INTRODUCTION
A fluorinated heterocyclic which is a liquid with a halo-substituent at 4-position with respect to fluorine. The bromine atom in this case chiefly participates in condensation reactions with other chemicals that lead to an array of important intermediates, which are in turn used for various applications.
| Synonyms | 5-Bromo-2-Fluoropyridine |
| CAS no. | 766-11-0 |
| EINECS no. | 629-380-1 |
| Molecular formula | C5H3N3BrFN |
| Structure | (download pdf to view) |
| Molecular weight | 175.99 |
APPLICATIONS
This compound acts as a lead to many vital intermediates leading to syntheses of a range of APIs. Its application in peptide synthesis is also cited, which is likely to further boost demand.
Pharmaceuticals
| Intermediate | CAS no. |
| 5-bromo-2-fluoropyridine-3-carboxaldehyde | 875781-15-0 |
| 2-Fluoro-3-formylpyridine | 36404-90-7 |
| 2-Fluoro-5-bromopyridine-3-boronic acid | 501435-91-2 |
| 2-Fluoro-5-hydroxypyridine | 55758-32-2 |
| (3R)-3-(3-[(5-Brpyrdn-2-yl)oxylphenyl])-1-oxa-8-azaspiro[4.5]-decane-8-carboxamide | – |
| 5-Bromo-1H-pyrazolo[3,4-b]pyridine | 875781-17-2 |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Pale yellow to light brown liquid |
| Identification By GC | – | The retention time of the principal peak obtained with sample solution should match with that of working standard |
| Purity By GC | % | Min 98.0 |
| Moisture | Wt % | Max 0.5 |
STORAGE
The product is stored at ambient temperature.
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