INTRODUCTION

2-Cyclohexene-1-one is an organic intermediate used in synthesis of pharmaceuticals, agrochemicals, and fragrances. It is a ketone, or more precisely, an enone. It undergoes nucleophilic conjugate addition with organocopper reagents, Michael reactions and Robinson annulations.

Manufacture
The product is commercially manufactured by Birch reduction of phenol or anisole, alternatively by catalytic oxidation of cyclohexene.

SynonymsCyclohexenone
Cyclohex-2-enone
CAS no.930-68-7
EINECS no.212-223-5
Molecular formulaC6H8O
Molecular weight96.13
Structure

Applications in Pharma

Cyclohexenone is a key raw material in the production of:
Carprofen, a nonsteroidal anti-inflammatory drug

Applications in Agrochemicals

It is also used to synthesize the herbicides:
Clethodim
Tralkoxydim

Applications in Intermediates

Following intermediates can be synthesized from cyclohexenone:
3-Methylcyclohexanone
2-(Hydroxymethyl)cyclohex-2-en-1-one

Other Applications

As fragrance ingredient with roasted savory green odor
In biological studies for H-tunneling in multiple hydride transfers of catalytic cycle of the enzyme – morphinone reductase

SPECIFICATIONS

TestUnitSpecification
AppearanceClear, colorless or slightly yellowish liquid
Identification by GCPeak in the sample chromatogram to match with that in standard chromatogram
Water by KFw/vMax 0.5
Density at 20°C0.987 – 0.997
Purity by GC%Min 98.0

STORAGE
The product is stored at ambient temperature.

PACKING
25 kg UN-approved carboy.

REACH Status
Not registered yet.

ExSyn offers 2-cyclohexene-1-one on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In Focus: Cetylpyridinium chloride monohydrate
Products in focus · 28/02/2024

Cetylpyridinium chloride is the chloride salt form of cetylpyridinium, a quaternary ammonium with broad-spectrum antimicrobial activity. Upon topical administration, cetylpyridinium chloride is positively charged and reacts with the negatively charged microbial cell surfaces, thereby destroying the integrity of the cell membrane.

READ MORE
In Focus:N2-isobutyryl-2′-OMe-guanosine
Products in focus · 20/02/2024

N2-Isobutyryl-2′-O-methyl-guanosine (IBG) is a modified nucleoside that has gained significant attention in recent years due to its potential therapeutic and industrial applications. IBG is a derivative of guanosine, a nucleoside that is a building block of RNA and DNA.

READ MORE
In Focus: Trimethylaluminium, 2M in Toluene
Products in focus · 13/02/2024

Trimethylaluminium belongs to class of organometallics. It is a highly reactive chemical and its solution in toluene is normally used to facilitate workability. Its general applications are in cross coupling and carboalumination reactions.

READ MORE
In Focus : Octenidine Dihydrochloride
Products in focus · 06/02/2024

Octenidine dihydrochloride is a cationic surfactant, with a gemini-surfactant structure. Since 1987, it has been used primarily in Europe as an antiseptic prior to medical procedures, including on neonates. It is safe to handle and chemically stable.

READ MORE
In Focus : Allyl Glycidyl Ether
Products in focus · 30/01/2024

Allyl Glycidyl Ether (AGE) is a multifunctional organic intermediate made from epichlorohydrin and allyl chloride and is featured by high functionality and low chlorine content. Since it has an epoxy group and an allyl group, AGE reacts with a wide range of compounds.

READ MORE
In Focus : L-Fucose
Products in focus · 23/01/2024

L-Fucose is a colourless solid that belongs to class of deoxy sugars and is considered as one of the essential sugars for smooth functioning of the body. It occurs naturally in brown algal polysaccharide fucoidan and gums.

READ MORE
In Focus : Liposomal Iron
Products in focus · 16/01/2024

Liposomal iron involves encapsulating iron molecules within lipid bilayers. This encapsulation protects the iron from interactions with other compounds, enhance its stability, improve its bioavailability and low incidence of side effects.

READ MORE
In Focus – Polyethylene Glycol (PEG) – Pharma Grade
Products in focus · 09/01/2024

Polyethylene glycols (PEG), also known as macrogols, are liquid or solid polymers of the general formula H(OCH2CH2)n OH, where n is greater or equal to four.

READ MORE
In Focus : Arachidonic Acid
Products in focus · 19/12/2023

Arachidonic acid is an omega-6 fatty acid. The compound is abundant in liver, brain, and depot fats of animals. It is also found in chicken, egg, fish, and human mother milk.

READ MORE