INTRODUCTION
Permethrin is an insecticide in the pyrethroid family. Pyrethroids are synthetic chemicals that act like natural extracts from the chrysanthemum flower.
Manufacture
Permethrin is produced by condensation of 3-phenoxybenzyl alcohol with (1RS)-cis/trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid.
| Synonyms | 3- (2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid (3 –phenoxyphenyl)-methyl ester; 3-phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| CAS no. | 52645-53-1 |
| EINECS no. | 258-067-9 |
| Molecular formula | C21H20Cl2O3 |
| Molecular weight | 391.3 |
| Structure |  |
APPLICATIONS
Permethrin is used in agricultural, textile, food and pharma industries. Some of the key applications where it is used are:
| Insecticide |
|---|
| to protect crops & to kill livestock parasites |
| on structures and buildings, including livestock housing and food-handling establishments. Permethrin can also be used in numerous residential sites, both indoor and outdoor and on pets |
| to prevent insect attack on woollen products |
| in aircraft disinfection |
| Insect repellant |
|---|
| as a personal protective measure, permethrin is applied to clothing. It is a cloth impregnant, notably in mosquito nets and field wear. |
| while permethrin may be marketed as an insect repellent, it doesn’t prevent insects from landing. Instead, it works by incapacitating or killing insects before they can bite. |
| in pet flea preventive collars or treatment (safe for use on dogs but not cats) |
| in timber treatment |
| Medicinal |
|---|
| available for topical use as a cream or lotion |
| used for the treatment and prevention in exposed individuals of head lice |
| used as a medication in the treatment of scabies in humans and animals |
SPECIFICATIONS – EP
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Colorless or slightly brownish viscous liquid, semi solid or crystalline solid. |
| Solubility | – | Practically insoluble in water, very soluble in heptane, freely soluble in anhydrous ethanol, sparingly soluble in ethylene glycol. |
| Identification – by IR – by HPLC | – – | IR Spectrum exhibits maxima which are only at the same wave number as those in “Reference Spectrum of Permethrin Reference Standard“ The 2 Principal peaks in the chromatogram obtained with the test solution are similar in retention time and in cis/trans ratio to the 2 principal peaks in the chromatogram obtained with the reference solution |
| Water (by KF) | % | NMT 0.25 |
| Sulphated Ash | % | NMT 0.1 |
| Related Substances (by GC) – Impurity B – Impurity C – Impurity G – Unspecified Impurities – Total Impurity | % % % % % | NMT 0.15 NMT 0.15 NMT 0.10 NMT 0.10 NMT 0.50 |
| Residual Solvent – IPA – Toluene – DMF – *Benzene | ppm ppm ppm ppm | NMT 5000 NMT 890 NMT 880 NMT 2 |
| Assay (on anhydrous basis) | % | 98.0 – 102.0 |
| Cis isomer | % | 23.0 – 27.0 |
| Trans isomer | % | 73.0 – 77.0 |
*Benzene is not used in process, but tested due to the use of Toluene
PACKAGING OPTIONS
25 Kg HDPE Drums
STORAGE
Store in a sheltered place away from sources of heat and moisture
CERTIFICATION
WHO-GMP, DMF & CEP
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
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