INTRODUCTION

2-Amino-p-cresol is a crystalline, sublime solid soluble in oxygenated solvents. It serves as an important starting material for production of  colorants and other intermediates.

Manufacture

The compound is produced by nitration of p-cresol and subsequent reduction of the nitro-p-cresol.

Synonyms3-Amino-4-hydroxytoluene
2-Amino-4-methylphenol
CAS no.95-84-1
EINECS no.202-457-3
Molecular formulaC7H9NO
Molecular weight123.16
Structure

Applications in Colorants

The aromatic compound is used to produce colorants such as:

Fluorescent Brightener 135
Fluorescent Brightener PF
Reactive Blue 40
Mordant Green 10

Applications in Intermediates

2-Amino-p-cresol can be converted into the following versatile intermediates:

4-(2-Hydroxy-5-methylphenyl)imino-2-pentanone
N-(2-Hydroxy-5-methylphenyl)-N’-phenylurea
2-Mercapto-5-methylbenzoxazole
2,5-Dimethylbenzoxazole
4-Acetoxy-3-acetyaminotoluene

Other Applications

In synthesis of functionalized spiropyran of benzoxazonone series
As major sensitizer in contact allergy to Disperse Yellow 3

SPECIFICATIONS

TestUnitSpecification
AppearanceClear crystalline powder or crystals with characteristic odor
Solubility in 1% methanol solutionSolution should be clear and light color
Identification by HPLCShould conform to reference chromatogram
Water content%Max 1.5
Sulphated Ash%Max 1.5
Related substances by HPLC
a. 2,6-diaminomethyl-4-phenol%Max 0.2
b. 4-Methyl-3-aminophenol%Max 0.1
c. Any other impurity%Max 0.1
d. Total impurities%Max 0.5
Assay by titration%Min 97

STORAGE
The product is stored under inert atmosphere at ambient temperature.

PACKING
25 kg HDPE drum

ExSyn offers 2-amino-p-cresol on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.

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