INTRODUCTION
Pyridinium tribromide, an organic solid from the category of heterocyclic halides, is a highly efficient and selective bromination agent in organic syntheses. It is also used in production of APIs and intermediates.
Manufacture
It is produced by excessive bromination of pyridine HBr.
| Synonyms | Pyridine HBr perbromide Monopyridine-1-ium tribromide |
| CAS no. | 39416-48-3 |
| EINECS no. | 254-446-8 |
| Molecular formula | C5H6Br3N |
| Molecular weight | 319.82 |
| Structure | ![]() |
Applications
| APIs |
|---|
| Dienogest, an oral progestin |
| Cefteram, an antibiotic |
| Intermediates |
|---|
| 4-Bromo-1-chloroisoquinoline |
| Mes-stilbene dibromide |
| Phosphorous tribromide |
| Others |
|---|
| In alpha-bromination of ketones, phenols, ethers, and unsaturated compounds |
| In studies concerning bromine incorporation into organic pollutants for environmental impact assessment |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Dark orange to brown crystalline powder with odour of bromine |
| Identification by IR | – | The IR spectrum of the sample should be concordant with that of the standard |
| Solubility | – | Soluble in methanol |
| Melting point | OC | 128 – 136 |
| Available bromine | % w/w | 45 – 50 |
| Assay | % | Min 95.0 |
STORAGE
Product is stored at ambient temperature.
PACKING
25 kg UN-approved HDPE drum with double HDPE liner
REACH STATUS
Not registered
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