | Max 1.0 |
Specific gravity (at 25°C) | – | 1.22 ± 0.02 |
REACH status
PTSA offered by ExSyn is registered under EU REACH regulation.
STORAGE
The product is stored at ambient temperature.
ExSyn can offer PTSA grades as low as 0.1% free sulfuric acid, resulting in lower corrosion of user’s equipment and can also offer customized specifications if needed.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Colchicine is a naturally occurring alkaloid obtained primarily from the autumn crocus (Colchicum autumnale) and related species. It has been used in medicine for centuries, especially for the treatment of gout and Familial Mediterranean Fever. In modern medicine, Colchicine is valued also in conditions like pericarditis, Behçet’s disease, and certain dermatological and cardiac disorders.
1-Butylimidazole is a versatile organic heterocyclic compound belonging to the imidazole family, where a butyl group (–CH₂–CH₂–CH₂–CH₃) is attached to the nitrogen atom at the 1-position of the imidazole ring. Its applications span organic synthesis, materials science, and bioactive compound development due to its tunable physicochemical properties and structural versatility.
Atropine sulfate monohydrate is a chemical compound, specifically a salt of atropine and sulfuric acid, with one water molecule (monohydrate) attached. It is commonly used as a medication and in research due to its anticholinergic properties, meaning it blocks the effects of acetylcholine at muscarinic receptors.
4-Aminobenzoic acid, commonly abbreviated as PABA, is an aromatic amine and carboxylic acid compound. It consists of a benzene ring substituted with an amino group (–NH₂) in the para position to a carboxylic acid group (–COOH).
2-Amino-5-Nitrophenol (5-NAP) is an organic compound with the molecular formula C₆H₆N₂O₃. It is a substituted phenol with both an amino group (-NH₂) and a nitro group (-NO₂) attached to a benzene ring, along with a hydroxyl group (-OH).
Pongamol is a naturally occurring flavonoid primarily extracted from the seeds and leaves of the Pongamia pinnata tree (also known as Karanja tree), native to South and Southeast Asia. It is a cream-colored compound that belongs to the flavonoid family and is known for its antioxidant, anti-inflammatory, antimicrobial, and pesticidal properties. It is one of the key bioactive constituents of Pongamia oil.
Biobased Ethyl Acetate is an environmentally friendly solvent made from renewable sources like bioethanol extracted from sugarcane, corn, and other forms of biomass. Unlike traditional ethyl acetate, which is typically derived from fossil fuels, this green alternative shares the same chemical structure (C₄H₈O₂) and functional performance—offering comparable versatility with a significantly lower environmental footprint.
Palmitoyl chloride is a long-chain fatty acid derivative. It is the acid chloride form of palmitic acid; a saturated fatty acid commonly found in palm oil and other natural fats. It appears as a colorless to pale yellow liquid with a sharp odour and is highly reactive, especially toward water, alcohols, and amines.
Fungal Lycopene is an acyclic carotene belonging to a large group of naturally-occurring pigments known as carotenoids. It contains at least 90% of all-trans-lycopene and minor quantities of 13-cis-lycopene and β- and γ-carotene. It is used as an intermediate in the biosynthetic pathway of β-carotene. Its role in the pharmaceutical and food industries stems from its demonstrated health benefits—such as anticancer and cardiovascular protection—alongside its widespread use as a natural food colorant.