INTRODUCTION
Methyl magnesium chloride is the simplest of Grignard’s reagents. The neat molecule is sensitive to air and moisture. Therefore, it is offered as solution in THF with variable molarity values. At low temperature, it may crystallize out as THF complex and regain solution form at ambient temperature.
Manufacture
The product is manufactured by reaction of chloromethane with magnesium in anhydrous diethyl ether. The synthesis generally requires presence of an initiator.
| Synonyms | Methyl (chloro) magnesium Magnesium carbanide chloride |
| CAS no. | 676-58-4 |
| EINECS no. | 211-629-7 |
| Molecular formula | CH3MgCl |
| Molecular weight | 74.79 |
| Structure |  |
Applications
| APIs |
|---|
| Ganaxolone, a synthetic neuroactive steroid |
| Medetomidine, a sedative veterinary |
| Chlorphenoxamine, an anticholinergic |
| Clemastine, an antihistamine |
| Intermediates |
|---|
| Dimethyl magnesium |
| Tetramethyl lead |
| Tetramethyl tin |
| Bis(cyclopentadienyl)dimethyl titanium |
| Styrallyl alcohol |
| 2,6-Dimethyl-2-heptanol |
| Dimethyl phenethyl carbinol |
| Flavors & Fragrances |
|---|
| Hydroxycitronellal, an odorant with floral fragrance |
| Propenyl guaethol, flavor ingredient with vanilla odor |
| Others |
|---|
| Selective methylation agent for aldehydes, ketones, and carbonyls in organic syntheses |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Dark brown to grey coloured liquid |
| Molarity | M | 2.90 – 3.30 |
| Sedimentation | % | Max 2.0 |
STORAGE
Stored at ambient temperature under nitrogen blanket
PACKING
190 kg UN approved HDPE drums
REACH Status
Not registered yet
ExSyn offers methyl magnesium chloride on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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