INTRODUCTION

2-Cyclohexene-1-one is an organic intermediate used in synthesis of pharmaceuticals, agrochemicals, and fragrances. It is a ketone, or more precisely, an enone. It undergoes nucleophilic conjugate addition with organocopper reagents, Michael reactions and Robinson annulations.

Manufacture
The product is commercially manufactured by Birch reduction of phenol or anisole, alternatively by catalytic oxidation of cyclohexene.

SynonymsCyclohexenone
Cyclohex-2-enone
CAS no.930-68-7
EINECS no.212-223-5
Molecular formulaC6H8O
Molecular weight96.13
Structure

Applications in Pharma

Cyclohexenone is a key raw material in the production of:
Carprofen, a nonsteroidal anti-inflammatory drug

Applications in Agrochemicals

It is also used to synthesize the herbicides:
Clethodim
Tralkoxydim

Applications in Intermediates

Following intermediates can be synthesized from cyclohexenone:
3-Methylcyclohexanone
2-(Hydroxymethyl)cyclohex-2-en-1-one

Other Applications

As fragrance ingredient with roasted savory green odor
In biological studies for H-tunneling in multiple hydride transfers of catalytic cycle of the enzyme – morphinone reductase

SPECIFICATIONS

TestUnitSpecification
AppearanceClear, colorless or slightly yellowish liquid
Identification by GCPeak in the sample chromatogram to match with that in standard chromatogram
Water by KFw/vMax 0.5
Density at 20°C0.987 – 0.997
Purity by GC%Min 98.0

STORAGE
The product is stored at ambient temperature.

PACKING
25 kg UN-approved carboy.

REACH Status
Not registered yet.

ExSyn offers 2-cyclohexene-1-one on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

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