INTRODUCTION
N-Acetyl-L-aspartic acid, abbreviated as NAA, is second most abundant molecule in nervous systems after amino acid glutamate. It is synthesized in brain from aspartic acid and acetyl co-enzyme A. It also acts as nutrient.
Manufacture
In a biological process, NAA is produced from rat brain acetone. Commercially, it is manufactured by acetylation of L-aspartic acid bis(trimethylsilyl)ester using acetyl chloride.
| Synonyms | N-Acetyl aspartate NAA |
| CAS no. | 997-55-7 |
| EINECS no. | 213-643-9 |
| Molecular formula | C6H9NO5 |
| Molecular weight | 175.14 |
| Structure |  |
Applications in Synthesis
| The chiral acid is used to synthesize: |
|---|
| Its anhydride |
| Homoserine gamma-lactones |
Other Applications
| As reagent in selective reductions of cyclic ketones |
| In acid-catalyzed cyclization reactions |
| In peptide synthesis |
| As a nutraceutical supplement in capsule, tablet, and liquid dosage form |
| As antioxidant |
| As human and rat metabolites |
| Isotopic form used in studies for metabolic alteration associated with schizophrenia |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | White powder |
| Specific rotation (C = 1, HAc) | Degree | 50.0 – 54.0 |
| Water | % | Max 0.5 |
| Assay | % | Min 98.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
25 kg Fibre drum.
REACH Status
Not Registered yet.
ExSyn offers N-acetyl-L-aspartic acid on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Benzene-d6 is a deuterated form of benzene, where hydrogen atoms are replaced by deuterium, making it ideal for use as a solvent in NMR spectroscopy. It is widely employed in chemical, pharmaceutical, and environmental research for isotopic labeling and reaction mechanism studies.
Pyridinium tribromide, an organic solid from the category of heterocyclic halides, is a highly efficient and selective bromination agent in organic syntheses. It is also used in production of APIs and intermediates.
Pyrophosphoryl Tetrachloride is a colorless fuming corrosive liquid .It consists of a pyrophosphate (a molecule with a P-O-P bond) group, where one phosphorus atom is bonded to four chlorine atoms and the other is bonded to three chlorine atoms.
It is a reactive chemical compound and should be handled with care. Commonly used in the synthesis of other phosphorus-containing compounds and as a chlorinating agent in organic chemistry
Trifluoroacetic acid (TFA) is widely used in organic synthesis as a solvent, catalyst, and reagent, owing to its reactivity and stability under adverse conditions. It is considered as one of the most economical fluorinated building blocks.
Acryloyl chloride is an organic liquid from the class of acid chlorides. It is a toxic and lachrymatic chemical that has a variety of applications in APIs, intermediates and polymers.
Triton X-100 is a widely used non-ionic surfactant and emulsifier that effectively solubilizes powders and proteins. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.
Chlorocresol, or 4-chloro-3-methylphenol, also known as p-chloro-m-cresol, is efficacious against various bacteria, yeast and fungi. It is a potent disinfectant and antiseptic and acts as preservative in cosmetics, medicinal, and personal care products for both humans and animals.
INTRODUCTION 2-Mercaptopyridine, a sulfur-containing heterocyclic compound, is a derivative of pyridine with a thiol functional group. This compound has garnered interest in various fields, including organic synthesis, medicinal chemistry, and materials science. MANUFACTURE It is synthesized by reacting 2-chloropyridine with thiourea in ethanol and aqueous ammonia. The mixture is heated to reflux, facilitating nucleophilic substitution […]
INTRODUCTION Glycidol is a viscous organic compound that belongs to the class of beta-oxyalcohols. Its reactivity is attributed to the epoxy moiety at beta position. The alcohol finds applications majorly in APIs, glycidyl esters and ethers, and in alkanolamines. Manufacture It is manufactured from 2-Chloro-1,3-propanediol in a catalyzed ring closure process. The unreacted reactant is […]