INTRODUCTION

Benzyl nicotinate is a benzyl ester resulting from the condensation of the carboxy group of nicotinic acid with benzyl alcohol.

It has a role as a vasodilator agent and is also generally used in cosmetics and drugs. It is an active substance from the group of rubefacients that stimulates blood circulation. Also used in veterinary as well as in human medicines.

SynonymsNicotinic acid benzyl ester
Benzyl pyridine-3-carboxylate
CAS no.94-44-0
EINECS no.202-332-3
Molecular formulaC13H11NO2
Molecular weight213.23
Structure

Applications

Used in the treatment of nutritional deficiencies
Used to reduce the plasma cholesterol
In combination with heparin, used in the treatment of inflammation of vein (thrombophlebitis), pain in dilated veins area, pains and cramps in the leg muscles, disturbances of lymph circulation, traffic and sports related injuries, postoperative and posttraumatic scars, non-joint rheumatism or soft tissue rheumatism
Used as skin-conditioning  and anti-static agent in creams, baths and emulsions
Used for the synthesis of benzyl palladium complexes to be used as catalysts for the substitution of olefins with benzylic groups

SPECIFICATIONS

TestUnitSpecification
DescriptionClear, yellowish to brownish yellow or slightly reddish oily liquid with characteristic odor
SolubilityMiscible with acetone, dichloromethane, ethanol (96%) and in Ether
Identification (by IR)Test as per DAB 99 specs should be positive
Appearance of solutionTest as per DAB 99 specs should comply
Acidic substancesNMT 1 ml of 0.05 M NaOH solution is consumed
Refractive Index1.569 – 1.570
Halogen CompoundsppmNMT 500
Sulphated Ash% w/wNMT 0.1
Specific Gravity at 25°Cg/ml1.150 – 1.170
Assay (Perchloric acid titration)%NLT 98.0 & NMT 101.0
Related Substances (by GC)
Single impurities%NMT 0.5
Total impurities%NMT 1.0

STORAGE
Store in a cool & dry location and in well-ventilated area.

PACKING
20 kg HDPE Carboy.

Benzyl Nicotinate offered by ExSyn is available on commercial scale. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.

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