N.N’-Dicyclohexylcarbodiimide, acronymed as DCCD by chemists, is a versatile reagent in organic syntheses. Its reactivity is due to the presence of carbodiimide group in its structure. The compound undergoes various reactions to form APIs and intermediates.
It is manufactured from N.N’-dicyclohexylurea either by using phosphorous oxychloride or phosphorous pentoxide.
|APIs: The diimide is used in the synthesis of APIs such as
|Benexate HCl, an anti-ulcer drug
|Angiotensin II, an anti-hypertensive drug and a peptide hormone
|Docetaxel, an anti-cancer drug, also used in treatment of chronic heart failures
|Intermediates: DCCD is used as a reagent in the synthesis of intermediates like
|As dehydrating agent
|As coupling agent in APIs and peptides
|In synthesis of acid anhydrides, aldehydes, ketones, and isocyanates
|In inversion and esterification of secondary alcohols
|Colorless to pale yellow liquid to semi-solid
|Identification by GC
|The retention time of the major peak in the chromatogram of the sample solution corresponds to that in the chromatogram of the standard solution
|Soluble in methanol and sparingly soluble in acetone
|Purity by GC
Stored at ambient temperature.
35 kg UN approved Jerrycan.
Not registered yet.
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