INTRODUCTION
The bi-naphthol moiety is a colorless solid. The structure depicts two naphthol rings joined at the respective 1-positions. The presence of two hydroxy groups renders the molecule highly reactive and the product forms a backbone of a variety of value-added chemicals and ligands.
Synonyms | 1,1’-bi-2-naphthol |
CAS no. | 602-09-5 |
EINECS no. | 210-014-0 |
Molecular formula | C2OH14O2 |
Structure | (download pdf to view) |
Molecular weight | 286.32 |
APPLICATIONS
The bi-naphthyl structure serves as an important ligand for asymmetric synthesis in organic chemistry, especially in Diels-Alder reactions, carbonyl addition and reductions.
Some key applications are:
2,2’-bis(diphenylphosphino)-1,1’-binaphthyl (BINAP) |
(S)-Binol by resolution of the mother binol |
(R)-Binol in the same resolution process |
Aluminium Lithium bi(binaphthol) (its (R)-enantiomer) |
(S)-Vanol |
A very recent but path-breaking application of Binol has been in preparation of one of the Covid-19 vaccines being developed and supplied from India.
SPECIFICATIONS
TEST | UNIT | SPECIFICATION |
---|---|---|
Appearance | – | White to off-white powder |
Identification By IR | – | Conforms to reference spectrum |
Identification By Proton NMR | – | Conforms to reference spectrum |
Purity By HPLC | % | NLT 99.0 |
Moisture | Wt. % | NMT 0.5 |
STORAGE
The product is stored at ambient temperature.
ExSyn offers this compound on commercial scale and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
1-(Difluoromethyl)-4-nitro-1H-pyrazole is a difluoromethyl aromatic compound with an active nitro group for reduction. It is used as an organic synthesis key starting material and intermediate in APIs.
1-Bromohexane is an organic liquid belonging to the category of alkyl bromides or bromoalkanes. Its reactivity is due to presence of bromine in the allylic position. Apart from being a useful solvent in organic synthesis, it is used in synthesis of various intermediates.
Valeryl chloride is an organic liquid belonging to the category – acid chloride. It is a versatile reagent in organic syntheses leading to its diverse applications such as synthesis of enzyme inhibitors, production of APIs, intermediates, and agrochemicals.
2-Chloroethylamine hydrochloride is a colourless to off-white solid. It consists of an alkylamine attached to a Chlorine atom. It is a member of the Chloroalkylamines. It is a highly corrosive material to both skin and metals thus it must be handled with extreme care.
Thiophosgene is an organic liquid with a heterogeneous composition. The molecule is a reactive electrophile leading to its applications in APIs, intermediates, and agrochemicals, amongst others.
N.N’-Dicyclohexylcarbodiimide, acronymed as DCCD by chemists, is a versatile reagent in organic syntheses. Its reactivity is due to the presence of carbodiimide group in its structure.
Sodium bromide is an inorganic compound with the formula NaBr. It is a high-melting white, crystalline solid that resembles sodium chloride. It is a widely used source of the bromide ion and has many applications.
3,5-Dibromo-4-hydroxybenzoic acid is an alkylated aromatic compound with active bromo groups. They enable its multiple usages such as organic synthesis reagent, biological stain, and enzyme inhibitor. The compound is also a key intermediate in production of APIs.
Bakuchiol is known as Vegan Retinol as it has ability to improve uneven skin tone by reducing the appearance of dark spots and pigmentation. It is best in class of anti-aging and anti-wrinkles effect.