INTRODUCTION

Pyridine hydrobromide is a white to off-white hygroscopic crystalline solid with melting point/freezing point of 216 °C to 219 °C. It is miscible in water. It used in many chemical synthesis studies.

Manufacture
It is manufactured by the reaction of pyridine with hydrogen bromide.

SynonymsPyridinium bromide
CAS no.18820-82-1
EINECS no.242-600-7
Molecular formulaC5H6BrN
Molecular weight160.01
Structure

Applications

Pyridine hydrobromide is used as an intermediate in the chemical industry for the manufacturing of active pharmaceutical ingredients like antibiotics, Cephalosporin & Cephalexin.
Also used in Mouthwash (Oral care), Skin Cream (Cosmetic).
It is quite useful for bromination of ketones.
It is used as an electrolyte in the electrochemical cells. It has been shown to inhibit the activity of cytochrome P450 enzymes, which are important for the metabolism of xenobiotic compounds.
Pyridine hydrobromide has also been shown to have synergistic effects with other drugs, such as sodium carbonate and l-arabinose, in inhibiting the growth of bacteria in vitro and in vivo.
This compound is also able to form acid complexes with metal ions such as zinc and copper, which may be useful for therapeutic purposes where coordination geometry is important.

SPECIFICATIONS

TestUnitSpecification
DescriptionWhite to off-white to pale brown crystalline powder, Hygroscopic. Faint odour of Pyridine
Identification (by Chemical)Pale yellow precipitate should be formed
SolubilityFreely soluble in Methanol, Ethanol and Water
pH (5% solution)w/v2.0 – 3.0
Water (by KF)%NMT 0.2
Melting Point°C216 – 219
Free Pyridine% w/wNMT 0.3
Assay (by Titration)%99.0 – 101.0

STORAGE
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, water, moisture.

PACKING
50 kg HDPE drum.

REACH Status
Not registered yet.

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