INTRODUCTION
Dichloroacetyl chloride, acronymed DCAC, is an organic solvent that belongs to the category of acid chlorides. Its uses include manufacture of APIs, agrochemicals, and a series of intermediates. It is also applied in synthesis of biologically active compounds.
Manufacture
It is commercially manufactured by chlorination of dichloroacetic acid with chlorosulphonic acid.
| Synonym | DCAC alpha,alpha-Dichloroacetyl chloride |
| CAS no. | 79-36-7 |
| EINECS no | 201-199-9 |
| Molecular formula | C2HCl3O |
| Molecular weight | 147.39 |
| Structure |  |
Applications
| API – DCAC is a KRM in manufacture of: |
|---|
| Chloramphenicol, an antibiotic |
| Intermediates – The acid chloride is used in manufacture of intermediates such as: |
|---|
| 4-Methyltroplone |
| 4’-Hydroxy-3’-methoxyacetophenone |
| (RS)-3-Dichloroacetyl-5-(2-furanyl)-2,2-dimethyl-1,3-oxazolidine |
| Tetrachloroacetyl chloride |
| Agrochemicals – Dichloroacetyl chloride is used in production of various agrochemicals such as: |
|---|
| Tetrachlorovinphos, an insecticide |
| Heptenophos, also an insecticide |
| Benoxocar, a herbicide |
| Flurochloridon, also a herbicide |
| Others |
|---|
| In protection of oxindoles |
| In synthesis of substituted benzothiazoles |
| In synthesis of biologically active compounds like hormones and enzymes |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Colourless liquid |
| Identification by IR | – | Should conform to the reference standard |
| Boiling Range | °C | 107.0 – 108.0 |
| Assay | % | Min 98.0 |
STORAGE
Stored at ambient temperature
PACKING
250 kg UN-approved Composite drum
REACH Status
Not registered
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