INTRODUCTION

Permethrin is an insecticide in the pyrethroid family. Pyrethroids are synthetic chemicals that act like natural extracts from the chrysanthemum flower.

Manufacture
Permethrin is produced by condensation of 3-phenoxybenzyl alcohol with (1RS)-cis/trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid.

Synonyms3- (2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid (3 –phenoxyphenyl)-methyl ester; 3-phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
CAS no.52645-53-1
EINECS no.258-067-9
Molecular formulaC21H20Cl2O3
Molecular weight391.3
Structure

APPLICATIONS

Permethrin is used in agricultural, textile, food and pharma industries. Some of the key applications where it is used are:

Insecticide
to protect crops & to kill livestock parasites
on structures and buildings, including livestock housing and food-handling establishments. Permethrin can also be used in numerous residential sites, both indoor and outdoor and on pets
to prevent insect attack on woollen products
in aircraft disinfection

Insect repellant
as a personal protective measure, permethrin is applied to clothing. It is a cloth impregnant, notably in mosquito nets and field wear.
while permethrin may be marketed as an insect repellent, it doesn’t prevent insects from landing. Instead, it works by incapacitating or killing insects before they can bite.
in pet flea preventive collars or treatment (safe for use on dogs but not cats)
in timber treatment

Medicinal
available for topical use as a cream or lotion
used for the treatment and prevention in exposed individuals of head lice
used as a medication in the treatment of scabies in humans and animals

SPECIFICATIONS – EP

TestUnitSpecification
AppearanceColorless or slightly brownish viscous liquid, semi solid or crystalline solid.
SolubilityPractically insoluble in water, very soluble in heptane, freely soluble in anhydrous ethanol, sparingly soluble in ethylene glycol.
Identification

– by IR

– by HPLC





IR Spectrum exhibits maxima which are only at the same wave number as those in “Reference Spectrum of Permethrin Reference Standard“

The 2 Principal peaks in the chromatogram obtained with the test solution are similar in retention time and in cis/trans ratio to the 2 principal peaks in the chromatogram obtained with the reference solution
Water (by KF)%NMT 0.25
Sulphated Ash%NMT 0.1
Related Substances (by GC)
– Impurity B
– Impurity C
– Impurity G
– Unspecified Impurities
– Total Impurity

%
%
%
%
%

NMT 0.15
NMT 0.15
NMT 0.10
NMT 0.10
NMT 0.50
Residual Solvent
– IPA
– Toluene
 – DMF
– *Benzene

ppm
ppm
ppm
ppm

NMT 5000
NMT 890
NMT 880
NMT 2
Assay (on anhydrous basis)%98.0 – 102.0
Cis isomer%23.0 – 27.0
Trans isomer%73.0 – 77.0
Note : Before sampling stir well & warm up to 40⁰C Permethrin solidifies below 35⁰C. In case of solidification please warm up to 70 to 80⁰C to get liquid (Before use). This does not affect the quality
*Benzene is not used in process, but tested due to the use of Toluene

PACKAGING OPTIONS
25 Kg HDPE Drums

STORAGE
Store in a sheltered place away from sources of heat and moisture

CERTIFICATION
WHO-GMP, DMF & CEP

No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.

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