INTRODUCTION

2-Amino-p-cresol is a crystalline, sublime solid soluble in oxygenated solvents. It serves as an important starting material for production of  colorants and other intermediates.

Manufacture

The compound is produced by nitration of p-cresol and subsequent reduction of the nitro-p-cresol.

Synonyms3-Amino-4-hydroxytoluene
2-Amino-4-methylphenol
CAS no.95-84-1
EINECS no.202-457-3
Molecular formulaC7H9NO
Molecular weight123.16
Structure

Applications in Colorants

The aromatic compound is used to produce colorants such as:

Fluorescent Brightener 135
Fluorescent Brightener PF
Reactive Blue 40
Mordant Green 10

Applications in Intermediates

2-Amino-p-cresol can be converted into the following versatile intermediates:

4-(2-Hydroxy-5-methylphenyl)imino-2-pentanone
N-(2-Hydroxy-5-methylphenyl)-N’-phenylurea
2-Mercapto-5-methylbenzoxazole
2,5-Dimethylbenzoxazole
4-Acetoxy-3-acetyaminotoluene

Other Applications

In synthesis of functionalized spiropyran of benzoxazonone series
As major sensitizer in contact allergy to Disperse Yellow 3

SPECIFICATIONS

TestUnitSpecification
AppearanceClear crystalline powder or crystals with characteristic odor
Solubility in 1% methanol solutionSolution should be clear and light color
Identification by HPLCShould conform to reference chromatogram
Water content%Max 1.5
Sulphated Ash%Max 1.5
Related substances by HPLC
a. 2,6-diaminomethyl-4-phenol%Max 0.2
b. 4-Methyl-3-aminophenol%Max 0.1
c. Any other impurity%Max 0.1
d. Total impurities%Max 0.5
Assay by titration%Min 97

STORAGE
The product is stored under inert atmosphere at ambient temperature.

PACKING
25 kg HDPE drum

ExSyn offers 2-amino-p-cresol on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.

More Products
In focus: Methyl Magnesium Chloride 3M in THF
Products in focus · 24/01/2023

Methyl magnesium chloride is the simplest of Grignard’s reagents. The neat molecule is sensitive to air and moisture. Therefore, it is offered as solution in THF with variable molarity values.

READ MORE
In focus: Polysorbate 20
Products in focus · 17/01/2023

Polysorbate 20 is a gentle, oily, liquid cosmetic additive that functions as a non-ionic surfactant and wetting agent that enhances the spread-ability of liquids.

READ MORE
In focus: Iodomethane
Products in focus · 10/01/2023

Iodomethane, also known as methyl iodide, is a colorless, non-flammable liquid with pungent, ethereal odor that darkens on exposure to light. It occurs naturally in oceans as a product of marine algae.

READ MORE
In focus: 1,4-Dibromobutane
Products in focus · 20/12/2022

1,4-Dibromobutane is a chemical compound from the group of aliphatic, saturated halogenated hydrocarbons. 1,4-Dibromobutane shows similar reactions as the mono-brominated 1-bromobutane, however, in contrast, it is doubly functionalized.

READ MORE
In focus: Tetrabutylammonium fluoride trihydrate
Products in focus · 13/12/2022

Tetrabutylammonium fluoride trihydrate (TBAF trihydrate) is a hygroscopic solid and is a versatile reagent in many chemical reactions. It us usually consumed in aldol-type condensation, Michael-type, and ring opening reactions.

READ MORE
In focus: Pyrophosphoryl Chloride
Products in focus · 29/11/2022

Pyrophosphoryl chloride is colourless to pale yellow liquid, reasonably easy to handle. It reacts violently with water & miscible with most organic solvents.
It is used in pharmaceutical and other organic synthesis, as laser materials and electronic components.

READ MORE
In focus: Benzilic Acid Ethyl Ester
Products in focus · 22/11/2022

Benzilic acid ethyl ester is an oil organic liquid. Its reactivity is attributed to the presence of the hydroxyl group at alpha-position to the carboxylic acid group and hence it participates in various reactions leading to value-added intermediates and APIs.

READ MORE
In focus: Bromobenzene
Products in focus · 15/11/2022

Bromobenzene, an aryl halide, is a clear, colorless liquid with a pleasant odor. It is soluble in methanol and diethyl ether, and very slightly soluble in cold water.

READ MORE
In focus: Dibutyltin Dilaurate
Products in focus · 08/11/2022

Dibutyltin laurate is an organotin compound with oily appearance. The lauric acid ester is used in various industrial applications as catalyst.

READ MORE