INTRODUCTION
2-Amino-p-cresol is a crystalline, sublime solid soluble in oxygenated solvents. It serves as an important starting material for production of colorants and other intermediates.
Manufacture
The compound is produced by nitration of p-cresol and subsequent reduction of the nitro-p-cresol.
| Synonyms | 3-Amino-4-hydroxytoluene 2-Amino-4-methylphenol |
| CAS no. | 95-84-1 |
| EINECS no. | 202-457-3 |
| Molecular formula | C7H9NO |
| Molecular weight | 123.16 |
| Structure |  |
Applications in Colorants
The aromatic compound is used to produce colorants such as:
| Fluorescent Brightener 135 |
| Fluorescent Brightener PF |
| Reactive Blue 40 |
| Mordant Green 10 |
Applications in Intermediates
2-Amino-p-cresol can be converted into the following versatile intermediates:
| 4-(2-Hydroxy-5-methylphenyl)imino-2-pentanone |
| N-(2-Hydroxy-5-methylphenyl)-N’-phenylurea |
| 2-Mercapto-5-methylbenzoxazole |
| 2,5-Dimethylbenzoxazole |
| 4-Acetoxy-3-acetyaminotoluene |
Other Applications
| In synthesis of functionalized spiropyran of benzoxazonone series |
| As major sensitizer in contact allergy to Disperse Yellow 3 |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Clear crystalline powder or crystals with characteristic odor |
| Solubility in 1% methanol solution | – | Solution should be clear and light color |
| Identification by HPLC | – | Should conform to reference chromatogram |
| Water content | % | Max 1.5 |
| Sulphated Ash | % | Max 1.5 |
| Related substances by HPLC | ||
| a. 2,6-diaminomethyl-4-phenol | % | Max 0.2 |
| b. 4-Methyl-3-aminophenol | % | Max 0.1 |
| c. Any other impurity | % | Max 0.1 |
| d. Total impurities | % | Max 0.5 |
| Assay by titration | % | Min 97 |
STORAGE
The product is stored under inert atmosphere at ambient temperature.
PACKING
25 kg HDPE drum
ExSyn offers 2-amino-p-cresol on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
INTRODUCTION Guanosine 5’-diphosphate disodium salt (GDP·Na2) is a purine nucleoside diphosphate that plays a crucial role in various biochemical processes. It is a nucleoside consisting of the base guanine and the sugar riboseIt has two phosphate groups, which affects its function and interactions with enzymes. It is a salt form where two sodium ions are […]
INTRODUCTION Rheological additives are essential components in paint formulations used to control the flow and viscosity of the paint. Modified rheological additives are advanced formulations of traditional rheological additives. They are designed to offer improved performance, versatility, or specific functional properties in applications like paints, coatings etc. Synonym Alkyl quaternary ammonium bentonite CAS no. 68153-34-4 […]
Curcumin, a compound found in turmeric, is known for its anti-inflammatory and antioxidant properties. Introducing 95% curcumin in both human and animal applications involves understanding its high potency, ensuring effective delivery and absorption
Titanium Dioxide (TiO₂) is one of the most important and widely used white pigments in the world. It’s a versatile compound found in an array of products across various industries. Its exceptional properties make it an essential ingredient in everything from paints and coatings to adhesives and cosmetics. TiO₂ exists in two primary grades: Anatase and Rutile.
Hydriodic acid is a strong acid solution of hydrogen iodide in water at nominal concentrations of 47% and 57%. Its stabilized formulation ensures consistent quality and reliability in various applications. This compound often appears as a colorless to pale yellow liquid with a sharp, pungent odor, characteristic of hydrogen halides.
n-Propylamine, known as propylamine in trade, is a versatile primary amine with a lone pair of electrons on nitrogen atom. It makes the amino group reactive and the amine thus undergoes chiefly nucleophilic substitution reactions with substrate.
Iodine is anon-metallic, dark-grey/purple-black, lustrous, solid element. It is the heaviest and the rarest of stable halogens that can be found on the crust of earth.About fifty percent of all iodine produced and manufactured worldwide is used to form Organoiodine compounds. Iodine is an important element for many health-sustaining processes and essential for human thyroid health.
The product, acronymed Oct-NBE, is an organic compound with a cyclic ring system and a 8-membered hydrophobic chain. The structure renders the chemical special properties leading to its applications in diverse fields.
Nicotine is a hygroscopic, colorless to slight yellow, oily liquid, that is readily soluble in alcohol, ether or light petroleum. It is widely used recreationally as a stimulant and anxiolytic.