INTRODUCTION
A fluorinated heterocyclic which is a liquid with a halo-substituent at 4-position with respect to fluorine. The bromine atom in this case chiefly participates in condensation reactions with other chemicals that lead to an array of important intermediates, which are in turn used for various applications.
| Synonyms | 5-Bromo-2-Fluoropyridine |
| CAS no. | 766-11-0 |
| EINECS no. | 629-380-1 |
| Molecular formula | C5H3N3BrFN |
| Structure | (download pdf to view) |
| Molecular weight | 175.99 |
APPLICATIONS
This compound acts as a lead to many vital intermediates leading to syntheses of a range of APIs. Its application in peptide synthesis is also cited, which is likely to further boost demand.
Pharmaceuticals
| Intermediate | CAS no. |
| 5-bromo-2-fluoropyridine-3-carboxaldehyde | 875781-15-0 |
| 2-Fluoro-3-formylpyridine | 36404-90-7 |
| 2-Fluoro-5-bromopyridine-3-boronic acid | 501435-91-2 |
| 2-Fluoro-5-hydroxypyridine | 55758-32-2 |
| (3R)-3-(3-[(5-Brpyrdn-2-yl)oxylphenyl])-1-oxa-8-azaspiro[4.5]-decane-8-carboxamide | – |
| 5-Bromo-1H-pyrazolo[3,4-b]pyridine | 875781-17-2 |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Pale yellow to light brown liquid |
| Identification By GC | – | The retention time of the principal peak obtained with sample solution should match with that of working standard |
| Purity By GC | % | Min 98.0 |
| Moisture | Wt % | Max 0.5 |
STORAGE
The product is stored at ambient temperature.
ExSyn offers this compound on commercial scale and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.
Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate is a fluorinated aliphatic hydroxy ester. The presence of the trifluoromethyl group imparts enhanced metabolic stability, lipophilicity, and unique physicochemical properties compared with non-fluorinated analogues. This compound is primarily used as a synthetic intermediate in pharmaceutical and agrochemical research.
2-Chloro-1,1,1-trimethoxyethane is an organochlorine orthoester compound commonly used as a versatile synthetic intermediate in organic and pharmaceutical chemistry. It is a colorless to pale yellow liquid with good reactivity toward nucleophilic substitution and cyclization reactions, making it valuable in the preparation of heterocyclic and bioactive molecules.
Glycolaldehyde dimer is the cyclic dimeric form of glycolaldehyde, the simplest hydroxyaldehyde. Glycolaldehyde is often supplied as stable dimeric solid, commonly identified as 2,5-dihydroxy-1,4-dioxane.
N,N-Diisopropylethylamine (DIPEA), also known as Hünig’s Base, is a sterically hindered tertiary amine. It is a colorless liquid with a strong amine odor and is widely used as a low nucleophilic organic base in pharmaceutical, agrochemical, and fine chemical synthesis. Due to its bulky structure, DIPEA effectively scavenges acids without participating in unwanted side reactions.
Tris(2,4-di-tert-butylphenyl) phosphite (TDPP) often recognized commercially as Irgafos 168 is a high-performance organophosphorus compound primarily utilized as secondary antioxidant and processing stabilizer. Its characteristic to undergo metallation reaction and provide a cost-effective synthetic processes allows it to be useful in biaryl coupling reactions.
Undecylenic acid is an unsaturated fatty acid naturally derived from castor oil. It is a colorless to pale yellow liquid with antifungal and antimicrobial properties. Chemically known as 10-undecenoic acid, it contains an 11-carbon chain with one double bond and is widely used in pharmaceuticals
5-Nitro Isophthalic Acid (5-NIPA) is an aromatic organic compound derived from isophthalic acid. The presence of two carboxylic acid groups along with a nitro substituent at the 5-position makes it a valuable intermediate in the manufacture of fine chemicals, pharmaceuticals, dyes, pigments, and advanced materials.
Trichloroacetonitrile is a halogenated organic compound belonging to nitrile family. Its strong electrophilic character makes it a valuable intermediate in organic synthesis. It readily undergoes hydrolysis, particularly under acidic or basic conditions, yielding trichloroacetamide and related derivatives.