INTRODUCTION
Oxalyl chloride is a colorless liquid with pungent odor. The chloride is volatile and moisture sensitive. As a useful reagent employed in a variety of chemical syntheses, it finds applications in APIs, intermediates, and agrochemicals.
Manufacture
The acid chloride is produced by chlorination of oxalic acid by using phosphorous pentachloride.
| Synonyms | Ethanedioyl dichloride Oxalic acid dichloride |
| CAS no. | 79-37-8 |
| EINECS no. | 201-200-2 |
| Molecular formula | C2Cl2O2 |
| Molecular weight | 126.93 |
| Structure |  |
Pharmaceutical Applications
Oxalyl chloride is a KRM to produce the following APIs:
| Tivantinib | anti-cancer drug |
| Diclofenac | anti-inflammatory drug |
Agrochemicals Applications
The acid chloride is also a raw material in manufacture of many plant protection products such as:
| Chinomethionat |
| Triflumuron |
| Metsulfuron |
| Bensulfuron-Methyl |
| Pyrimidine-sulfuron |
Other Vital Applications
| as catalyst in production of ketones and aldehydes from alcohols |
| as chlorinating agent to make acid chlorides from acids |
| as a reagent to convert aromatic products into corresponding acids |
| in manufacture of dioxane tetra-ketone and 2,3-dichloroquinoxaline-6-carbonyl chloride |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Clear colorless to pale yellow liquid |
| Purity by GC | % | Min 99.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
250 kg UN approved steel drum
ExSyn offers oxalyl chloride on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
Linoleic acid is a polyunsaturated omega-6 fatty acid. It is a colorless liquid that is virtually insoluble in water but soluble in many organic solvents. It typically occurs in nature as a triglyceride (ester of glycerin) rather than as a free fatty acid.
Ethyl Linoleate belongs to the chemical class of fatty acids, which are organic compounds with one or more long hydrocarbon chains. These molecules are characterized by having two carbons atoms with a double bond between them.
2-Picolinic acid, an organic compound, is a derivative of pyridine with a carboxylic acid substituent at the 2-position. It is a white solid that is soluble in water.
2-Phenylethylamine is a water-soluble amine with a fishy odor. It is often referred to simply as “phenethylamine”, but that can also be interpreted as 1-phenylethylamine.
4-Amino-1,2,4-triazole is an organic solid belonging to the heterocyclic category of compounds. By virtue of presence of 3 nitrogen atoms, the molecule is biologically active and thus acts as antimicrobial and antifungal agent.
4’-Cyanoacetophenone is an organic solid. It belongs to cyclic nitriles category. The presence of cyano group makes the compound reactive to form various intermediates and a few APIs. In organics syntheses, it also used as a catalyst.
3- Bromothianisole is a brominated aromatic compound with an active methyl thio group for oxidation. It has many applications in pharmaceutical and biotech industries as an intermediate for the synthesis of various organic compounds
Dichloroacetyl chloride, acronymed DCAC, is an organic solvent that belongs to the category of acid chlorides. Its uses include manufacture of APIs, agrochemicals, and a series of intermediates. It is also applied in synthesis of biologically active compounds.
1-(Difluoromethyl)-4-nitro-1H-pyrazole is a difluoromethyl aromatic compound with an active nitro group for reduction. It is used as an organic synthesis key starting material and intermediate in APIs.