INTRODUCTION

2-Cyclohexene-1-one is an organic intermediate used in synthesis of pharmaceuticals, agrochemicals, and fragrances. It is a ketone, or more precisely, an enone. It undergoes nucleophilic conjugate addition with organocopper reagents, Michael reactions and Robinson annulations.

Manufacture
The product is commercially manufactured by Birch reduction of phenol or anisole, alternatively by catalytic oxidation of cyclohexene.

SynonymsCyclohexenone
Cyclohex-2-enone
CAS no.930-68-7
EINECS no.212-223-5
Molecular formulaC6H8O
Molecular weight96.13
Structure

Applications in Pharma

Cyclohexenone is a key raw material in the production of:
Carprofen, a nonsteroidal anti-inflammatory drug

Applications in Agrochemicals

It is also used to synthesize the herbicides:
Clethodim
Tralkoxydim

Applications in Intermediates

Following intermediates can be synthesized from cyclohexenone:
3-Methylcyclohexanone
2-(Hydroxymethyl)cyclohex-2-en-1-one

Other Applications

As fragrance ingredient with roasted savory green odor
In biological studies for H-tunneling in multiple hydride transfers of catalytic cycle of the enzyme – morphinone reductase

SPECIFICATIONS

TestUnitSpecification
AppearanceClear, colorless or slightly yellowish liquid
Identification by GCPeak in the sample chromatogram to match with that in standard chromatogram
Water by KFw/vMax 0.5
Density at 20°C0.987 – 0.997
Purity by GC%Min 98.0

STORAGE
The product is stored at ambient temperature.

PACKING
25 kg UN-approved carboy.

REACH Status
Not registered yet.

ExSyn offers 2-cyclohexene-1-one on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Pyrophosphoryl Chloride
Products in focus · 29/11/2022

Pyrophosphoryl chloride is colourless to pale yellow liquid, reasonably easy to handle. It reacts violently with water & miscible with most organic solvents.
It is used in pharmaceutical and other organic synthesis, as laser materials and electronic components.

READ MORE
In focus: Benzilic Acid Ethyl Ester
Products in focus · 22/11/2022

Benzilic acid ethyl ester is an oil organic liquid. Its reactivity is attributed to the presence of the hydroxyl group at alpha-position to the carboxylic acid group and hence it participates in various reactions leading to value-added intermediates and APIs.

READ MORE
In focus: Bromobenzene
Products in focus · 15/11/2022

Bromobenzene, an aryl halide, is a clear, colorless liquid with a pleasant odor. It is soluble in methanol and diethyl ether, and very slightly soluble in cold water.

READ MORE
In focus: Dibutyltin Dilaurate
Products in focus · 08/11/2022

Dibutyltin laurate is an organotin compound with oily appearance. The lauric acid ester is used in various industrial applications as catalyst.

READ MORE
In focus: Pyridine Hydrobromide
Products in focus · 01/11/2022

Pyridine hydrobromide is a white to off-white hygroscopic crystalline solid with melting point/freezing point of 216 °C to 219 °C. It is miscible in water. It used in many chemical synthesis studies.

READ MORE
In focus: Chrysanthemic acid
Products in focus · 25/10/2022

Chrysanthemic acid is a cyclic organic compound. The product occurs naturally in its ester form in pyrethrum flowers. It is also found as metabolite of pyrenthrins. The acid carries a sweet odor thereby enabling its uses in flavors and is used to synthesize agrochemicals as well.

READ MORE
In focus: Propionic Anhydride
Products in focus · 18/10/2022

Propionic Anhydride is a colorless liquid having a pungent odor and high boiling point. It is miscible with most organic solvents. It is soluble in both water and alcohol. It is a widely used reagent in organic synthesis as well as for producing specialty derivatives of cellulose.

READ MORE
In focus: Colchicine
Products in focus · 04/10/2022

It is an alkaloid used in the symptomatic relief of pain in attacks of gouty arthritis, pseudogout, sarcodial arthritis, calcific tendinitis and to treat the inflammatory symptoms of Familial Mediterranean Fever.
It appears as odourless or nearly odourless pale yellow needles or powder that darkens on exposure to light.

READ MORE
In focus: N-Acetyl-L-Aspartic Acid
Products in focus · 27/09/2022

N-Acetyl-L-aspartic acid, abbreviated as NAA, is second most abundant molecule in nervous systems after amino acid glutamate. It is synthesized in brain from aspartic acid and acetyl co-enzyme A. It also acts as nutrient.

READ MORE