Racemic quinuclidinol is an off-white solid that possesses medicinal properties. It is an alkaloid abundant in nature, especially in Erythroxylum coca. Synthetically manufactured product finds usage in APIs, intermediates, and medicinal chemistry.
It is commercially manufactured by optical resolution of 3-quinuclidinol, the by-product being (R)-(-)-3-quinuclidinol.
|Quinuclidinol is used in the manufacture of following APIs|
|Solifenacin HCl, treats urinary inconsistence|
|Clidinium, an anticholinergic drug|
|Umeclidinium, to treat shortness of breath|
|Penehyclidine HCl, a selective anticholinergic|
|Solifenacin succinate, an antimuscarinic agent|
|As reagent in chemoselective alpha-iodination of acrylic esters and for cleavage of beta-keto esters|
|As synthon for preparation of cholinergic receptor ligands and anesthetics|
|Appearance||–||Cream coloured to off-white solid|
|Melting range||°C||210.0 – 220.0|
|LOD at 50 °C||%||Max 1.0|
|Purity by GC||%||Min 95.0|
|Purity by Chiral HPLC||%||Min 99.0|
Stored at ambient temperature.
25 kg UN approved HDPE drum.
Not registered yet.
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