INTRODUCTION

Pyrophosphoryl Tetrachloride is a colorless fuming corrosive liquid .It consists of a pyrophosphate (a molecule with a P-O-P bond) group, where one phosphorus atom is bonded to four chlorine atoms and the other is bonded to three chlorine atoms. It is a reactive chemical compound and should be handled with care. Commonly used in the synthesis of other phosphorus-containing compounds and as a chlorinating agent in organic chemistry

Manufacture

It is manufactured by chlorination of Phosphorous Pentoxide with Phosphorous Trichloride followed by distillation process.

SynonymDiphosphoric Tetrachloride; Pyrophosphoryl Chloride
CAS #13498-14-1
EINECS #236-824-4
Molecular formulaCl4O3P2
Molecular weight251.76
Structure

Applications

Pyrophosphoryl Tetrachloride has several specialized applications.

Pharmaceutical
As reductive chlorinating reagent in synthesis of Quetiapine
Acts as a phosphorylating agent involved in nucleoside synthesis. 
Organophosphorus Compounds
Used to prepare Organophosphorus compounds which are widely used in;
Pesticides and herbicide
Flame retardants
Plasticizers
Catalyst
Can be used in phosphorylation of reactants, which can facilitate or promote certain reaction pathways.
Phosphorous Compounds
Serves as a precursor or intermediate in the synthesis of other more complex phosphorus compounds through;
Phosphorylation reactions in the synthesis of certain phosphoryl esters or phosphoric acid derivatives.
Phosphorus oxychloride derivatives
Others
Used as a chlorinating agent

SPECIFICATIONS

TestUnitSpecifications
AppearanceColorless, smoking, corrosive liquid
Density (at 20 °C)1.80 -1.82
Assay (By Chloride)NLT 99
Assay (By Acidimetric)%NLT 99

STORAGE & PRECAUTION

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Reactive fuming corrosive liquid, do not allow product to get in contact with water during storage.

PACKING

2.5 Litre Amber colored glass bottles (Equivalent to 4 kg material)

REACH Status

Not registered

ExSyn offers Pyrophosphoryl Tetrachloride on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Glyceryl Stearate Citrate
Products in focus · 25/11/2025

Glyceryl Stearate Citrate (GSC) is a plant-derived, biodegradable emulsifier commonly used in cosmetics and personal-care products. It functions primarily as an anionic oil-in-water (O/W) emulsifier, helping blend oils and water into smooth, stable creams and lotions. Its natural origin and gentle profile make it popular in eco-certified, organic, and sensitive-skin formulations.

READ MORE
In focus: DL-Serine
Products in focus · 18/11/2025

DL-Serine is a racemic mixture of both the D- and L-forms of the amino acid serine, which is a polar, nonessential amino acid. It  is an α-amino acid characterized by its hydroxyl-containing side chain, which enables it to take part in numerous biochemical reactions and synthetic processes. It functions as a pivotal intermediate in the biosynthesis of amino acids, including glycine and cysteine, underscoring its essential role in cellular metabolism. Moreover, it constitutes a critical pharmaceutical intermediate for the synthesis of a broad spectrum of therapeutic agents and drug candidates.

READ MORE
In focus: Ethyl Vinyl Ether (EVE)
Products in focus · 11/11/2025

Ethyl vinyl ether is a reactive, flammable, volatile liquid with a strong ether-like odor. Featuring two conjugated functional groups—an ether and an alkene—this molecule act as important building block, especially in polymer synthesis. Its applications span multiple industrial sectors, including semiconductors, coatings, inks, fragrances, adhesives, paints, oil viscosity modifiers and pharmaceuticals, with promising potential as a dietary supplement.

READ MORE
In focus: Peppermint Microencapsulated Powder
Products in focus · 04/11/2025

Peppermint (Mentha piperita) is a common herb, also known as a hybrid mint. Its main components are oxygenated monoterpenes: alcohols, esters and ketones. Peppermint oleoresin microencapsulated powder is a white to off-white coloured powder produced from the seeds of the plant. In order to protect and maintain the stability of peppermint oil, microencapsulation is carried out through process  optimization using the coacervation technique. This technique helps limit the loss and degradation of flavours and aromas during processing and storage. It offers versatile applications across multiple industries — from food and beverages to pharmaceuticals, cosmetics, and textiles.

READ MORE
In focus: 5-Methyl-3-vinyl-2-oxazolidinone
Products in focus · 14/10/2025

5-Methyl-3-vinyl-2-oxazolidinone (V-MOX) is a highly reactive monomer valued for its low viscosity, mild odor, and excellent reactivity. It is widely used as a reactive diluent in UV-curable inks and coatings, where it enhances adhesion, produces brighter colors, and improves safety compared to conventional diluents. In addition, V-MOX serves as a key building block in the synthesis of kinetic hydrate inhibitor (KHI) polymers, which are applied in oil and gas production to prevent hydrate blockages in pipelines.

READ MORE
In focus: Zinc Ricinoleate
Products in focus · 07/10/2025

Zinc ricinoleate is the zinc salt of ricinoleic acid, a hydroxylated fatty acid derived mainly from castor oil (Ricinus communis). It appears as a white to slightly yellowish powder, waxy solid, or paste, depending on formulation. Its most valuable property is its ability to trap and absorb odor molecules such as amines, sulfides, and short-chain fatty acids, making it an essential ingredient in deodorant and odor-control products.

READ MORE
In focus: 2- (tert – Butylamino) Ethyl Methacrylate
Products in focus · 30/09/2025

2-(tert-Butyl amino)ethyl methacrylate (TBAEMA) is a functional methacrylate monomer that contains a secondary amine group and a hydrophobic tert-butyl moiety, giving it excellent versatility in pH-responsive and adhesion-enhancing polymer systems.
It is valued in printing ink formulations for its ability to enhance adhesion, flexibility, and surface interaction.

READ MORE
In focus: 1,1,2,2,3,3-Hexafluoropropane-1,3-disulfonimide Potassium Salt
Products in focus · 23/09/2025

Commonly known as potassium bis(fluorosulfonyl)imide (KFSI), the compound has a three-carbon backbone bearing six fluorine atoms and two sulfonimide (-SO₂F) groups. The molecule’s architecture lends it both high chemical stability and useful reactivity. Because of its excellent ionic conductivity and thermal / electrochemical stability, it finds use in advanced electrolyte formulations—for example in lithium-ion and next-generation batteries, in ionic liquids, and in other electrochemical systems.

READ MORE
In focus: Colchicine
Products in focus · 09/09/2025

Colchicine is a naturally occurring alkaloid obtained primarily from the autumn crocus (Colchicum autumnale) and related species. It has been used in medicine for centuries, especially for the treatment of gout and Familial Mediterranean Fever. In modern medicine, Colchicine is valued also in conditions like pericarditis, Behçet’s disease, and certain dermatological and cardiac disorders.

READ MORE