4-(Dimethylamino)pyridine (DMAP) is an efficient and versatile acylation catalyst. Besides, it find uses in other chemical reactions as well as in production of APIs, agrochemicals, and intermediates.
The product is commercially manufactured by methylation of 4-pyridinamine. Alternatively, it is produced by ammonolysis of 4-hydroxypyridine followed by the methylation.
Applications in APIs
|DMAP is consumed in production of APIs such as:|
|Abacavir (nucleoside reverse transcriptase inhibitor)|
|Ivacaftor (Cystic Fibrosis Treatment)|
|Paclitaxel (anti-Caner, antineoplastic)|
Applications in Agrochemicals
|The dimethylated pyridine is used to produce agrochemicals:|
Applications in Intermediates
|DMAP is also a KRM for the synthesis of the following intermediates:|
It also acts as a catalyst in some alkylation, etherification, and esterification reactions.
|Appearance||–||White to off-white crystalline solid|
|Identifications by GC||–||Retention time of the major peak matches with that of the reference standard|
|Moisture by KF||% w/w||Max 0.1|
|Purity by GC||%||Min 99.00|
|Assay by chemical method||%||Min 99.00|
The product is stored at ambient temperature.
25 kg fibre drum.
DMAP offered by ExSyn is registered under EU REACH regulations.
ExSyn offers DMAP on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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