INTRODUCTION

Indole-3-carbinol is a colorless powder with a characteristic odor.

The product finds uses in various fields by virtue of the indole ring, which is active and mainly imparts medicinal properties to the molecule. It is also an important dietary supplement.

Manufacture
Biologically, it is produced by enzyme-catalysed hydrolysis of glucosinolate, abundantly found in cabbage, cauliflower, and other vegetables of Bressica family.
Synthetically and commercially, it is product of indole-3-acetic acid reduction.

SynonymsIndole-3-methanol
CAS no.700-06-1
EINECS no.211-836-2
Molecular formulaC9H9NO
Molecular weight147.17
Structure

Medicinal Uses
Indiole-3-carbinol is cited to have medicinal properties and is subject of many clinical trials. It is applied in medicines to:

prevent breast cancer
cure obesity
lower risk of prostate cancer recurrence

Nutritional Uses

As an antioxidant
Dietary supplement

Value-added Intermediates
Indole-3-carbinol is used as a KRM to make various intermediates for pharmaceutical applications, such as:

Indole-3-carboxylic acid
Indole-3-carboxaldehyde
Indolo[3,2b]carbazole
3,3’-Diindolylmethane

SPECIFICATIONS

TestUnitSpecification
AppearanceOff-white to red powder
IdentificationShould give positive reaction
Melting range°C97-100
Loss on drying%Max 2.0
Residue on ignition%Max 0.1
Residual solventsNot detected
Assay by HPLC%Min 99.0
Total heavy metalsppmMax 10.0
LeadppmMax 0.5
ArsenicppmMax 0.5
MercuryppmMax 0.1
CadmiumppmMax 0.5
Particle size
40 mesh%100
80 mesh%80
120 mesh%60
Microbial Test
Total plate countcfu/gMax 1000
Yeast and moldcfu/gMax 100
SalmonellaShould be absent
E ColiShould be absent
StaphylococcusShould be absent
PseudomonasShould be absent

CERTIFICATION
The product is offered from NSF-GMP facility supported by a DMF for Nutraceutical application.

STORAGE
Recommended storage temperature is 2° to 8°C

PACKING
10 kg bag in HDPE Drum

ExSyn offers indole-3-carbinol on commercial scale and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.

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