INTRODUCTION
The heterocyclic is a liquid that serves as one of main coupling agents in the peptides and polypeptides production. The molecule is already activated by the presence of the aldehyde group and hence reacts readily in number of reactions.
| Synonyms | Nicotinaldehyde, Pyridine-3-Carbaldhyde |
| CAS no. | 500-22-1 |
| EINECS no. | 207-900-4 |
| Molecular formula | C6H5NO |
| Structure | (download pdf to view) |
| Molecular weight | 107.11 |
APPLICATIONS
This compound finds wide applications across various industry segments.
Peptides and Polypeptides
As a KRM for peptides and coupling agent for a broad spectrum of polypeptides manufactured by solid state synthesis. These include Abarelix, Cetroreix and Ganirelix.
Pharmaceuticals
Pyridine-3-carboxaldehyde serves as a building block in synthesis of number of APIs such as antiretroviral protease inhibitor used in the battle against HIV, glycoprotein antagonist, etc.
| API | Therapeutic Category |
| Indinavir | Anti-retroviral |
| Elarofiban | Thrombosis management |
| Seletalisib | Immunomodulator |
| Xanomeline Oxalate | CNS |
| Paroxetine HCl | CNS |
Agrochemicals
The compound is also a KRM in manufacture of:
a) Pymetrozine, an insecticide and a xenobiotic
b) Pyrifenox, a fungicide
Intermediates
A series of value-added intermediates can also be synthesized by using nicotinaldehyde.
These include:
a) Pyridin-3-yl-methylhydrazine
b) 3-(Pyridin-3-yl)propanal
c) (S)-N- Boc -(3pyridyl)alanine
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Pale yellow to brown liquid |
| Identification By GC | – | The retention time of the major peak of sample corresponds to that of standard |
| Purity By GC | % | NLT 98.0 |
STORAGE
The product is stored at ambient temperature.
ExSyn offers this compound on commercial scale and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Colchicine is a naturally occurring alkaloid obtained primarily from the autumn crocus (Colchicum autumnale) and related species. It has been used in medicine for centuries, especially for the treatment of gout and Familial Mediterranean Fever. In modern medicine, Colchicine is valued also in conditions like pericarditis, Behçet’s disease, and certain dermatological and cardiac disorders.
1-Butylimidazole is a versatile organic heterocyclic compound belonging to the imidazole family, where a butyl group (–CH₂–CH₂–CH₂–CH₃) is attached to the nitrogen atom at the 1-position of the imidazole ring. Its applications span organic synthesis, materials science, and bioactive compound development due to its tunable physicochemical properties and structural versatility.
Atropine sulfate monohydrate is a chemical compound, specifically a salt of atropine and sulfuric acid, with one water molecule (monohydrate) attached. It is commonly used as a medication and in research due to its anticholinergic properties, meaning it blocks the effects of acetylcholine at muscarinic receptors.
4-Aminobenzoic acid, commonly abbreviated as PABA, is an aromatic amine and carboxylic acid compound. It consists of a benzene ring substituted with an amino group (–NH₂) in the para position to a carboxylic acid group (–COOH).
2-Amino-5-Nitrophenol (5-NAP) is an organic compound with the molecular formula C₆H₆N₂O₃. It is a substituted phenol with both an amino group (-NH₂) and a nitro group (-NO₂) attached to a benzene ring, along with a hydroxyl group (-OH).
Pongamol is a naturally occurring flavonoid primarily extracted from the seeds and leaves of the Pongamia pinnata tree (also known as Karanja tree), native to South and Southeast Asia. It is a cream-colored compound that belongs to the flavonoid family and is known for its antioxidant, anti-inflammatory, antimicrobial, and pesticidal properties. It is one of the key bioactive constituents of Pongamia oil.
Biobased Ethyl Acetate is an environmentally friendly solvent made from renewable sources like bioethanol extracted from sugarcane, corn, and other forms of biomass. Unlike traditional ethyl acetate, which is typically derived from fossil fuels, this green alternative shares the same chemical structure (C₄H₈O₂) and functional performance—offering comparable versatility with a significantly lower environmental footprint.
Palmitoyl chloride is a long-chain fatty acid derivative. It is the acid chloride form of palmitic acid; a saturated fatty acid commonly found in palm oil and other natural fats. It appears as a colorless to pale yellow liquid with a sharp odour and is highly reactive, especially toward water, alcohols, and amines.
Fungal Lycopene is an acyclic carotene belonging to a large group of naturally-occurring pigments known as carotenoids. It contains at least 90% of all-trans-lycopene and minor quantities of 13-cis-lycopene and β- and γ-carotene. It is used as an intermediate in the biosynthetic pathway of β-carotene. Its role in the pharmaceutical and food industries stems from its demonstrated health benefits—such as anticancer and cardiovascular protection—alongside its widespread use as a natural food colorant.