INTRODUCTION
Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. Piperazine exists as small alkaline deliquescent crystals with a saline taste. Piperazine is supplied as (anhydrous) Piperazine 99%.
Manufacture
Piperazine is generally prepared by treating ammonia with ethylene diamine, amino ethyl ethylene diamine, monoethanol amine or diethanol amine; or hydrogenation of N-(amino ethyl) ethanol amine.
| Synonyms | Diethylenediamine 1,4-Diazacyclohexane Hexahydropyrazine Piperazidine |
| CAS no. | 110-85-0 |
| EINECS no. | 203-808-3 |
| Molecular formula | C4H10N2 |
| Molecular weight | 86.14 |
| Structure |  |
| Applications |
|---|
| Used as a raw material for the manufacture of quinolone drugs like Ciprofloxacin and Norfloxacin. |
| Also used in manufacture of other drugs like Anthelmintics, Sedatives, Antihistamines, Antifilarials, Tranquilizers, and Analgesics. |
| As an intermediate in the preparation of: – Hydroxyethyl piperazine – N,N’-dimethyl piperazine – N-methyl piperazine |
| Used for speciality chemicals and polymeric products like corrosion inhibitors, photographic chemicals, wetting agents, polyamides, rubber auxiliaries and hardener for epoxy resins and Gas sweetening. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | White to off-white flakes with hygroscopic nature |
| Solubility | – | Freely soluble in water and in ethanol, practically insoluble in ether |
| Water content (by KF) | % w/w | NMT 1.0 |
| Purity (by GC) | % | NLT 99.0 |
STORAGE
Store in a dry and well-ventilated area. Ambient temperatures.
PACKING
25 kg UN approved drums.
REACH status
Not registered yet.
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