INTRODUCTION
1,3-Dimethyl-2-imidazolidinone, popular as DMI solvent, is a high boiling aprotic polar molecule. Apart from being a common solvent in derivative GC, it finds applications in diverse industrial verticals.
Manufacture
The solvent is produced on large scale from ethylenediamine in a multi-step synthesis that also consumes urea, methyl trioctyl ammonium chloride, and dimethyl sulphate as key raw materials.
| Synonyms | N,N’-Dimethylethyleneurea Dimethylimidazolidionone |
| CAS no. | 80-73-9 |
| EINECS no. | 201-304-8 |
| Molecular formula | C5H10N2O |
| Molecular weight | 114.15 |
| Structure |  |
Applications
| DMI solvent is used in synthesis of: |
|---|
| Mirabegron, a drug that eases symptoms of overactive bladder |
| Itraconazole, an anti-fungal API |
| Donepezil, an API to improve memory and awareness in Alzheimer patients |
| Pigment Blue 60 |
| 4-Chloro-1-benzothiophene |
| 2-Fluoro-5-bromobenzonitrile |
| 1,2-Bis(trimethylsilyl)benzene |
| 3,5-Difluorochlorobenzene |
| The solvent is also used as replacement of the toxic solvent hexamethylphosphoramide. |
| It is applied as humectant in cosmetics and its applications in dyestuffs, electronic materials, cellulose, and polymers are also cited. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Colorless to pale yellow liquid |
| Color | APHA | Max 50.0 |
| Specific gravity at 25 deg cel | – | 1.050 – 1.060 |
| Refractive index | – | 1.468 – 1.473 |
| Moisture by KF | % | Max 1.0 |
| Purity by GC | % | Min 99.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
200 kg HDPE drum.
REACH Status
Not Registered yet.
ExSyn offers 1,3-dimethylimidazolidin-2-one on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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