INTRODUCTION
Pyridine hydrobromide is a white to off-white hygroscopic crystalline solid with melting point/freezing point of 216 °C to 219 °C. It is miscible in water. It used in many chemical synthesis studies.
Manufacture
It is manufactured by the reaction of pyridine with hydrogen bromide.
| Synonyms | Pyridinium bromide |
| CAS no. | 18820-82-1 |
| EINECS no. | 242-600-7 |
| Molecular formula | C5H6BrN |
| Molecular weight | 160.01 |
| Structure |  |
Applications
| Pyridine hydrobromide is used as an intermediate in the chemical industry for the manufacturing of active pharmaceutical ingredients like antibiotics, Cephalosporin & Cephalexin. |
| Also used in Mouthwash (Oral care), Skin Cream (Cosmetic). |
| It is quite useful for bromination of ketones. |
| It is used as an electrolyte in the electrochemical cells. It has been shown to inhibit the activity of cytochrome P450 enzymes, which are important for the metabolism of xenobiotic compounds. |
| Pyridine hydrobromide has also been shown to have synergistic effects with other drugs, such as sodium carbonate and l-arabinose, in inhibiting the growth of bacteria in vitro and in vivo. |
| This compound is also able to form acid complexes with metal ions such as zinc and copper, which may be useful for therapeutic purposes where coordination geometry is important. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description | – | White to off-white to pale brown crystalline powder, Hygroscopic. Faint odour of Pyridine |
| Identification (by Chemical) | – | Pale yellow precipitate should be formed |
| Solubility | – | Freely soluble in Methanol, Ethanol and Water |
| pH (5% solution) | w/v | 2.0 – 3.0 |
| Water (by KF) | % | NMT 0.2 |
| Melting Point | °C | 216 – 219 |
| Free Pyridine | % w/w | NMT 0.3 |
| Assay (by Titration) | % | 99.0 – 101.0 |
STORAGE
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, water, moisture.
PACKING
50 kg HDPE drum.
REACH Status
Not registered yet.
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