INTRODUCTION

Diphenylphosphoryl azide, known as DPPA, is a versatile azidation agent in organic chemistry. Its applications include preparation of organo azides, production of intermediates, synthesis of lactams, and many others.

Manufacture
It is manufactured by acid catalysis reaction between phosphoryl chloride and aniline.

SynonymDPPA
Phosphoric acid diphenyl ester azide
CAS no.26386-88-9
EINECS no.247-644-0
Molecular formulaC12H10N3PO5
Molecular weight275.20
Structure

Applications

Agrochemicals
Carfentrazone Ethyl (herbicide)
Intermediates
N-(Diphenoxyphosphoryldiazenyl)aniline
(Trimethylsilyl)diazomethane
Bis(4-nitrohenyl)phosphorazidate
2-Thionyl isocyanate
Others
As hydroazidation catalyst for making organo azides by Mitsunobu reaction
As reagent in synthesis of oligosaccharides and in Curtis Rearrangement reaction
In aziridation of olefins
In preparation of aldose reductase inhibitor
As activation agent in macrocytic lactam preparation
As RM in synthesis of carbamates from carboxylic acids
As KRM in racemization-free peptide synthesis and phosphoramidates

SPECIFICATIONS

TestUnitSpecification
AppearanceColourless to slight yellow liquid
Moisture%Max 0.50
Purity by GC%Min 97.00

STORAGE
Stored at ambient temperature.

PACKING
50 kg UN approved HDPE drum.

REACH Status
Not registered yet.

ExSyn offers DPPA on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

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