INTRODUCTION

N-Acetyl-L-aspartic acid, abbreviated as NAA, is second most abundant molecule in nervous systems after amino acid glutamate. It is synthesized in brain from aspartic acid and acetyl co-enzyme A. It also acts as nutrient.

Manufacture
In a biological process, NAA is produced from rat brain acetone. Commercially, it is manufactured by acetylation of L-aspartic acid bis(trimethylsilyl)ester using acetyl chloride.

SynonymsN-Acetyl aspartate
NAA
CAS no.997-55-7
EINECS no.213-643-9
Molecular formulaC6H9NO5
Molecular weight175.14
Structure

Applications in Synthesis

The chiral acid is used to synthesize:
Its anhydride
Homoserine gamma-lactones

Other Applications

As reagent in selective reductions of cyclic ketones
In acid-catalyzed cyclization reactions
In peptide synthesis
As a nutraceutical supplement in capsule, tablet, and liquid dosage form
As antioxidant
As human and rat metabolites
Isotopic form used in studies for metabolic alteration associated with schizophrenia

SPECIFICATIONS

TestUnitSpecification
AppearanceWhite powder
Specific rotation (C = 1, HAc)Degree50.0 – 54.0
Water%Max 0.5
Assay%Min 98.0

STORAGE
The product is stored at ambient temperature.

PACKING
25 kg Fibre drum.

REACH Status
Not Registered yet.

ExSyn offers N-acetyl-L-aspartic acid on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

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