INTRODUCTION

Oxalyl chloride is a colorless liquid with pungent odor. The chloride is volatile and moisture sensitive. As a useful reagent employed in a variety of chemical syntheses, it finds applications in APIs, intermediates, and agrochemicals.

Manufacture

The acid chloride is produced by chlorination of oxalic acid by using phosphorous pentachloride.

SynonymsEthanedioyl dichloride
Oxalic acid dichloride
CAS no.79-37-8
EINECS no.201-200-2
Molecular formulaC2Cl2O2
Molecular weight126.93
Structure

Pharmaceutical Applications

Oxalyl chloride is a KRM to produce the following APIs:

Tivantinibanti-cancer drug
Diclofenacanti-inflammatory drug

Agrochemicals Applications

The acid chloride is also a raw material in manufacture of many plant protection products such as:

Chinomethionat
Triflumuron
Metsulfuron
Bensulfuron-Methyl
Pyrimidine-sulfuron

Other Vital Applications

as catalyst in production of ketones and aldehydes from alcohols
as chlorinating agent to make acid chlorides from acids
as a reagent to convert aromatic products into corresponding acids
in manufacture of dioxane tetra-ketone and 2,3-dichloroquinoxaline-6-carbonyl chloride

SPECIFICATIONS

TestUnitSpecification
AppearanceClear colorless to pale yellow liquid
Purity by GC%Min 99.0

STORAGE
The product is stored at ambient temperature.

PACKING
250 kg UN approved steel drum

ExSyn offers oxalyl chloride on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.

More Products
In focus: Teprenone (Geranylgeranylacetone; GGA)
Products in focus · 31/03/2026

Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.

READ MORE
In focus: Ciclopirox Olamine Ph.Eur.
Products in focus · 24/03/2026

Ciclopirox Olamine (CPO)  is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.

READ MORE
In focus: N,N-Dimethylglycine sodium salt (DMG Na)
Products in focus · 17/03/2026

N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.

READ MORE
In focus: Blown Castor Oil (15-17 Poise)
Products in focus · 10/03/2026

Blown Castor Oil (15-17 Poise) is a modified grade of Castor oil. The “15-17 Poise” specification refers to its viscosity range, indicating a medium-viscosity blown oil suitable for industrial applications requiring improved body, tackiness, and elasticity compared to regular castor oil.

READ MORE
In focus: Dimethyl Amino Ethanol (DMAE)
Products in focus · 03/03/2026

Dimethylaminoethanol (DMAE) is a is a tertiary amine that is ethanolamine having two N-methyl substituents. It is clear & colourless to pale yellow liquid with ammoniacal odor.  DMAE is stable at room temperature and is completely miscible with water as well as organic solvents such as alcohols and ethers. It decomposes at high temperatures. It is a versatile chemical intermediate primarily used as a curing agent for polyurethane foams and epoxy resins.

READ MORE
In focus: 1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN)
Products in focus · 24/02/2026

1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.

READ MORE
In focus: Adenosine
Products in focus · 17/02/2026

Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.

READ MORE
In focus: Methyl-2- Methoxy-5-Sulfamoyl Benzoate
Products in focus · 10/02/2026

Methyl-2-Methoxy-5-Sulfamoyl Benzoate (MSMB) is a sulfur containing organic building block acting as a chemical intermediate. MSMB contains ester and sulfamoyl functional groups, which make it useful as a pharmaceutical and fine-chemical intermediate.

READ MORE
In focus: Imidazolidinyl Urea
Products in focus · 03/02/2026

Imidazolidinyl urea is a widely used antimicrobial preservative in the cosmetic and personal care industry. It is a formaldehyde-releasing compound that effectively inhibits the growth of bacteria, yeast, and molds, thereby extending the shelf life of formulations. Due to its broad-spectrum efficacy and cost-effectiveness, it is commonly used in rinse-off and leave-on products within regulated concentration limits.

READ MORE