INTRODUCTION
N-Acetyl-L-aspartic acid, abbreviated as NAA, is second most abundant molecule in nervous systems after amino acid glutamate. It is synthesized in brain from aspartic acid and acetyl co-enzyme A. It also acts as nutrient.
Manufacture
In a biological process, NAA is produced from rat brain acetone. Commercially, it is manufactured by acetylation of L-aspartic acid bis(trimethylsilyl)ester using acetyl chloride.
| Synonyms | N-Acetyl aspartate NAA |
| CAS no. | 997-55-7 |
| EINECS no. | 213-643-9 |
| Molecular formula | C6H9NO5 |
| Molecular weight | 175.14 |
| Structure |  |
Applications in Synthesis
| The chiral acid is used to synthesize: |
|---|
| Its anhydride |
| Homoserine gamma-lactones |
Other Applications
| As reagent in selective reductions of cyclic ketones |
| In acid-catalyzed cyclization reactions |
| In peptide synthesis |
| As a nutraceutical supplement in capsule, tablet, and liquid dosage form |
| As antioxidant |
| As human and rat metabolites |
| Isotopic form used in studies for metabolic alteration associated with schizophrenia |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | White powder |
| Specific rotation (C = 1, HAc) | Degree | 50.0 – 54.0 |
| Water | % | Max 0.5 |
| Assay | % | Min 98.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
25 kg Fibre drum.
REACH Status
Not Registered yet.
ExSyn offers N-acetyl-L-aspartic acid on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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